5 Hydroxy 1 Beta D Ribofuranosyl 1h Imidazole 4 Carboxamide
quinoline thiophene imidazole thiazole

5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide

    Specifications

    HS Code

    158481

    Chemical Formula C8H12N4O5
    Molar Mass 244.205 g/mol
    Appearance White to off - white solid
    Solubility In Water Moderately soluble
    Melting Point 212 - 216 °C
    Pka Value 3.89 (for the imidazole nitrogen)
    Uv Absorption Peak Around 280 nm
    Chirality Has chiral center (beta - D - ribofuranosyl part)
    Isomeric Form Exists in specific ribofuranosyl isomeric form
    Biological Activity Involved in purine metabolism

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    General Information
    Where to Buy 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide in China?
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    Frequently Asked Questions

    As a leading 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide?
    5 - Hydroxy - 1 - β - D - ribofuranosyl - 1H - imidazole - 4 - carboxamide is also a chemical substance. To be clear, and to be described.
    Among this compound, imidazole is contained. For imidazole, it is a five-element nitrogen-containing compound with a dinitrogen atom residing in the compound. The first position above it is β-D-ribofuranosyl. Beta-D-ribofuranose, the sugar type, which has the shape of furanose, and the shape of β, the sugar group is located in the imidazole position with its terminal carbon atom.
    Furthermore, the imidazole position 4 is connected with a carboxyamide group. This carboxyamide group is formed from the carbonyl amino phase, and is located on the imidazole position 4 carbon. The 5th position has a group.
    In this way, 5 - Hydroxy - 1 - β - D - ribofuranosyl - 1H - imidazole - 4 - carboxamide is composed of imidazole core, 1-position β-D-ribofuran glycosyl, 4-position carboxamide group, and 5-position carboxamide group. In this case, each group is connected to each other, and together determine the properties of the compound.
    What are the main uses of 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide?
    5-Hydroxy-1 - β - D-nitrofuranosyl-1H-imidazole-4-formamide, this substance is widely used. In the field of medicine, it can be used as a key raw material for drug synthesis. Because it has a unique chemical structure, it can provide a basis for the creation of drugs to treat specific diseases. For example, in the development of antiviral drugs, its structural properties may help the drug to act precisely on the viral replication process, thereby inhibiting the reproduction of the virus.
    It also plays an important role in biochemical research. Researchers can use it to explore cellular metabolic pathways. Because it participates in specific biochemical reactions in cells, it can help scientists clarify the transformation and regulation mechanism of various substances in the metabolic process, which is of great significance in revealing the mysteries of life and solving difficult diseases.
    In food additives, it may also have applications. Due to its specific chemical properties, it can be added to food as a nutritional enhancer to supplement specific nutrients for the human body, enhance the nutritional value of food, and meet the nutritional needs of different populations.
    In addition, in the field of agriculture, it may play a role in plant growth regulation. By affecting specific physiological and biochemical processes in plants, it can regulate plant growth and development, or it can improve crop yield and quality, providing assistance for agricultural production. In short, 5-hydroxy-1 - β - D-ribosyl-1H-imidazole-4-formamide has shown important application value in many fields and has broad prospects.
    What are the physical properties of 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide?
    5-Hydroxy-1 - β - D-nitrofuran-1H-imidazole-4-formamide, this is an organic compound, its physical properties are particularly important, related to its application in various fields.
    Its appearance is often white to off-white crystalline powder, which is conducive to observation and identification, and is easy to handle and operate. Looking at it, its powder is fine and uniform, and the particle size is relatively consistent, just like finely ground jade powder, highlighting its purity.
    As for the melting point, it is between 170-175 ° C. The melting point is an inherent property of a substance, and this specific melting point range indicates the stability and consistency of its structure. When heated to this temperature range, the substance gradually converts from a solid state to a liquid state, just like ice and snow melting in the warm sun. This process is orderly, which proves the regularity of its internal structure.
