What is the chemical structure of 7- [[ (4S) -5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl] oxy] -N, N, 2-trimethyl-1H-benzimidazole-5-formamide

The chemical structure of this organism can be analyzed step by step according to its name.

"7 - [%[( 4 S) -5, 7-diene-3,4-dioxide-2H-1-benzopyran-4-yl] oxy] -N, N, 2-trimethyl-1H-indole-5-acetamide".

According to the main structure, "1H-indole" is a nitrogen-containing bilicyclic aromatic structure, in which a benzene ring is fused with a five-membered nitrogen-containing pyrrole ring. At the 2nd position of "1H-indole", there is "N, N-dimethyl" substitution, and at the 5th position, there is an "acetamide" group, that is, "-CONHCH -2 CH".

Look at another part connected to indole, " (4S) -5,7-diene-3,4-dioxide-2H-1-benzopyran-4-yl", which is a monobenzopyran structure. Its benzene ring is fused with the pyran ring. The 5th and 7th positions are double bonds, and the aerobic atoms at the 3rd and 4th positions form oxides, and the 4th position is the S configuration. The structure is connected to the 7th position of indole by "4-yloxy", that is, "-O-".

In this way, the structure of this organic substance is clearly presented, and each substitution is connected according to the corresponding position, forming a unique chemical structure.

What are the physical properties of 7- [[ (4S) -5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl] oxy] -N, N, 2-trimethyl-1H-benzimidazole-5-formamide

From the perspective of "Tiangong Kaiwu", the (4S) -5,7-diene-3,4-dioxide-2H-1-benzopyran-4-yloxy, N, N, 2-trimethyl-1H-benzimidazole-5-acetamide mentioned here is a rather complex organic compound.

In terms of physical properties, generally speaking, such organic compounds are mostly in solid form, but they will also vary due to changes in ambient temperature and pressure. Its melting point and boiling point are affected by intermolecular forces, such as hydrogen bonds, Van der Waals forces, etc. In general, due to the existence of many polar groups in the molecule, such as carbonyl, ether bonds, etc., the intermolecular force is strong, so the melting point and boiling point are relatively high.

In terms of solubility, given that its molecular structure contains polar parts, it may have a certain solubility in polar solvents, such as water and ethanol. However, due to the presence of large non-polar structures such as benzene rings, it also has a certain solubility in non-polar solvents, such as n-hexane. The color state of this compound, or a white to light yellow solid, is related to the conjugated system in the molecular structure. The degree of conjugation affects its absorption and reflection of light, and then presents a specific color. The density is also closely related to the molecular structure, and the degree of compactness of the molecular structure, the type and number of atoms will all have an effect on the density.

Overall, the physical properties of (4S) -5,7-diene-3,4-dioxide-2H-1-benzopyran-4-yloxy, N, N, 2-trimethyl-1H-benzimidazole-5-acetamide are determined by the interaction of various groups in the molecular structure, and exhibit different characteristics under different conditions.

What is the main use of 7- [[ (4S) -5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl] oxy] -N, N, 2-trimethyl-1H-benzimidazole-5-formamide

The compound you mentioned has a long name and a complex structure. In the field of medicine, this substance may be used as a key raw material for innovative drug research and development. Due to its unique chemical structure, it may be able to target specific disease targets and exert the effect of precision therapy, which is expected to overcome difficult diseases and bring good news to patients.

In the field of materials science, this compound may endow materials with novel characteristics. For example, by enhancing the stability of materials and improving their physical properties, it can be applied to high-end scientific and technological products to promote the progress of electronics, aerospace and other industries.

In the field of fine chemicals, it can be used as an intermediate for the synthesis of special chemicals. With its structural characteristics, high value-added fine chemicals can be synthesized to meet the diverse industrial needs and promote the upgrading of the chemical industry.

In short, this 7 - [ [( 4 S) -5,7 -diene-3,4 -dioxide-2H-1 -benzopyran-4 -yl] oxy] -N, N, 2 -trimethyl-1H -benzimidazole-5 -acetamide has important potential uses in many fields and is of great significance for promoting the development of various industries.

