What is the chemical structure of 7H- (1) Benzopyrano (3 ', 2': 3,4) pyrido (1,2-a) benzimidazole-6-carbonitrile, 3- (diethylamino) -7-imino-?

This is a rather complex organic compound named 3- (diethylamino) -7-imino-7H- (1) benzopyrano (3 ', 2': 3,4) pyridino (1,2-a) benzimidazole-6-formonitrile. To clarify its chemical structure, it can be analyzed one by one from each part.

The first sentence "7H- (1) benzopyrano (3 ', 2': 3,4) pyridino (1,2-a) benzimidazole", this is a thick ring system. The "benzopyran" part is formed by fusing the benzene ring with the pyran ring. The pyran ring is a six-membered heterocyclic ring containing oxygen, and the benzene ring is fused with it, giving it a specific chemical activity and spatial structure. "Pyridino (1,2-a) benzimidazole" is also a fused ring, pyridine is a six-membered heterocyclic ring containing nitrogen, and benzimidazole is fused with the benzene ring and the imidazole ring. The imidazole ring is a five-membered heterocyclic ring containing two nitrogen atoms. The rings fuse with each other to construct a complex and unique basic skeleton.

Looking at the substituent again, "3- (diethylamino) ", that is, at the 3rd position of the fused ring system, there is a diethylamino group. Diethylamino is an organic amine group, which is connected by two ethyl groups and nitrogen atoms, and has certain electron-giving properties, which can affect the electron cloud distribution and chemical properties of the compound. "7-imino", there is an imino group (= NH) at the 7th position, and the presence of the imino group changes the electronic environment of this position. "6-formonitrile" indicates that there is a methonitrile group (-CN) connected at the 6th position, and the methonitrile group has high chemical activity and can participate in many chemical reactions.

In summary, the chemical structure of this compound is composed of a complex fused ring skeleton and substituents at specific locations, and the interaction of each part gives it unique physical and chemical properties, which may be of great significance in the fields of organic synthesis and medicinal chemistry.

What are the physical properties of 7H- (1) Benzopyrano (3 ', 2': 3,4) pyrido (1,2-a) benzimidazole-6-carbonitrile, 3- (diethylamino) -7-imino-?

3- (diethylamino) -7-imino-7H- (1) benzopyrano (3 ', 2': 3,4) pyridino (1,2-a) benzimidazole-6-formonitrile This substance has many physical properties. Its appearance or a specific form, mostly crystalline solids, such forms are common in many organic compounds, and the crystalline structure gives it a relatively stable physical state.

Melting point is one of the key physical properties, but its specific value varies depending on the precise measurement conditions. Roughly speaking, at a certain temperature range, at this temperature, the substance melts from a solid state to a liquid state, and this temperature range reflects the strength of intermolecular forces.

In terms of solubility, it shows different performances in organic solvents. In polar organic solvents such as ethanol and dimethyl sulfoxide, there may be a certain solubility, because such solvents can form specific intermolecular interactions with the compound, such as hydrogen bonds, van der Waals forces, etc., which promote the molecule to disperse in the solvent system. In water, the solubility may be extremely low, because the non-polar part of the molecular structure accounts for a large proportion, and it is difficult to form effective interactions with water molecules.

In addition, the compound may have specific optical properties. Under the irradiation of specific wavelengths of light, it exhibits unique absorption and emission characteristics, or due to the existence of a conjugate system inside the molecule, electrons transition between different energy levels, resulting in characteristic spectra. This optical property may have potential application value in optoelectronic devices, fluorescence analysis and other fields.

7H- (1) Benzopyrano (3 ', 2': 3,4) pyrido (1,2-a) benzimidazole-6-carbonitrile, 3- (diethylamino) -7-imino- What are the chemical properties?

This is a rather complex organic compound named 3- (diethylamino) -7-imino-7H- (1) benzopyrano (3 ', 2': 3,4) pyridino (1,2-a) benzimidazole-6-formonitrile. Its chemical properties are unique and contain a polycyclic structure, which may be of great significance in the fields of organic synthesis and medicinal chemistry.

In terms of physical properties, this compound may be in a solid state. Due to the presence of many cyclic structures, the intermolecular force is strong. In view of the existence of heteroatoms such as nitrogen and oxygen in the structure, its solubility may be characteristic. Nitrogen atoms can participate in the formation of hydrogen bonds. If they form hydrogen bonds with solvent molecules in polar solvents, they may exhibit some solubility; however, due to the complex and large structure, there are also many non-polar parts, and the solubility in non-polar solvents may be poor.

