6 Chloro 5 2 3 Dichlorophenoxy 2 Methylsulfanyl 1h Benzoimidazole
quinoline thiophene imidazole thiazole

6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzoimidazole

    Specifications

    HS Code

    825414

    Chemical Formula C14H9Cl3N2OS
    Molecular Weight 361.66 g/mol
    Appearance Solid (predicted based on similar benzoimidazole compounds)
    Solubility In Water Low (due to non - polar groups like the aromatic rings and methylsulfanyl group)
    Solubility In Organic Solvents Soluble in non - polar or moderately polar organic solvents such as chloroform, dichloromethane (predicted from structure)
    Stability Stable under normal conditions but may react with strong oxidizing or reducing agents

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    General Information
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    What are the chemical properties of 6-chloro-5- (2,3-dichlorophenoxy) -2-methylsulfanyl-1H-benzoimidazole
    6-Chloro-5- (2,3-dichlorophenoxy) - 2-methylthio-1H-benzimidazole, which is an organic compound. Looking at its structure, it consists of a benzimidazole core framework, which is connected with chlorine atoms, dichlorophenoxy and methylthio groups. Its chemical properties are rich, and the groups contained in the cause have their own characteristics.
    Let's talk about the chlorine atom first, the halogen atom has electron absorption, which can affect the molecular electron cloud distribution, reduce the electron cloud density of the benzimidazole ring, and then affect its electrophilic substitution reaction activity. Usually, the electron cloud density of the adjacent para-position of the halogen atom is relatively high, and the electrophilic reagent is easy to attack this position. However, due to its electron absorption, the reactivity will be reduced compared with the benzene ring itself.
    Dichlorophenoxy part, the phenoxy group is the power supply group, which can increase the electron cloud density of the benzimidazole ring and improve the electrophilic substitution activity. However, the two chlorine atoms have an electron-absorbing induction effect, which combined to affect the overall reactivity of the molecule. The steric resistance of this group cannot be ignored, which will hinder the reagent from approaching the specific position of the molecule in the reaction and affect the reaction selectivity. In the methylthio group, the sulfur atom has moderate electronegativity and a certain power supply capacity, which can increase the electron cloud density of the benzimidazole ring, which is conducive to electrophilic substitution. And the outer layer of the sulfur atom is rich in electrons, which can participate in the reaction as an electron donor, such as forming coordination bonds with metal ions.
    In terms of acidity and alkalinity, the nitrogen atom on the 1H-benzimidazole ring has lone pair electrons, which are alkaline and can combine with acids to form salts. However, the electronic effect of other substituents will change the electron cloud density of the nitrogen atom, thereby affecting its alkalinity.
    In terms of thermal stability, the atoms in the molecule of the compound are connected by covalent bonds to form a stable structure. However, at high temperatures, some chemical bonds with relatively weak bond energy, such as carbon-sulfur bonds, carbon-halogen bonds, etc., may break and cause molecular decomposition.
    In terms of solubility, because it is an organic compound, it contains more hydrophobic groups and has limited solubility in water. However, it can be soluble in some organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide, etc. The specific solubility varies depending on the interaction between the solvent and the compound.
    This compound has unique chemical properties and may have potential application value in the fields of organic synthesis, medicinal chemistry, etc. It can be used as an intermediate to participate in various reactions and build more complex compound structures.
    What is the preparation method of 6-chloro-5- (2,3-dichlorophenoxy) -2-methylsulfanyl-1H-benzoimidazole
    The preparation method of 6-chloro-5- (2,3-dichlorophenoxy) - 2-methylthio-1H-benzimidazole is an important technology in the field of chemical synthesis. The preparation of this compound follows the following method.
    The starting material is selected from suitable halogenated benzene, benzimidazole derivatives and sulfur-containing reagents. First, the halogenated benzene and benzimidazole derivatives are subjected to nucleophilic substitution in an organic solvent under specific reaction conditions with a suitable base as a catalyst. This step requires controlling the reaction temperature and time. Generally, the temperature is between 50 ° C and 120 ° C, and the reaction time is about 3 to 8 hours, so that the halogen atom of the halogenated benzene is replaced with the specific position of the benzimidazole derivative to form a preliminary intermediate.
    Then, the preliminary intermediate is reacted with the sulfur-containing reagent in another reaction stage. This reaction may require the assistance of another catalyst, the solvent should also be selected, and the reaction temperature needs to be finely regulated, between about 30 ° C and 80 ° C, for 2 to 6 hours, so that the sulfur-containing group is successfully connected, and the final result is 6-chloro-5- (2,3-dichlorophenoxy) -2-methylthio-1H-benzimidazole.
    The whole preparation process requires strict control of the reaction conditions, such as temperature, time, ratio of reactants, catalyst type and dosage. If there is a slight difference, the yield may not be high and the product may be impure. And after each step of the reaction, suitable separation and purification methods, such as column chromatography, recrystallization, etc., should be used to obtain pure products, which will lay the foundation for subsequent research and application.
