5 Trifluoromethyl 1h Benzoimidazole 2 Carboxylicacid
quinoline thiophene imidazole thiazole

5-TRIFLUOROMETHYL-1H-BENZOIMIDAZOLE-2-CARBOXYLICACID

    Specifications

    HS Code

    580517

    Chemical Formula C9H5F3N2O2
    Molar Mass 230.143 g/mol
    Appearance Solid (presumably, based on common benzoimidazole - carboxylic acid derivatives)
    Solubility In Water Low (aromatic and fluorinated carboxylic acid, typical of non - polar groups reducing water solubility)
    Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF (due to carboxylic acid and polar ring)
    Pka The carboxylic acid group would have a pKa around 3 - 5 (typical for aromatic carboxylic acids)
    Stability Stable under normal conditions, but sensitive to strong bases (due to carboxylic acid group) and strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 5-TRIFLUOROMETHYL-1H-BENZOIMIDAZOLE-2-CARBOXYLICACID supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 5-trifluoromethyl-1H-benzimidazole-2-carboxylic acid?
    5-Triethylmethyl-1H-benzopyrrole-2-carboxylic acid, its physical properties are as follows:
    This compound is mostly crystalline solid at room temperature, and the texture is relatively fine, just like the microcrystalline polymerization of nature. Looking at its color, it is often white to off-white, pure and free of variegated colors, just like the snow that falls at the beginning of winter, radiant and white, reflecting the natural and simple brilliance.
    When it comes to smell, the smell it emits is slight, close to the sniff, and there is a faint special smell, neither rich fragrance nor pungent smell. It is like a subtle smell hidden in nature, and you need to be careful to detect it. < Br >
    Its melting point is quite critical, about [X] ° C. Under this temperature, it is as stable as a rock, maintaining a solid state shape, orderly arrangement of lattice, and stable interaction between molecules; and once the melting point is approached, the lattice structure gradually loosens, the thermal movement of molecules intensifies, and then slowly melts from solid to liquid, just like ice and snow meet warm sun, quietly changing form.
    In addition, its solubility also has characteristics. In water, it is hard to find traces, just like swimming fish entering water, almost insoluble, because of the characteristics of molecular structure, and the interaction with water molecules is weak. However, in organic solvents such as ethanol and dichloromethane, it can gradually melt into them, such as ink-dyed water, showing good solubility, which is due to the formation of suitable interaction forces with organic solvent molecules, which promotes the dissolution process.
    In addition, density is also one of its physical properties, about [X] g/cm ³, giving it a unique relationship between mass and volume. In various reactions and practical applications, this property also plays a role that cannot be ignored, affecting the distribution and behavior of substances in the system.
    These various physical properties are intertwined to form the unique physical appearance of 5-triethyl-1H-benzopyrrole-2-carboxylic acid, which lays the foundation for its research and application in the field of chemistry.
    What are the chemical synthesis methods of 5-trifluoromethyl-1H-benzimidazole-2-carboxylic acid?
    To prepare 5-triethylamino-1H-indole-2-carboxylic acid, the following methods can be followed.
    First, indole is used as a group and is converted in multiple steps. First, indole is reacted with a reagent containing triethylamino under specific conditions, and triethylamino is introduced. This step requires selecting a suitable solvent and catalyst, controlling temperature and reaction time, so that the reaction can proceed in the desired direction. Then, the second position of the indole ring is modified, and a carboxyl group is added through a carboxylation reaction. The carboxylation is either introduced with carbon dioxide under alkali catalysis; or with a carboxyl-containing reagent, through nucleophilic substitution and other reactions, each step needs to be carefully controlled to separate and purify the intermediate product to increase the yield and purity of the target product.
    Second, phenylhydrazine and β-ketoate are used as starting materials to form indole rings through cyclization. This cyclization reaction requires a suitable reaction medium and catalytic system to effectively condensate and cyclize phenylhydrazine and β-ketoate. The cyclization product is then modified to introduce triethylamino and carboxyl groups. The introduction of triethylamino group can be selected according to its activity, nucleophilic substitution and other methods; the introduction of carboxyl group also follows the method of carboxylation described above, and each step should be optimized by the reaction conditions to separate the product to prevent side reactions and maintain the quality of the product.
    Third, it is prepared by the conversion of functional groups from commercially available compounds with similar structures. If there is a similar skeleton and a functional group is easily converted into triethylamino and carboxyl, the functional group can be first converted into triethylamino, and then a carboxyl group can be obtained through a series of reactions. If a functional group is gradually converted into a desired group through substitution, oxidation, reduction, etc., then this process requires detailed knowledge of the reactivity and selectivity of the raw material compound, and protection and de-protection strategies are used to prevent other functional groups from being disturbed, so as to achieve the purpose of efficient synthesis of 5-triethylamino-1H-indole-2-carboxylic acid.
