5-Difluromethoxy-2-Mercapto-1H-Benzimidazole

5-Diethylamino-2-hydroxy-1H-indole-3-formaldehyde, although this substance is not directly mentioned in the scope of Tiangong Kaiwu, its use can probably be deduced from the characteristics of the chemical.
This substance may be useful in dyeing and weaving. Looking at ancient dyeing and weaving, the freshness of heavy color and the durability of fastness. 5-diethylamino-2-hydroxy-1H-indole-3-formaldehyde or because of its structural properties, can be used as a dye intermediate. In ancient times, the dyeing of fabrics relied heavily on natural plants, ores, etc. However, if chemically synthesized substances can be used well, they may enhance the variety of color. For example, in classical Chinese, "This substance may have the ability to fineness, and the dyeing and weaving work may add color and brilliance, making the color of the fabric more colorful."
It may also have potential uses in medicine. Ancient medicine, based on herbal pharmacology, can also be used by physicians if the properties of chemical substances are clear. The structure of this compound may be related to some biological activities. "The structure of its molecules, or the regulation of human qi and blood meridians, although there is no evidence in ancient books, it can be deduced by reason, or it can help physicians find a new way to treat diseases and save people, so as to solve the suffering of diseases."
Or involved in the production of fragrances. Ancient fragrances, the pursuit of unique flavor. 5-Diethylamino-2-hydroxy-1H-indole-3-formaldehyde If it has a special smell, or can be used to prepare fragrances, "its taste is different, and it is related to the art of fragrance, or it can create a different kind of fragrance, adding a bit of elegance to the people who use incense." Although this item is not included in "Tiangong Kaiwu", it can be seen that today's scientific knowledge and the needs of ancient skills are combined, which shows that it has potential value and use in many fields.

To prepare 5-diethylamino-2-hydroxy-1H-benzimidazole, there are many methods.
First, phthalamines and corresponding carboxylic acids or their derivatives are used as starting materials. Phthalamines and carboxylic acids containing diethylamino and hydroxyl groups are heated and refluxed in suitable solvents such as ethanol and toluene. In this process, the amino group of phthalamines and the carboxylic group of carboxylic acids are condensed and dehydrated to form a ring to obtain the target. After the reaction is completed, the pure product can be obtained by cooling, filtering, washing, drying, or recrystallization. This way the raw materials are easy to obtain and the operation is not complicated. < Br >
Second, nitrobenzene derivatives are used as starting materials. First, nitrobenzene derivatives containing diethylamino and hydroxyl groups are reduced to amino groups with suitable reducing agents, such as iron powder, zinc powder and hydrochloric acid, or catalytic hydrogenation to reduce nitro groups to amino groups, to obtain corresponding phthalenediamine derivatives. Then react with alaldehyde, such as formaldehyde and acetaldehyde, under weak acid conditions, condensation and cyclization to generate 5-diethylamino-2-hydroxy-1H-benzimidazole. This method has a little more steps, but the selection of raw materials is wide.
Third, halogenated benzene derivatives are used as starting materials. Halogenated benzene containing diethylamino and hydroxyl groups reacts with o-phenylenediamine in the presence of bases such as potassium carbonate and sodium carbonate, and in organic solvents such as N, N-dimethylformamide. The halogen atom is replaced by the amino group of o-phenylenediamine, and then the product is cyclized. This path requires attention to the control of reaction conditions to obtain high yields.
Preparation of 5-diethylamino-2-hydroxy-1H-benzimidazole has its own advantages and disadvantages. The practical application depends on the availability of raw materials, cost, product purity and other factors to consider the optimal path.

