5-Iodo-2-Methyl-1H-Benzo[D]Imidazole

5-Iodine-2-methyl-1H-benzo [D] imidazole has a wide range of uses. In the field of medicine, this compound is often the key raw material for the creation of new drugs. The coinbenzimidazole structure has a variety of biological activities, such as antibacterial, antiviral, anti-tumor and other effects. 5-Iodine-2-methyl-1H-benzo [D] imidazole has been modified and modified to accurately target specific biomolecules in the body, interfering with disease-related physiological processes, and achieving therapeutic purposes.
In the field of materials science, it also has good performance. It can be used as a building block of functional materials to prepare materials with special optical and electrical properties. For example, by introducing specific substituents, its photoelectric properties can be regulated, and it can be used in organic Light Emitting Diodes (OLEDs), solar cells and other fields to improve the efficiency and stability of devices.
Furthermore, in the field of chemical research, 5-iodine-2-methyl-1H-benzo [D] imidazole is often used as an important organic synthesis intermediate. Chemists can use this to derive compounds with more complex structures and more specific functions through various chemical reactions, expanding the boundaries of organic synthesis chemistry and laying the foundation for exploring new substances and properties.
In summary, 5-iodine-2-methyl-1H-benzo [D] imidazole plays a pivotal role in many fields such as medicine, materials and chemical research, and has a significant role in promoting the development of related fields.

5-Iodine-2-methyl-1H-benzo [D] imidazole, this is an organic compound. Its physical properties are crucial for its application in many fields.
First, the appearance is usually solid, but the specific appearance may vary depending on the purity and preparation method. Generally speaking, the pure one is usually white to light yellow crystalline powder with a more delicate texture.
Besides the melting point, this compound has a specific melting point, which is between 200-220 ° C. The melting point is one of the important indicators for the identification of this substance. By measuring the melting point, its purity can be preliminarily determined. If the melting point of the sample is consistent with the theoretical value and the melting range is narrow, it often means that the purity is high; on the contrary, if the melting range is wide and deviates from the theoretical value, it may contain impurities.
Its solubility cannot be ignored. In common organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), there is a certain solubility. In dichloromethane, it can be well dissolved at room temperature to form a clear solution. This property makes it easy to participate in various reactions as a reactant in organic synthesis, and dichloromethane is volatile and easy to remove after the reaction. In water, its solubility is very small, because its molecular structure lacks groups that strongly interact with water molecules, and most of them are hydrophobic parts, so it is difficult to dissolve in water.
In addition, the compound has a density of about 2.0 g/cm ³, which is relatively dense. Density is of reference significance in the separation, storage and transportation of substances. Greater density may make the substance occupy a relatively small space during storage, but its weight factor needs to be considered during transportation.
In summary, the physical properties of 5-iodine-2-methyl-1H-benzo [D] imidazole, including appearance, melting point, solubility and density, play an important guiding role in the preparation, purification and application of organic synthesis, materials science and other fields.

To prepare 5-iodine-2-methyl-1H-benzo [D] imidazole, the method is as follows:
First take o-phenylenediamine as the starting material, go through the acylation step, mix it with acetic anhydride, and under the appropriate temperature and reaction time, the two start an acylation reaction to obtain N-acetyl o-phenylenediamine. This step is designed to protect one of the amino groups of o-phenylenediamine from both participating in the reaction in the subsequent reaction, resulting in complicated products. Then, N-acetyl-o-phenylenediamine and iodomethane meet, and in an alkaline environment and suitable reaction conditions, an alkylation reaction occurs, and methyl groups are introduced at specific positions of acetyl-o-phenylenediamine to obtain 2-methyl-N-acetyl-o-phenylenediamine. In this step, the target methyl group is successfully introduced by the activity of iodomethane.
Then 2-methyl-N-acetyl-o-phenylenediamine is co-placed in the reaction system with an iodine source, such as potassium iodide and a suitable oxidizing agent. Under suitable reaction temperature, duration and catalytic conditions, the construction and iodization of benzimidazole ring can be achieved, and 5-iodine-2-methyl-1H-benzo [D] imidazole can be obtained. This step uses the energy of oxidizing agent to promote the conversion of iodine ions into active iodine species, and then electrophilic substitution occurs with benzimidazole ring, and iodine atoms are introduced at the target position.
Finally, the product needs to be separated and purified, and column chromatography, recrystallization method, etc. can be used. Column chromatography achieves the purpose of separation according to the different distribution coefficients of different substances in the stationary phase and the mobile phase; recrystallization method obtains a purified product by the different solubility of the product and impurities in a specific

I don't know what the price of 5-Iodo-2-Methyl-1H-Benzo [D] Imidazole is on the market. This is a fine chemical, and its price fluctuates greatly and is influenced by many factors.
First, the purity has a huge impact. If the purity is extremely high and almost perfect, it can be used for high-end scientific research experiments, and the price will be high; if the purity is slightly lower, it is only for general industrial use, and the price will be slightly lower.
Second, the trend of supply and demand is also the key. If the market demand is strong and the supply is scarce, merchants will raise the price in order to make a big profit; if the supply exceeds the demand, the price will drop in order to make a sale.
Third, the difficulty of production is also related. If the preparation of this product requires cumbersome processes and rare raw materials, the cost will be high, and the price will also increase; if the preparation is relatively simple, the price may be close to the people.
Fourth, the brand and source are different, and the price is also different. Produced by well-known large factories, the quality is guaranteed, and the price may be high; produced by small factories, although the price is low, the quality may not be satisfactory.
Therefore, in order to know the exact price range, it is necessary to carefully observe the current market dynamics, consult chemical product suppliers, trade platforms, or visit the chemical market in person, in order to obtain more accurate price information.

5-Iodine-2-methyl-1H-benzo [D] imidazole, this is a fine chemical, its storage conditions are crucial, related to its quality and stability. According to the ancient law, when storing things according to the following regulations.
First of all, a cool and dry place, this is the essence. This material is sensitive to nature and is afraid of moisture and heat. If it is in a warm and humid place, its molecular structure is easy to change, causing changes in properties and decay in efficiency. If it is a treasure in ancient times, it must be dry and cool to protect its quality.
Furthermore, it needs to be placed in a closed device. This substance is exposed to the air, and it is easy to intersect with various components, such as oxygen, water vapor, etc., causing chemical reactions and damaging its purity. Therefore, if you use a sealed device to hold it, it is like building a strong wall for it to protect it from external intrusion.
And avoid co-storage with strong oxidants, strong acids, strong bases, etc. When these substances meet with 5-iodine-2-methyl-1H-benzo [D] imidazole, such as dry wood and fire, it is prone to violent reactions, or the risk of combustion or explosion, which is unspeakable.
In addition, the storage place should be clearly marked, stating the name, characteristics and storage attention of this substance. In this way, everyone knows the risks, and they must be careful when operating to prevent accidental contact and ensure the safety of storage.
In general, the storage of 5-iodine-2-methyl-1H-benzo [D] imidazole must be cool, dry, sealed, avoid strong acid-base oxidants and clearly marked regulations to ensure its quality for later use.