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What is the chemical structure of 5-Methoxy-2- ((S) - ((4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl) sulfinyl) -1H-benzimidazole
This is the English name for pantoprazole, and its chemical structure is as follows: The core of the compound is a benzimidazole ring, unsubstituted at the 1-H position. A sulfur-containing side chain is connected at the 2 position, and the sulfur atom on this side chain has a sulfoxide structure and has an S configuration. The sulfur atom of the sulfoxide is connected to a methyl group, which is in turn connected to 4-methoxy-3,5-dimethyl-2-pyridyl. Methoxy substitution is present at the 5 position. Its chemical structure can be depicted as follows: with a benzimidazole ring as the base, groups such as sulfur-containing side chains and methoxy groups are connected through specific chemical bonds, and each atom and group is arranged according to a predetermined rule, thus forming the unique chemical structure of pantoprazole, which endows it with specific chemical and pharmacological properties.
What are the main uses of 5-Methoxy-2- ((S) - ((4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl) sulfinyl) -1H-benzimidazole
5 - Methoxy - 2 - ((S) - ((4 - methoxy - 3,5 - dimethyl - 2 - pyridinyl) methyl) sulfinyl) -1H - benzimidazole, which is the chemical name of pantoprazole. Its main uses are quite extensive, and it is a good medicine for treating digestive system diseases in the medical system.
The diseases of the digestive system, such as gastric ulcer, duodenal ulcer, reflux esophagitis, etc., are caused by excessive gastric acid secretion or damage to the defense mechanism of the gastric mucosa. As a proton pump inhibitor, pantoprazole is like a loyal guardian. It can specifically act on the proton pump of gastric parietal cells, inhibiting the final link of gastric acid secretion, thereby effectively reducing the amount of gastric acid secretion. In this way, the acidity in the stomach can be greatly reduced, creating a good repair environment for the damaged gastric and intestinal mucosa, helping it heal ulcers, and relieving pain and heartburn caused by gastric acid irritation.
In the case of reflux esophagitis, gastric acid reflux to the esophagus, corroding the esophageal mucosa, and patients often feel heartburn and chest pain. By inhibiting gastric acid secretion, pantoprazole can effectively reduce the damage of reflux gastric acid to the esophageal mucosa, relieve symptoms, and help the esophageal mucosa return to normal.
In addition, pantoprazole also plays an important role in the treatment of Helicobacter pylori infection. Helicobacter pylori infection can easily cause gastritis, gastric ulcer and other diseases. Clinical combination regimens are often used. Pantoprazole works in tandem with antibiotics and other drugs to improve the eradication rate of Helicobacter pylori and reduce the possibility of disease recurrence. Because it can create a low-acid environment that is not conducive to the survival of Helicobacter pylori and enhance the antibacterial activity of antibiotics, the two complement each other and play a role in treatment.
What is the market outlook for 5-Methoxy-2- ((S) - ((4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl) sulfinyl) -1H-benzimidazole?
Today, there are 5-methoxy-2- ((S) - ((4-methoxy-3,5-dimethyl-2-pyridyl) methyl) sulfinyl) -1H-benzimidazole, and its market prospects are related to many aspects. This substance has great potential in the field of medicine, and may be used to develop new drugs for the treatment of gastrointestinal diseases. Looking at today's pharmaceutical market, there are many patients with gastrointestinal diseases, and there is a strong demand for related therapeutic drugs. If this is used as a key ingredient to develop new drugs, it may be able to meet this huge market demand, and the prospects are promising.
However, there are also challenges in its market path. From the perspective of R & D, the development of new drugs is time-consuming and expensive, and many clinical trials are required to prove their safety and effectiveness. This process is difficult and full of uncertainty. Furthermore, the pharmaceutical market is fiercely competitive, and similar or alternative drugs already exist. To stand out, it is necessary to demonstrate unique advantages, such as better efficacy and fewer side effects.
In addition, regulations and policies strictly regulate pharmaceutical products. Products must meet many regulatory requirements when they are marketed, and compliance costs are quite high. If we can overcome the research and development problems, meet the regulations, and highlight our advantages, 5-methoxy-2- ((S) - ((4-methoxy-3,5-dimethyl-2-pyridyl) methyl) sulfinyl) -1H-benzimidazole may be able to gain a place in the market, and the prospects are promising; conversely, if we cannot meet the challenges, the market development may be limited.
What is the production process of 5-Methoxy-2- ((S) - ((4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl) sulfinyl) -1H-benzimidazole
5-Methoxy-2- ((S) - ((4-methoxy-3,5-dimethyl-2-pyridyl) methyl) sulfinyl) -1H-benzimidazole is an important organic compound. Its production process is quite complicated, and it needs to be refined by ancient methods and various steps to obtain it.
Bear the brunt and choose suitable starting materials. It is necessary to select high-quality benzimidazole derivatives and pyridine compounds containing specific substituents, both of which are the basis for synthesis. These two raw materials must be carefully purified and impurities removed before they can be used.
Then, the key reaction step is carried out. First, the benzimidazole derivative is reacted with an appropriate reagent, and the methoxyl group is introduced at a specific position. This step requires temperature control and time control to achieve accurate substitution. Then the compound containing pyridine is inserted and the two are connected through a condensation reaction. This condensation method, or a catalytic agent, helps the reaction to be smooth.
Then, the sulfinyl structure is formed. This process requires careful oxidation to obtain the sulfinyl group of the (S) -configuration. When oxidizing, the reaction conditions need to be strictly monitored, because the accuracy of the configuration is related to the activity of the product.
In the meantime, after each step of the reaction, separation and purification must be performed. Either chromatography or crystallization techniques are used to purify the product and remove impurities. After layer-by-layer steps and fine operation, high-purity 5-methoxy-2 - ((S) - (4-methoxy-3,5-dimethyl-2-pyridyl) methyl) sulfinyl) -1H -benzimidazole can be obtained. The whole process requires the heart of a craftsman and fine control to obtain satisfactory results.
5-Methoxy-2- ((S) - ((4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl) sulfinyl) -1H-benzimidazole
5-Methoxy-2- ((S) - (4-methoxy-3,5-dimethyl-2-pyridyl) methyl) sulfinyl) -1H-benzimidazole, which is the chemical name of omeprazole. Omeprazole-related drug products are quite rich and play a key role in the field of medicine.
Many proton pump inhibitor drugs use omeprazole as the core component or are closely related to it. Common ones are omeprazole enteric-coated capsules, which are commonly used in clinical medicine and are mostly used to treat gastric ulcers, duodenal ulcers, reflux esophagitis and other diseases. Its mechanism of action is to specifically act on gastric parietal cells, inhibit gastric acid secretion, help ulcer healing and relieve gastric acid-related discomfort symptoms.
There are also omeprazole magnesium enteric-coated tablets, which are also widely used in various diseases caused by excessive gastric acid by inhibiting gastric acid secretion. It can be released slowly in the gastrointestinal tract, prolonging the efficacy and more effectively controlling gastric acid levels.
In addition, there is omeprazole sodium for injection, which is suitable for patients who are not suitable for oral administration, such as severe gastrointestinal ulcers accompanied by bleeding and other emergency situations. Through intravenous injection, it can quickly exert the effect of suppressing gastric acid, stabilize the condition, and strive for treatment opportunities for patients.
Although the above drug products are based on omeprazole, there may be differences in dosage form, applicable population, usage and dosage. In clinical use, doctors should choose reasonably according to the patient's specific condition and individual differences, so as to achieve the best therapeutic effect and ensure the safety of medication.