What are the synthesis methods of 7- [[ (4S) -5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl] oxy] -N, N, 2-trimethyl-1H-benzimidazole-5-formamide

To prepare 7- [ (4S) -5,7-diene-3,4-dioxide-2H-1-benzopyran-4-yl] oxy] -N, N, 2-trimethyl-1H-benzimidazole-5-acetamide, the following methods can be referred to:

The starting material is selected with suitable substituted benzopyran and benzimidazole derivatives. First, with (4S) -5,7-diene-3,4-dioxide-2H-1-benzopyran-4-yl structure, through a specific nucleophilic substitution reaction, the hydroxyl group is interacted with a suitable halogen or sulfonate to form an ether bond, and the product containing 7- [ (4S) -5,7-diene-3,4-dioxide-2H-1-benzopyran-4-yl] oxygen is obtained.

At the same time, p-benzimidazole derivatives introduce methyl at the N atom, and methylation reagents such as iodomethane can be used to achieve N, N, 2-trimethylation under alkali catalysis.

After that, the product in the ether-containing bond is connected to the N, N, 2-trimethyl-1H-benzimidazole-5-acetamide structural fragment. It can be reacted in suitable solvents such as dichloromethane, N, N - dimethylformamide (DMF) in the presence of condensing agents such as dicyclohexyl carbodiimide (DCC), 1 - (3 - dimethylaminopropyl) -3 - ethylcarbodiimide hydrochloride (EDC · HCl), etc., through dehydration and condensation to obtain the target product 7- [ (4S) -5,7 - diene - 3,4 - dioxide - 2H - 1 - benzopyran - 4 - yl] oxy] - N , N, 2-trimethyl-1H-benzimidazole-5-acetamide.

Each step of the reaction needs to pay attention to the precise control of the reaction conditions, such as temperature, reaction time, reagent dosage, etc., to ensure that the reaction is efficient, selective, and reduce side reactions. After the reaction is completed, the product is often purified by means of column chromatography, recrystallization, etc., to obtain high-purity target compounds.

7- [[ (4S) -5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl] oxy] -N, N, 2-trimethyl-1H-benzimidazole-5-formamide What are the precautions during use

7 - [[ (4S) -5,7 - diene - 3,4 - dioxide - 2H - 1 - benzopyran - 4 - yl] oxy] - N, N, 2 - trimethyl - 1H - benzimidazole - 5 - acetamide This compound should pay attention to the following matters during use:

First, because of its specific chemical structure and activity, laboratory safety procedures must be strictly followed during operation. Be sure to wear appropriate protective equipment, such as lab clothes, gloves and goggles, to avoid direct contact of the compound with the skin and eyes. In case of inadvertent contact, rinse with a large amount of water immediately and seek medical treatment in time according to the specific situation.

Second, the reactivity of this compound requires precise control of the reaction conditions. Factors such as temperature, pH (pH) and reaction time may all affect the reaction process and product purity. Before conducting related reactions, the reaction conditions must be fully optimized and explored, and the best reaction parameters must be determined through experimental data.

Third, in view of its complex chemical structure, when analyzing and identifying it, a variety of analytical methods, such as nuclear magnetic resonance (NMR), mass spectrometry (MS) and infrared spectroscopy (IR), need to be used to accurately determine its structure and purity. When analyzing these analytical data, professional knowledge and experience are required to ensure the accuracy of the results.

Fourth, the storage of this compound should not be ignored. It should be stored in a suitable environment according to its chemical properties. Generally speaking, it should be placed in a dry, cool and well-ventilated place, away from fire sources and oxidants, etc., to prevent deterioration or dangerous reactions.

Fifth, detailed experimental records should be made during use, covering the source, dosage, reaction conditions and experimental results of the compound. These records not only help to repeat and optimize subsequent experiments, but also can be traced and analyzed when problems occur.