5-methyl-2-phenyl-1H-imidazole

5-Methyl-2-phenyl-1H-imidazole is one of the organic compounds. It has unique physical properties, which are described as follows:
- ** Appearance properties **: Under normal conditions, it is mostly white to light yellow crystalline powder. Looking at it, it is delicate and shiny, like finely crushed jade, which may show a slightly radiant state under light. This appearance feature is crucial for the identification and preliminary understanding of the substance, and also helps to infer its purity and quality.
- ** Melting point **: about 155-158 ° C. When heated to this point, the substance gradually melts from a solid state to a liquid state. The characteristics of the melting point can be used to determine its purity. If the purity is high, the melting point range is narrow and approaches the standard value; if it contains impurities, the melting point may drop and the range becomes wider. This is an important indicator for identifying the purity of the compound.
- ** Solubility **: Slightly soluble in water, but soluble in organic solvents such as ethanol and dichloromethane. In water, it can only be dissolved in a small amount, and it seems to be repellent to water, but it can be miscible with organic solvents such as ethanol and dichloromethane, and it can be fused seamlessly. This solubility has a huge impact on the extraction, separation and reaction of compounds in different media, and can determine the location and conditions of the reaction.
- ** Stability **: Under normal conditions, it is quite stable. However, in case of strong oxidizing agents, strong acids, strong bases, etc., it is easy to react. In case of strong oxidizing agents, or being oxidized, the structure and properties will change; in case of strong acids and strong bases, or reactions such as hydrolysis and neutralization will occur. This stability is related to its storage and use conditions, and must be properly stored to avoid contact with the above substances.

5-Methyl-2-phenyl-1H-imidazole, this is an organic compound. It has unique chemical properties. In terms of physical properties, it often takes a solid form, but it varies depending on the surrounding environmental conditions, or has other states.
When it comes to solubility, it often has good solubility in organic solvents such as ethanol and dichloromethane. Due to the molecular structure, the non-polar part of methyl and phenyl groups is compatible with the non-polar part of organic solvents, and follows the principle of similar compatibility. However, in water, because of its strong overall non-polarity, the solubility is relatively limited.
In terms of chemical activity, the imidazole ring is the key active site. The lone pair of electrons on the nitrogen atom makes it alkaline and can react with acids to form corresponding salts. At the same time, due to the conjugated structure of the imidazole ring, the compound has a certain stability. However, under certain conditions, in case of strong oxidizing agents or high temperatures, the molecular structure may also be damaged.
Its methyl and phenyl groups also have a significant impact on the properties of the compound. Methyl as the power supply group can increase the electron cloud density of the imidazole ring, enhance its nucleophilicity, and make it easier to react with electrophilic reagents. The introduction of phenyl groups increases the steric resistance of the molecule, and because of its conjugate system, it can change the electron distribution of the molecule, affecting the reaction activity and selectivity. The chemical properties of 5-methyl-2-phenyl-1H-imidazoline are widely used in many fields such as organic synthesis and medicinal chemistry. They can be used as intermediates in organic synthesis and participate in many organic reactions, laying the foundation for the preparation of more complex compounds.

The common synthesis methods of 5-methyl-2-phenyl-1H-imidazole follow the path of organic synthesis. One method is to obtain a suitable nitrogen-containing and carbon-containing raw material through condensation reaction. For example, the aldehyde containing methyl group and phenyl group can be reacted with the nitrogen-containing reagent under specific conditions. In this process, the aldehyde group is condensed with the active hydrogen atom of the nitrogen-containing reagent, and after dehydration and other steps, it gradually forms the structure of an imidazole ring.
There are also those who use halogenated hydrocarbons as starting materials. The halogenated methyl benzene and the nitrogen-containing imidazole derivative undergo a nucleophilic substitution reaction under the catalysis of a base. The base can take away the hydrogen of the imidazole derivative, make it a nucleophilic reagent, and then replace it with the halogen atom of the halogenated hydrocarbon to introduce the required methyl and phenyl groups.
Furthermore, cyclization reaction can be used. Select a chain compound with suitable functional groups and cyclize it within the molecule to construct an imidazole ring. During the reaction, the reaction temperature, pH and catalyst conditions need to be carefully regulated. If the temperature is too high or too low, the reaction rate and product selectivity can be affected; if the pH is not suitable, the reaction may not proceed, or by-products may be formed; and a suitable catalyst can significantly speed up the reaction process and improve the yield.
Synthesis of this compound requires attention to the precise control of the purity of the raw material and the reaction conditions. The raw material is impure, easy to introduce impurities, which affects the quality of the product; a slight deviation in the reaction conditions may also reduce the yield or generate other isomers. Therefore, the experimenter needs to operate carefully and be skilled in regulation to obtain the ideal synthesis effect.

5-Methyl-2-phenyl-1H-imidazole is useful in various fields. This compound, in the field of medicine, is often a key raw material for the creation of new drugs. Due to its unique chemical structure, it can be combined with many targets in the body of organisms, so it can show a variety of biological activities, such as antibacterial, anti-inflammatory, anti-tumor and other effects. Doctors use it as a basis to study formulas, hoping to cure various diseases and save people from pain.
In the genus of materials science, 5-methyl-2-phenyl-1H-imidazole has also attracted much attention. It can be used as a special additive and integrated into polymer materials to improve the properties of materials. Such as enhancing the stability and heat resistance of materials, so that materials can maintain their inherent quality in extreme environments, so that they can be widely used in high-end technology industries such as aerospace and electronics, and help with sophisticated equipment and advanced skills.
Furthermore, in the field of organic synthesis, this imidazole compound is an important intermediary. Chemists can use it as a starting material and use various delicate reactions to construct organic molecules with complex structures and specific functions. Therefore, it expands the boundaries of organic synthesis, opens up new paths for the research and development of new materials and new drugs, and promotes the vigorous development of chemical science. It is of immeasurable value at both ends of industrial production and academic research.

5-Methyl-2-phenyl-1H-imidazole, this is a compound in organic chemistry. Its market price often varies depending on quality, purity, supply and demand, and the scale of trading.
In the context of ordinary chemical reagent trading, if it is a product of high purity and experimental grade, the price per gram may range from tens to hundreds of yuan. However, this is only a rough figure, and the actual price will change according to time.
If the purchase volume is quite large, such as the kilogram level, the supplier may give a discount due to economies of scale, and the average price per gram may be significantly reduced.
Furthermore, in the chemical raw material market, the price may fluctuate greatly due to many factors such as raw material cost, production process difficulty, market competition situation, etc.
In addition, the market in different regions may have different prices due to differences in logistics costs and tax policies. To know the exact market price, you need to consult the relevant chemical reagent suppliers, chemical product distributors, or check the recent transaction price on the chemical trading platform to get a more accurate price.