Regarding chemical properties, nitrile groups (-CN) in molecules have high reactivity and can participate in a variety of reactions, such as hydrolysis to form carboxylic acids, or addition reactions with nucleophiles. Nitrogen atoms of imino groups (-NH-) have lone pairs of electrons, which can participate in the reaction as nucleophiles, or protonate under acidic conditions, affecting the overall charge distribution and reactivity of molecules. The diethylamino group can enhance the electron cloud density of benzopyran, pyridine and benzimidazole rings, making these rings more prone to electrophilic substitution reactions. And the polycyclic conjugate system of the compound may endow it with certain optical properties, such as under the irradiation of specific wavelengths, it may produce fluorescence phenomenon, which may have potential applications in the field of optical materials.

Its complex chemical structure and diverse chemical properties bring many possibilities for chemical research and related application fields, and can be used as a key intermediate for the synthesis of new functional materials or drugs.

What is the main use of 7H- (1) Benzopyrano (3 ', 2': 3,4) pyrido (1,2-a) benzimidazole-6-carbonitrile, 3- (diethylamino) -7-imino-?

3- (diethylamino) -7-imino-7H- (1) benzopyrano (3 ', 2': 3,4) pyridino (1,2-a) benzimidazole-6-formonitrile This substance may have many wonderful uses in medical practice.

Looking at the structure of this compound, it has a unique chemical structure. From the perspective of pharmacological exploration, it may be able to contact specific targets in organisms. Its imino and diethylamino groups give it unique chemical activity, or can be embedded in specific protein check points, interfering with protein-protein interactions, and affecting the pathway of cell signaling. In this way, it may emerge in the key process of regulating cell proliferation and differentiation, and may have potential value in the treatment of tumors, immune disorders and other diseases.

In the process of drug development, it can be used as a lead compound. After structural modification and optimization, its activity and pharmacokinetic properties can be adjusted. Such as modifying the side chain, changing its lipophilicity, water solubility, increasing its bioavailability, and reducing toxic side effects. And such complex polycyclic structures may be the key to solving problems in the creation of drugs for neurological diseases. Or it can act on neurotransmitter receptors, regulate nerve conduction, and find new therapeutic paths for diseases such as epilepsy and Parkinson's disease.

In addition, in the field of materials science, or due to its unique electronic structure and chemical stability, it can be used as functional materials. For example, it is used in optoelectronic devices, giving the devices special optical and electrical properties, adding a new way for material innovation.

However, its specific use still needs to be rigorously experimented and studied in depth before it can be definitively clarified in order to achieve the macro effect of saving the world.

7H- (1) Benzopyrano (3 ', 2': 3,4) pyrido (1,2-a) benzimidazole-6-carbonitrile, 3- (diethylamino) -7-imino- What are the synthesis methods?

To prepare 3- (diethylamino) -7-imino-7H- (1) benzopyrano (3 ', 2': 3,4) pyridino (1,2-a) benzimidazole-6-formonitrile, there are many methods, which are selected as the following.

First, benzimidazole, pyridine and benzopyran derivatives with corresponding substituents are used as starting materials. First, benzimidazole derivatives and specific pyridine derivatives are condensed in organic solvents under suitable reaction conditions, using base as catalyst, to form preliminary intermediates. This process requires precise control of the reaction temperature and time. The temperature should be maintained in a moderate range, such as between 40 and 60 degrees Celsius, and the reaction time is about 6 to 8 hours, so that the reaction is sufficient and the side reactions are minimized.

Then, the resulting intermediate is reacted with a reagent containing diethylamino in another reaction stage. This step may require the use of a specific condensing agent, and the reaction environment needs to be anhydrous and oxygen-free, and the reaction temperature needs to be adjusted to a suitable range, such as 80 to 100 degrees Celsius. After about 5 to 7 hours, the diethylamino group is successfully introduced, and then the target product is generated.

Second, different paths can be started. First, the skeleton of the fusion of benzopyran and pyridine is constructed, and the compound containing the corresponding functional group is cycled under acidic or basic catalysis through a specific cyclization reaction. This cyclization reaction conditions are severe, and precise control of pH, temperature and reaction time is required. For example, in acidic catalysis, a specific concentration of acid is used as the catalyst, the temperature is controlled at 50 to 70 degrees Celsius, and the reaction is about 4 to 6 hours.

After cyclization, the construction of the benzimidazole part and the introduction of the amino substituent are carried out. This process requires multiple steps of reaction, each step requires fine operation, including the separation and purification of the reaction intermediate, to ensure the purity and yield of the final product. < Br >
Although the method of preparing this compound is complex, the synthesis efficiency and product quality can be effectively improved by fine regulation of reaction conditions and careful selection of reagents and catalysts.