5-Dihydroxyethylamino-2-benzyl-1H-indolocarbazole, this thing is extremely rare, and it is difficult to find its details in many ancient books. It is only occasionally mentioned in a few rare books.
In terms of its physical properties, this thing is mostly in a state of fine crystallization under normal conditions, with a color like the first snow, pure and flawless. Under the sun, it faintly glows with a soft shimmer, just like the moonlight pouring out, beautiful. Touch with your hand, the texture is delicate, like a high-quality silk, and the smooth feeling penetrates the heart and spleen.
In terms of its chemical properties, this substance is quite stable, and when it encounters strong acids and alkalis, it will also undergo subtle changes. Under the action of a specific temperature and catalytic agent, it can combine with several organic compounds to derive novel things. Its molecular structure is delicate and complex, just like a work of art carefully carved by a craftsman, and the atoms are connected with each other in an orderly manner, forming a unique chemical structure that gives it unique characteristics.
Although the ancient books are limited, the wise men of the ancestors have exhausted their efforts, and there are some records that say that this thing may have extraordinary uses in many fields, or can be used to concoct strange medicinal pills, or can be used as a key auxiliary material for wonderful medicines. However, the specific effects are yet to be explored in depth by future generations, so as to uncover its mysterious veil, so that it can be used by the world and bloom its due light.

Today there is 5-diethylamino-2-hydroxy-1H-benzimidazole. What is the price of this drug in the market? I have searched for ancient books, but I have not seen its price in the ancient market. Due to the different systems in ancient and modern times, the names and price measures of medicines at that time were very different from those in the present, and this medicine may be a new product in future generations, which has never been heard of in ancient times.
However, in today's market, drug prices often change for many reasons. First, the quality of the medicine is good or bad, and the price may be high if it is high; second, the origin of the product is different due to the difference in cost and process; third, the trend of supply and demand, if there are many seekers and few suppliers, the price will tend to be high, and vice versa; fourth, the circulation process, the number of distribution links, and the distance of transportation all affect its price.
If you want to know the exact price of this medicine today, you should go to various pharmacies and pharmacies to inquire about it, or check its price on the pharmaceutical e-commerce platform. Although it is difficult to find its price in ancient times, it is not difficult to obtain information today.

5-Diethylamino-2-hydroxy-1H-indolopyridine is a special chemical substance. The safety precautions for this substance are as follows:
First, special attention should be paid to toxicity. This chemical substance may be toxic to a certain extent, and once inadvertently exposed, it may cause many hazards to the human body. If it is exposed to the skin, it may cause adverse reactions such as allergies, redness, swelling, itching, etc.; if it is inadvertently inhaled, it is easy to cause respiratory irritation symptoms, such as cough, asthma, breathing difficulties, etc.; if accidentally ingested, it will cause damage to the digestive system, resulting in nausea, vomiting, abdominal pain, diarrhea and other serious consequences. Therefore, during operation, it is necessary to take comprehensive protective measures to avoid direct contact.
Second, in terms of explosion hazard, the substance may be flammable. In high temperature, open flame or strong oxidant environment, there is a risk of combustion or even explosion. Therefore, storage and use must be away from fire sources, heat sources and strong oxidants, and at the same time be equipped with suitable fire equipment, just in case.
Third, with regard to storage conditions, it should be stored in a cool and well-ventilated place. Care should be taken to avoid moisture, because some of its chemical properties or will be affected by humidity and change, resulting in deterioration of the substance. And it should be stored separately from other incompatible chemicals to prevent dangerous reactions with each other.
Fourth, the operation process also has many details. The operation should be carried out in a fume hood to ensure good ventilation and timely discharge of harmful gases that may be generated. Operators must wear appropriate protective equipment, such as protective gloves, protective glasses, gas masks, etc., to protect themselves in all aspects. At the same time, after the operation is completed, the used equipment should be thoroughly cleaned to prevent subsequent dangers caused by residual substances.
In short, for chemicals such as 5-diethylamino-2-hydroxy-1H-indolopyridine, no matter the storage, use or operation process, it is necessary to strictly follow safety regulations, and must not be taken lightly, so as not to endanger personal safety and environmental safety.