What is the chemical structure of this product 6- (4-bromo-2-chlorophenamino) -7-fluoro-3-methyl-3H-benzimidazole-5-carboxylic acid (2-hydroxyethoxy) amide bisulfate?

This is a question about the chemical structure of a specific compound. The compound is 6- (4-hydroxy-2-methoxyphenylamino) -7-fluoro-3-methyl-3H-benzothiazole-5-carboxylic acid (2-methoxycarbonyl) benzyl ester.

Looking at its name, its structure can be analyzed according to the nomenclature of organic chemistry. " 6- (4-Hydroxy-2-methoxyphenylamino) ", indicating that a substituent is connected at the 6th position of the benzothiazole parent nucleus. This substituent is an aniline-derived part of 4-hydroxy-2-methoxy, which means that there is a hydroxyl group at the 4th position and a methoxy group at the 2nd position on the benzene ring of aniline, and it is connected to benzothiazole through a nitrogen atom." 7-Fluorine ", showing that there is a fluorine atom substitution at the 7th position of the benzothiazole parent nucleus." 3-Methyl-3H-benzothiazole ", indicating that there is a methyl group at the 3rd position of the benzothiazole parent nucleus, and this is a 3H type (that is, the thiazole ring 5-Carboxylic acid (2-methoxycarbonyl) benzyl ester ", indicating that the benzothiazole parent nucleus is connected to a carboxylic acid at 5 positions, and the carboxylic acid is estered with 2-methoxycarbonyl benzyl alcohol.

Its chemical structure is roughly as follows: benzothiazole as the core, 6-position with a specific aniline substituent, 7-position with a fluorine atom, 3-position with a methyl group, and 5-position with an ester group formed by 2-methoxycarbonyl benzyl alcohol and carboxylic acid. This structure covers benzene rings, thiazole rings, and various substituents. Each part is connected at a specific position according to the naming rules, forming the unique chemical structure of the compound.

What are the main uses of 6- (4-bromo-2-chlorophenamino) -7-fluoro-3-methyl-3H-benzimidazole-5-carboxylic acid (2-hydroxyethoxy) amide bisulfate?

6 - (4 - hydroxyl - 2 - mercaptophenoxy) - 7 - fluoro - 3 - methyl - 3H - benzopyrazole - 5 - carboxylic acid (2 - methoxy) benzyl ester hydrochloride, this compound has a wide range of uses. In the field of medicine, it may be a key drug intermediate, which is converted into a drug for the treatment of specific diseases through a series of reactions. For example, when developing drugs for certain inflammatory or nervous system diseases, it participates in the reaction by virtue of its structural properties to build active molecules and bring good news to patients.

In the field of materials science, or can participate in the synthesis of materials by virtue of its unique chemical structure and properties. Like the preparation of polymer materials with special optical and electrical properties, it injects vitality into the innovation and development of materials and promotes progress in related fields.

In organic synthetic chemistry, it serves as an important synthetic building block for chemists to build complex organic molecular structures. Through various chemical reactions, many organic compounds with novel structures and unique functions are derived, which opens up new ideas for organic synthetic chemistry, enriches the variety of compounds, and develops a reserve material base for various fields.

What is the synthesis method of 6- (4-bromo-2-chlorophenamino) -7-fluoro-3-methyl-3H-benzimidazole-5-carboxylic acid (2-hydroxyethoxy) amide bisulfate?

To prepare 6 - (4 - hydroxy - 2 - methoxyacetophenone) - 7 - methoxy - 3 - methyl - 3H - indolopyridine - 5 - carboxylic acid (2 - fluoroethoxy) benzyl ester hydrochloride, the synthesis method can be carried out according to the following steps.

First take appropriate starting materials, such as acetophenone compounds containing specific substituents, use it as a group, through hydroxylation reaction, introduce hydroxyl groups, and obtain intermediates of 4 - hydroxy - 2 - methoxyacetophenone. This step requires careful selection of reaction conditions, such as temperature, pH, etc., so that the reaction is smooth and the purity of the product is maintained.

Next, the intermediate is combined with the indolopyridine precursor containing a specific structure. In the meantime, suitable catalysts may be needed to promote the condensation of the two to obtain 6- (4-hydroxy- 2-methoxyacetophenone) -7-methoxy-3-methyl-3H-indolopyridine key intermediate. During the reaction, the choice of solvent is also important, and different solvents may affect the reaction rate and product configuration. < Br >
Then, this key intermediate is carboxylated, and a carboxyl group is added to obtain a carboxyl-containing indolopyridine compound. This carboxylation method, or the classic carboxylation reagent, is operated according to the specifications to introduce the carboxyl group into the target position precisely.

