Chemical Formula | C8H8N2 |
Molecular Weight | 132.16 g/mol |
Appearance | Solid |
Odor | Odorless (usually) |
Melting Point | Approx. 176 - 178 °C |
Solubility In Water | Poorly soluble |
Solubility In Organic Solvents | Soluble in some organic solvents like ethanol |
Pka Value | Around 6.8 |
Stability | Stable under normal conditions |
Reactivity | Can react with electrophiles due to the presence of nitrogen atoms |
What are the main application fields of Benzylimidazole
Benzyl imidazole is one of the organic compounds, which has a wide range of applications and is involved in various fields.
The first and the field of medicine. Benzyl imidazole compounds often have unique pharmacological activities, or can be used as key raw materials for drug development. Taking antibacterial drugs as an example, they may interfere with the physiological metabolism of bacteria, achieve antibacterial effect, and provide help for the treatment of bacterial infections. In the exploration of anti-tumor drugs, some benzyl imidazole derivatives have been found to affect the proliferation and apoptosis of tumor cells, and are expected to become new anti-tumor drugs.
Furthermore, in the field of materials science. This compound can be used to prepare special functional materials. For example, when preparing optical materials, it can impart specific optical properties to the material, such as changing the material's light absorption and emission characteristics, so that the material can show unique application value in optoelectronic devices, such as Light Emitting Diode, laser materials, etc. In the modification of polymer materials, the addition of benzyl imidazole can improve the thermal stability and mechanical properties of polymer materials, and broaden the application range of materials.
The field of catalysis is also indispensable. Benzyl imidazole can be used as a ligand to complex with metal ions to form a metal-ligand complex, which often has high catalytic activity. In organic synthesis reactions, it can catalyze reactions such as carbon-carbon bond formation and functional group conversion, improve reaction efficiency and selectivity, and help the development of organic synthesis chemistry to achieve a greener and more efficient synthesis route.
In addition, in agricultural chemistry, benzyl imidazoles may have plant growth regulation functions, or can regulate plant growth and development processes, such as affecting plant rooting, flowering, and fruiting stages, providing new ways for agricultural production and quality improvement; or as pesticide active ingredients, resist pests and diseases, and ensure the healthy growth of crops.
What are the synthesis methods of Benzylimidazole?
Benzyl imidazole is also an organic compound. Although the method of its synthesis has not been detailed in ancient books, there are many scholars today.
One method can be obtained by the reaction of imidazole and benzyl halide through nucleophilic substitution. Imidazole is nucleophilic, and the halogen atom of benzyl halide is quite active. When the two meet, the nitrogen atom of imidazole attacks the carbon atom of benzyl halide, and the halogen atom leaves, then forms benzyl imidazole. During the reaction, a base is often needed as an acid binding agent to promote the reaction, and in appropriate solvents, such as acetonitrile, dimethylformamide, etc., to increase the solubility of the reactants and make the reaction smooth. < Br >
There are also benzyl imidazole synthesized from benzaldehyde, glyoxal and ammonia through multi-step reaction. Benzyl imidazole is synthesized by benzaldehyde and glyoxal condensation under specific conditions, and then interacts with ammonia. After various changes such as cyclization, benzyl imidazole is finally obtained. This approach is slightly complicated, but the raw material is easy to obtain, and it is also one of the synthesis processes.
Furthermore, the method of transition metal catalysis can be used. Using metals such as palladium and copper as catalysts, the substrate containing imidazole structure is coupled with benzyl reagents to obtain benzyl imidazole. This method has good selectivity and milder reaction conditions, which is a good strategy for the synthesis of benzyl imidazole.
All these synthetic methods have their own advantages and disadvantages, and scholars need to choose the best one according to actual needs, such as the cost of raw materials, the difficulty of reaction, and the purity of the product, so as to form the synthesis of benzyl imidazole.
What are the physical and chemical properties of Benzylimidazole?
Benzyl imidazole, organic compounds and the like. Its physical and chemical properties are quite specific, and are hereby described in detail.
Looking at its physical properties, under room temperature, it is mostly in a solid state, but due to the difference of substituents, or some are liquid. Its color is often close to colorless to slightly yellow, and its appearance is clean. The number of melting points varies according to its specific structure, probably within a certain temperature range, which is one of the characteristics to distinguish its purity. And its solubility also has characteristics. In organic solvents such as ethanol and acetone, it often has good solubility and can be miscible with it. However, the solubility in water depends on the number of polar groups in the molecular structure. If the polarity is moderate, it can also have a certain degree of solubility.
In terms of its chemical properties, benzyl imidazole is active and reactive. Its imidazole ring contains an electron-rich structure, so it can participate in a variety of chemical reactions. For example, it can react with electrophilic reagents to introduce new substituents on the ring, which can expand the diversity of its chemical structure. And because nitrogen atoms have lone pairs of electrons, they can be used as ligands to complex with metal ions to form stable complexes, which are important in catalytic chemistry, materials science and other fields. And under appropriate conditions, acid-base reactions can occur, showing a certain alkalinity, and can form salts with acids. This property is also the basis for its chemical applications.
All these physical and chemical properties make benzyl imidazole indispensable in many industries such as medicine, materials, and chemical industry, providing an important chemical basis for the research and development of new materials and the creation of specific drugs.
What is the price range of Benzylimidazole in the market?
Benzyl imidazole is in the market, but its price is difficult to determine. The price often varies due to factors such as quality, quantity, supply and demand in the market, and the origin of the product.
If the quality is excellent, the price may be slightly higher; if the quality is average, the price should be slightly lower. If the quantity is huge, it may be beneficial; if the quantity is small, the price may not be reduced. The demand of the market is prosperous, and the price may rise; if the market is weak, the price may also fall.
Furthermore, the origin of the product is different, and the cost is also different, and the price is different. However, roughly speaking, the price per gram may be between a few yuan and tens of yuan. This is only a guess and cannot be fully trusted. To know the exact price, you need to consult the intercity merchants, vendors of chemical materials, or look up the price list of chemical products to obtain a more accurate number.
What are the manufacturers of Benzylimidazole?
Benzylimidazole (Benzylimidazole), an organic compound, is also widely used in the chemical industry, medicine and other fields. However, as far as I know, there is no detailed list of manufacturers specializing in its production in ancient books.
At present, within the four seas, science and technology are improving, and the manufacturers of this product may be scattered in various places. It is mostly in the prosperous fields of the chemical industry, such as Jiangsu, Zhejiang, Guangdong and other places in China, or there are manufacturers specializing in chemical synthesis involved in the production of this product.
In Western countries, there are also many chemical giants, whose R & D and capacity are strong, or there are also those who produce benzylimidazole. However, if you want to know which manufacturers are there, you need to visit the chemical directory, industry exhibition materials, or consult the experts of the chemical industry to get detailed information. And the rise and fall of manufacturers is impermanent, the new ones are born every day, and the old ones may change course. Therefore, if you want accurate information, it is advisable to pay attention to the dynamics of the industry.