    In which fields is 5-trifluoromethyl-1H-benzimidazole-2-carboxylic acid used?
    5-Triethylmethyl-1H-benzimidazole-2-carboxylic acid, this compound is used in many fields such as medicine, materials science, agricultural chemistry, etc.
    In the field of medicine, it often exhibits excellent biological activity. The structure of benzimidazole has good biological affinity and diverse pharmacological activities, and can be combined with many targets in organisms. For example, in the development of anti-cancer drugs, some compounds containing this structure can inhibit the proliferation and metastasis of cancer cells and other key links, providing new possibilities for solving cancer problems. In terms of antibacterial drugs, it can interfere with key physiological processes of bacteria, hinder bacterial growth and reproduction, effectively fight against a variety of pathogens, and protect human health.
    In the field of materials science, 5-triethylmethyl-1H-benzimidazole-2-carboxylic acid can be used as a functional monomer to participate in the synthesis of polymer materials due to its unique chemical structure. The materials produced by this method often have special properties, such as improving the thermal stability of the material, so that it can still maintain good performance in high temperature environments, and are used in high temperature electronic components, aerospace materials, etc. It can also enhance the optical properties of the material and be used to manufacture optical sensors, Light Emitting Diodes and other optoelectronic devices, expanding the scope of material applications.
    In the field of agricultural chemistry, this compound also plays an important role. It can be developed as a new type of pesticide, which has a high-efficiency repellent or poisoning effect on crop pests, and may have lower toxicity and better environmental compatibility than traditional pesticides, contributing to the development of green agriculture. At the same time, in terms of plant growth regulators, it can regulate the growth and development process of plants, such as promoting seed germination and improving crop resistance, etc., to help increase crop production and income.
    What is the market price of 5-trifluoromethyl-1H-benzimidazole-2-carboxylic acid?
    I have heard your inquiry about the market price of 5-triethylmethyl-1H-indolopyrazole-2-carboxylic acid. However, this is not easy to observe, and its price is subject to various factors, making it difficult to determine.
    First of all, the preparation of this product is complicated and requires skilled skills and special raw materials. From the procurement of starting materials to the precise control of each step of the reaction, it is all about cost. If raw materials are scarce and difficult to find, or the preparation process requires high-end equipment and harsh conditions, the cost will rise.
    Furthermore, the state of market supply and demand is also key. If there is a strong demand for this product in the fields of pharmaceutical research and development, chemical production, etc., but the supply is limited, the price will tend to rise; on the contrary, if there is little demand and overproduction, the price will easily drop.
    In addition, the price varies from region to region and manufacturer to manufacturer. Prosperous cities, due to convenient transportation and easy access to information, may have price advantages; remote places, costs may increase. Manufacturers vary in pricing due to different technical levels and management efficiency.
    To sum up, in order to know the exact market price of this product, it is necessary to study its preparation process, market supply and demand in detail, and consult more suppliers to compare quotations from different channels in order to obtain a relatively accurate price. However, it is difficult to sum up its specific market value at the moment.
    What are the safety and toxicity of 5-trifluoromethyl-1H-benzimidazole-2-carboxylic acid?
    5-Triethylmethyl-1H-benzofuran-2-carboxylic acid is an organic compound, and its safety and toxicity are extremely critical, which is related to life, health and environmental safety. According to the ancient saying:
    In terms of its safety, under normal use and appropriate dosage, if strictly toxicological evaluation, or no significant adverse effects on the organism. However, it needs to be handled with caution because of its specific chemical structure and properties, or latent risk. During operation, it is advisable to ensure good ventilation to prevent inhalation of its dust or vapor, and to avoid direct contact with skin and eyes. In case of inadvertent contact, rinse with plenty of water as soon as possible and seek medical attention as appropriate.
    As for toxicity, the toxicity of this compound needs to be considered in multiple aspects. Acute toxicity, or due to ingestion, inhalation or skin absorption of a certain amount of poisoning symptoms, such as nausea, vomiting, dizziness, fatigue, etc., serious or life-threatening. Chronic toxicity cannot be ignored. Long-term low-dose exposure may cause organ damage, dysfunction, or even cause gene mutation and carcinogenesis. In addition, it may be toxic to aquatic organisms and other ecological environments, affecting ecological balance.
    Therefore, the safety and toxicity of 5-triethylmethyl-1H-benzofuran-2-carboxylic acid should not be taken lightly. In all aspects of research and development, production and use, safety norms and standards should be strictly followed, and adequate threat and risk assessments should be carried out to ensure the safety of human health and the ecological environment.