5 Methoxy 1h Benzimidazole 2 Thiol
quinoline thiophene imidazole thiazole

5-methoxy-1H-benzimidazole-2-thiol

    Specifications

    HS Code

    104498

    Chemical Formula C8H8N2OS
    Molecular Weight 180.227 g/mol
    Appearance Solid
    Melting Point ~290 - 295 °C
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Odor Odorless or faint sulfur - like odor
    Density Approx. 1.3 - 1.4 g/cm³
    Pka Value Around 7 - 8
    Stability Stable under normal conditions, may decompose on heating or in contact with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

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    What is the main use of 5-methoxy-1H-benzimidazole-2-thiol?
    5-Methoxy-1H-indole-2-formamide has a wide range of uses. In the field of medicine, it is often used as a key intermediate to synthesize many drugs with unique effects. Due to its special chemical structure, it can participate in a variety of chemical reactions, build complex active molecules, and then develop effective therapeutic drugs for specific diseases.
    In the field of organic synthesis, 5-methoxy-1H-indole-2-formamide is also an extremely important raw material. With its structural properties, chemists can transform it into various organic compounds with novel structures and unique functions by ingeniously designing reaction routes. This helps to expand the variety of organic compounds, promote the progress of organic synthetic chemistry, and provide a rich and diverse material basis for many fields such as materials science and drug research and development.
    In the field of materials science, some compounds synthesized on this basis may have special optical and electrical properties. These properties make them show potential application value in fields such as photoelectric materials and sensor materials. For example, it is possible to develop sensor materials that are sensitive to specific substances or physical quantities, and rely on their specific interaction with the target to achieve accurate detection of specific components in the environment; or to develop photoelectric materials with special luminescence properties, which can be applied to new display technologies and other fields, injecting new impetus into the development of related industries.
    What are the synthesis methods of 5-methoxy-1H-benzimidazole-2-thiol?
    The synthesis method of 5-methoxy-1H-indole-2-formamide, according to the ancient method of "Tiangong Kaiwu", has the following kinds:
    First, indole is used as the initial material. First, indole meets an appropriate amount of methylating reagents. With the help of appropriate temperature and catalyst, the two interact to obtain 5-methoxy indole. This process requires careful temperature control and time control, and the reaction state is observed to ensure the purity of the product. Then, 5-methoxy indole is co-located with the formylation reagent, and accompanied by suitable reaction conditions, such as specific solvents and temperatures, to make it formylated, and finally 5-methoxy-1H-indole-2-formamide is obtained. This way focuses on the accuracy of each step of the reaction, the proportion of reagents, and the choice of conditions are all about success or failure.
    Second, choose the appropriate nitrogen-containing heterocyclic precursor as the starting point. Let the precursor undergo a series of ingenious reactions, first introducing methoxy groups, and then undergoing specific transformations to add formamide groups. This path requires a thorough understanding of the characteristics of nitrogen-containing heterocycles, and clever use of various reactions, such as nucleophilic substitution, electrophilic substitution, etc. During the reaction, reagents and solvents should be carefully selected, and the reaction temperature and duration should be precisely adjusted according to the structure of the precursor, in order to follow this path and synthesize the target product.
    Third, build a skeleton from the basic organic compound. Based on carbon sources and nitrogen sources, the structure of 5-methoxy-1H-indole-2-formamide is gradually built through multiple steps of reaction. This is a complicated method, and each step needs to be controlled in sequence, so that the carbon chain, nitrogen group, etc. are connected and converted in sequence. Each step requires careful selection of reaction conditions to ensure that the reaction proceeds as expected. For example, the cyclization reaction requires the selection of appropriate catalysts and reaction environments in order to successfully synthesize the product after multiple steps.
    All synthesis methods have their own wonders and difficulties. Among the ancient methods, the observation of the reaction and the control of the conditions all rely on the experience and wisdom of the craftsman. People today can use the ancient methods to use modern technology and knowledge to make the synthesis more accurate and efficient.
    What are the physical and chemical properties of 5-methoxy-1H-benzimidazole-2-thiol?
    5-Methyl-1H-indole-2-carboxylic acid is an organic compound with specific physical and chemical properties.