    In which fields is 6-chloro-5- (2,3-dichlorophenoxy) -2-methylsulfanyl-1H-benzoimidazole used?
    6-Chloro-5- (2,3-dichlorophenoxy) - 2-methylthio-1H-benzimidazole is useful in many fields.
    In the field of medicine, it may have unique effects. Because benzimidazole compounds often have various biological activities, or can be used as lead compounds in drug development. By modifying and optimizing their structures, it is expected to produce new antibacterial, antiviral and anti-tumor drugs. If the precise molecular design, the compound may be able to target specific pathogenic factors and block the reproduction of bacteria or tumor cells, which is a new way to solve the medical problem. < Br >
    In the field of agriculture, it may become a key ingredient in the creation of pesticides. Benzimidazoles are commonly found in pesticides and have the ability to sterilize and insecticide. The chlorine, phenoxy and methylthionyl structures of this compound may give them high-efficiency control over specific crop diseases and pests, helping to improve crop yield and quality and protect the stability of agricultural production.
    In the field of materials science, there are also potential applications. Its special chemical structure may enable it to interact with specific materials, and after rational design, it may be used as a material modifier. If added to polymer materials, it may improve its properties, such as enhancing stability and improving weather resistance, thereby broadening the application scope of materials and shining in aviation, automotive, construction and other industries.
    Furthermore, it can be used as an important chemical tool in the process of scientific research and exploration. By studying its reaction characteristics and interactions with other substances, scientists can deepen their understanding of the mechanism of organic chemistry, providing assistance for the development of new chemical reaction paths and the innovation of chemical synthesis methods, and promoting the vigorous development of chemistry.
    What is the market outlook for 6-chloro-5- (2,3-dichlorophenoxy) -2-methylsulfanyl-1H-benzoimidazole?
    6-Chloro-5- (2,3-dichlorophenoxy) - 2-methylthio-1H-benzimidazole, which is an organic compound. Its market prospect can be compared to "Tiangong Kaiwu", and the characteristics of the substance and the needs of the world can be known in detail.
    Looking at its properties, its structure is unique, chlorine, phenoxy and methylthio coexist, or it has special chemical activities and physical properties. In the field of medicine, its structure is similar to that of bioactive molecules, or it can be used to create new drugs, such as antibacterial and anti-tumor genera. Nowadays, there is a strong demand for new antibacterial and anti-tumor drugs in the pharmaceutical market. If this compound is proved to be effective and safe by research, it will be favored and have broad prospects.
    In the agricultural field, it may be used as a pesticide ingredient. Its structure contains polyhalogen atoms, which may have insecticidal and bactericidal properties. The current demand for green and efficient pesticides is increasing. If this compound can meet the standards of environmental protection and high efficiency, it can also occupy a place in the agricultural market.
    However, its market expansion also poses challenges. Synthesis of this compound may require complex processes and high costs. If the synthesis path cannot be optimized and costs reduced, it may be difficult to be price competitive. And before being put into the market, it needs to undergo strict safety and Environmental Impact Assessment to meet legal requirements.
    In summary, the market prospect of 6-chloro-5- (2,3-dichlorophenoxy) -2-methylthio-1H-benzimidazole is both opportunities and challenges. With scientific research and rational development, it is expected to emerge in the fields of medicine, agriculture and other fields and gain a considerable market share.
    What are the safety and toxicity of 6-chloro-5- (2,3-dichlorophenoxy) -2-methylsulfanyl-1H-benzoimidazole
    6-Chloro-5- (2,3-dichlorophenoxy) - 2-methylthio-1H-benzimidazole, the safety and toxicity of this substance are related to many aspects, let me tell you one by one.
    First, in terms of safety, considering its chemical structure, benzimidazole structures are widely found in many compounds. However, this compound contains specific groups such as chlorine atoms and methylthio groups. The presence of chlorine atoms may affect its chemical activity and stability. If it is in a specific environment, chlorine atoms may undergo a substitution reaction to form new substances, which may affect the surrounding environment and the objects in contact with it. Methionyl groups give the compound a certain lipophilicity, which may affect its distribution and metabolism in living organisms.
    Looking at its toxicity, chlorine-containing organic compounds often have certain toxicity. Chlorine atoms are highly electronegative and easily interact with biological macromolecules such as proteins and nucleic acids in living organisms. Or change the structure and function of biological macromolecules, thereby interfering with the normal physiological activities of cells. Such as entering the human body, or affecting the activity of enzymes, causing metabolic disorders. In addition, although methionyl is relatively common, its position in the structure of benzimidazole may change the toxic effect of the entire molecule. In the environment, this substance may cause harm to aquatic organisms, soil microorganisms, etc. Due to its lipophilicity, or easy accumulation in organisms, it is passed through the food chain and poses a potential threat to advanced organisms.
    In summary, the safety and toxicity of 6-chloro-5- (2,3-dichlorophenoxy) -2-methylthio-1H-benzimidazole need to be treated with caution. During its production, use and disposal, appropriate measures should be taken to reduce the potential harm to organisms and the environment.