    In terms of solubility, it is soluble in water, but difficult to dissolve in common organic solvents such as ethanol and ether. When dissolved in water, it is like a spring rain merging into the earth and quietly dispersing to form a uniform solution. In organic solvents, it is difficult to blend like oil droplets into water. This property stems from the difference in its molecular structure and the force between solvent molecules, which has a profound impact on its separation, purification and preparation processes.
    In addition, the compound has certain hygroscopicity. In a high humidity environment, like a sponge absorbing water, it can absorb moisture in the air, causing its own weight to increase, and even the shape may change, or it may change from a dry powder to a slightly moist lump. This hygroscopicity reminds you to pay attention to the ambient humidity when storing and using, and take proper protective measures to ensure the stability of its quality and performance.
    In summary, the physical properties of 5-hydroxy-1 - β - D-ribosyl-1H-imidazole-4-formamide, from appearance, melting point, solubility to hygroscopicity, are the key elements for in-depth understanding and rational use of this compound, which is of great significance in many fields such as chemical industry and medicine.
    What is 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide synthesis method?
    5-Hydroxy-1 - β - D-nitrofuranosyl-1H-imidazole-4-formamide is an important compound. Its synthesis method is quite complicated and delicate.
    In the past, this compound was often synthesized with a specific ribose derivative as the starting material. First, the furan ribose with a specific configuration was taken and its hydroxyl group was modified with an appropriate protective group to prevent the hydroxyl group from participating in the reaction for no reason and causing the reaction direction to deviate from the expected direction.
    Subsequently, the imidazole structural unit was introduced. Often through clever organic reactions, the nitrogen-containing heterocyclic precursor interacts with the ribose derivative. In this process, it is necessary to precisely regulate the reaction conditions, such as temperature, pH and reaction time, so that the imidazole ring can be connected to the ribose in the correct position to form the key glycosidic bond.
    The introduction of carboxylamide groups also requires careful design steps. Or through the appropriate functional group conversion of the intermediate, the intermediate containing carboxylamide group is first formed, and then the condensation reaction is carried out to react with ammonia or amine compounds to successfully introduce the carboxylamide group. After the
    reaction is completed, it is necessary to carefully remove the previously introduced protective groups to obtain pure 5-hydroxy-1 - β - D-ribosyl-1H-imidazole-4-formamide. This deprotection process also requires strict control of conditions to avoid damage to other parts of the target molecule. Every step of the synthesis requires fine operation and strict control to obtain this compound.
    5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide in what areas?
    5-Hydroxy-1 - β - D-nitrofuran-1H-imidazole-4-formamide is useful in many fields such as medicine and biochemistry.
    In the field of medicine, it has attracted much attention in the research and development of anti-tumor drugs. This compound can inhibit the proliferation of tumor cells by interfering with the metabolic pathway of tumor cells. For example, it can affect the synthesis of specific nucleotides in tumor cells, thereby destroying the replication of tumor cells' genetic material, making it difficult for them to continue to divide and grow. Some studies have applied pharmaceutical preparations containing this ingredient to specific tumor models, showing that the tumor volume is significantly reduced, providing a new path for the creation of anti-tumor drugs. < Br >
    In the field of biochemical research, it is an important bioactive substance and plays a key role in regulating the activity of many enzymes. It can be combined with specific enzymes to change the spatial conformation of enzymes, thereby affecting the rate of enzymatic reactions. In cell signaling research, it participates in key signaling pathways in cells, such as affecting the activity of certain protein kinases, regulating important processes such as cell growth, differentiation and apoptosis, and helping researchers gain insight into the mysteries of cell life activities.
    In the field of nutrition and health care, it may have potential effects. Studies have shown that appropriate intake of this substance may regulate human metabolism and enhance the body's antioxidant capacity. During human metabolism, harmful substances such as reactive oxygen species are produced, which may enhance the activity of antioxidant enzymes, remove such harmful substances, and maintain cellular health, which may be beneficial in preventing chronic diseases.