Then take the benzyl alcohol containing 2-fluoroethoxy group and make it esterified with the above carboxyl-containing indolopyridine compound to form 6- (4-hydroxy- 2-methoxyacetophenone) -7-methoxy-3-methyl-3H-indolopyridine-5-carboxylic acid (2-fluoroethoxy) benzyl ester. During the esterification process, proceed to the right to promote the reaction, or use the method of removing water to increase the yield of the product.

Finally, hydrochloric acid is used to react with it to form 6- (4-hydroxy-2-methoxyacetophenone) -7-methoxy-3-methyl-3H-indolopyridine-5-carboxylic acid (2-fluoroethoxy) benzyl ester hydrochloride. In this salt formation step, the amount of hydrochloric acid and the reaction time need to be controlled to make the product pure and meet the required specifications. After each step of the reaction, the purity and structure of the product should be measured by suitable analytical methods, such as chromatography and spectroscopy, to ensure that the synthesis path is correct.

What are the physical and chemical properties of 6- (4-bromo-2-chlorophenamino) -7-fluoro-3-methyl-3H-benzimidazole-5-carboxylic acid (2-hydroxyethoxy) amide bisulfate?

6 - (4 - hydroxyl - 2 - methoxyaniline) - 7 - fluoro - 3 - methyl - 3H - indolopyridine - 5 - carboxylic acid (2 - methoxycarbonyl) benzyl ester hydrochloride, this physical property is complex, and it has various properties of organic compounds.

Its physical properties, mostly solid at room temperature, are special because the molecule contains many polar and non-polar groups, resulting in its solubility. Polar carboxyl, methoxycarbonyl and amino groups enhance their solubility in polar solvents such as alcohols and ketones; while non-polar parts such as benzyl, methyl, and fluorine atoms also make them soluble in non-polar solvents such as toluene and dichloromethane. Due to the complex intermolecular forces caused by molecular structure, the melting point and boiling point depend on the strength of intermolecular interactions, including hydrogen bonds, van der Waals forces, etc. The exact value needs to be determined experimentally.

In terms of chemical properties, carboxyl groups are acidic and can neutralize with bases to form corresponding carboxylic salts, participate in esterification reactions, and form esters with alcohols under the action of catalysts. Methoxycarbonyl groups are chemically active and can undergo reactions such as hydrolysis and alcoholysis. Amino groups are alkaline and can react with acids to form salts, participate in nucleophilic substitution reactions, and react with halogenated hydrocarbons and other electrophilic reagents to introduce new groups. The aromatic ring structure is stable and can undergo electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Due to the influence of the substituents on the ring, the reactivity and positional selectivity are unique. The complex structure of the substance endows it with various physical and chemical properties, which are of important research and application value in the fields of organic synthesis and medicinal chemistry.

What is the application prospect of 6- (4-bromo-2-chlorophenamino) -7-fluoro-3-methyl-3H-benzimidazole-5-carboxylic acid (2-hydroxyethoxy) amide bisulfate in the market?

There are chemical substances today, called 6- (4-hydroxy-2-mercaptophenoxy) -7-ene-3-methyl-3H-indolopyridine-5-carboxylic acid (2-methoxy) benzyl ester phosphate. According to its name, it is complicated and obscure, like a book from heaven.

The application prospects of this product in the market are really thought-provoking. In the field of medicine today, research and development are advanced, and new and efficient drugs are pursued. These compounds may have unique pharmacological activities. Or it can be used as a ligand for potential drug targets. With its special structure, it can precisely act on specific proteins or enzymes in the body to regulate the physiological function of the body, treat difficult diseases such as tumors and neurodegenerative diseases, or it can emerge.

In the field of materials science, there are also opportunities. Special groups in its structure may endow materials with unique optical, electrical, and thermal properties. If it is used to make optoelectronic devices, it may optimize performance, improve luminous efficiency and conductivity, and contribute to the miniaturization and efficiency of electronic devices.

However, its application is also constrained. The synthesis method may be complicated and expensive, limiting mass production. And its biological safety and environmental impact are unknown, which needs to be further studied. If used in medicine, long-term toxicity and side effects need to be carefully investigated; for materials, degradation and residues in the environment after disposal also need to be considered.

In short, 6- (4-hydroxy-2-mercaptophenoxy) -7-ene-3-methyl-3H-indolopyridine-5-carboxylic acid (2-methoxy) benzyl ester phosphate has potential, but if it wants to show its skills in the market, it still needs unremitting research by researchers, breaking the synthesis problem, and understanding the safety impact, it is expected to become a practical treasure.