    Among its physical properties, its appearance is mostly crystalline powder, which is easy to store and transfer, because its powder particles are small, tightly packed, and take up little space. From the perspective of melting point, it is generally in a specific temperature range, and its purity can be judged by melting point measurement. If the purity is high, the melting point range is narrow and close to the theoretical value; if the purity is low, the melting point range is wide and low.
    In terms of chemical properties, 5-methyl-1H-indole-2-carboxylic acids contain carboxylic groups, which are acidic and can neutralize with bases to form corresponding carboxylic salts and water. For example, when reacted with sodium hydroxide, 5-methyl-1H-indole-2-carboxylic acid and sodium water are formed. At the same time, carboxylic groups can participate in esterification reactions, which react with alcohols under acid catalysis to form ester compounds, which are used in organic synthesis to construct new compound structures and enrich the variety of compounds. In addition, the indole ring of this substance has certain aromatic properties and can undergo electrophilic substitution reactions, such as halogenation, nitrification, etc., which can introduce other functional groups on the indole ring to expand its chemical properties and application range. Due to its special structure, it is often used as a key intermediate in the field of medicinal chemistry to synthesize drug molecules with specific biological activities, providing an important basis for the development of new drugs.
    In which fields is 5-methoxy-1H-benzimidazole-2-thiol used?
    5-Methoxy-1H-indole-2-carboxylic acid, which is used in many fields such as medicine and chemical industry.
    In the field of medicine, it can be used as a key intermediate in drug synthesis. Many biologically active compounds need to be used as basic raw materials during synthesis. Take some anti-tumor drugs as an example, 5-methoxy-1H-indole-2-carboxylic acids can participate in their complex molecular construction process. By means of organic synthesis, its structure is modified and modified, which can endow the obtained compound with unique pharmacological activity, help the drug to better act on tumor cells, inhibit their proliferation, or induce their apoptosis, and open up new paths for the research and development of anti-tumor drugs.
    In the chemical industry, it also shows important value. In the preparation of fine chemical products, it is often used as a starting material for the synthesis of organic compounds with special structures. The synthesis of some high-performance dyes, fragrances and other products will introduce specific functional groups with the help of the special structure of 5-methoxy-1H-indole-2-carboxylic acid, so that the product has better performance. For example, the synthesis of new dyes with high color fastness and unique color, or fragrances that emit a unique aroma and last for a long time, etc., contribute to the diversified development of chemical products.
    In addition, in the field of materials science, with the increase in demand for new functional materials, 5-methoxy-1H-indole-2-carboxylic acids are gradually emerging. Researchers try to introduce them into the synthesis system of polymer materials, hoping to endow materials with special properties such as light response and biocompatibility, providing new ideas and approaches for the development of new smart materials and biomedical materials.
    What is the market prospect of 5-methoxy-1H-benzimidazole-2-thiol?
    5-Methoxy-1H-indole-2-carboxylic acid, which is in the market, has a promising future. Looking at the field of pharmaceutical research and development today, the search for many innovative drugs often relies on compounds with unique structures. It shows great potential in the development of drugs for neurological diseases. Due to its unique chemical structure, it may be able to precisely regulate the metabolism and transmission of neurotransmitters, and is expected to become a key component in the treatment of difficult diseases such as Parkinson's and Alzheimer's.
    In the field of materials science, 5-methoxy-1H-indole-2-carboxylic acids have also emerged. Due to its specific electronic properties and intermolecular forces, it can be used to create new functional materials. Such as organic semiconductor materials, which are expected to improve the electrical conductivity and stability of materials, and contribute to the miniaturization and efficiency of electronic devices.
    Furthermore, in the agricultural field, such compounds may be used as raw materials for new pesticides or plant growth regulators. The uniqueness of its structure may endow the product with excellent biological activity, which can effectively resist pests and diseases, and at the same time promote the healthy growth of plants, contributing to the sustainable development of agriculture.
    The demand for this product in the city is steadily increasing with the deepening and expansion of research in various fields. The production process is also becoming more and more mature, and the cost can be gradually controlled, making it more competitive in the market. Over time, 5-methoxy-1H-indole-2-carboxylic acid will surely shine in many fields and create brilliant market performance.