5 Difluoromethoxy 1h Benzoimidazole 2 Thiol
quinoline thiophene imidazole thiazole

5-Difluoromethoxy-1H-benzoimidazole-2-thiol

    Specifications

    HS Code

    313285

    Chemical Formula C8H6F2N2OS
    Molecular Weight 216.21
    Appearance Solid (usually a powder)
    Physical State At Room Temp Solid
    Melting Point Typically in a certain range (data needed for exact value)
    Solubility In Water Low solubility (hydrophobic nature)
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, DMF
    Pka Data needed for accurate value
    Logp Data needed for accurate value
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 5-Difluoromethoxy-1H-benzoimidazole-2-thiol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 5-difluoromethoxy-1H-benzimidazole-2-thiol?
    5-Dihydroxyacetyl-1H-indolocarbazole-2-phosphate, this is a special chemical substance. Its main uses are quite extensive, and from the perspective of "Tiangong Kaiji", it can be viewed from many aspects.
    In the field of medical inquiry, such compounds often have key effects. Due to their unique chemical structure, they may be able to combine with specific targets in organisms, thus showing the potential to regulate physiological functions. For example, in the study of certain diseases, it may be used as a lead compound to help researchers develop more effective therapeutic drugs to combat diseases such as cancer and neurological diseases. By precisely acting on the specific molecular pathways of diseased cells, it can inhibit the proliferation of cancer cells or repair damaged nerve cells, bringing hope for recovery to patients.
    In the field of biochemical research, 5-dihydroxyacetyl-1H-indolocarbazole-2-phosphate is also an important tool. Researchers often use its unique properties to deeply explore the signaling mechanism in cells. It can serve as a marker to help reveal the details of cell signaling in different physiological or pathological states, such as cell growth, differentiation, apoptosis and other key processes. By observing its behavior in cells, researchers can gain a clearer insight into the mysteries of life activities, laying the foundation for further understanding of the essence of life.
    In the field of materials science, it may also have potential applications. Due to its chemical properties, it may be treated by special processes and applied to the research and development of new functional materials. For example, it may endow materials with specific optical and electrical properties, so as to play a role in optoelectronic devices, sensors, etc. Or it may be able to prepare sensors with high sensitivity to specific substances, which can be used in environmental monitoring, food safety testing and other fields to help people better ensure the quality of life and safety.
    What are the synthesis methods of 5-difluoromethoxy-1H-benzimidazole-2-thiol?
    To prepare 5-% diethylamino-1H-indole-2-carboxylic acid, there are various methods.
    First, it can be obtained by starting with the corresponding indole derivative and reacting in multiple steps. First, ethylamino is introduced at a specific position of indole, which can be replaced by nucleophilic substitution. Select a suitable halogenated ethylamine and react with indole derivatives in a suitable base and solvent environment. The base can be selected from potassium carbonate or the like, and the solvent is N, N-dimethylformamide (DMF), which can help the reaction to proceed, enhance the activity of nucleophiles, and facilitate the access of ethylamino. After the successful introduction of ethylamino, a carboxyl group is constructed at the 2-position of indole. The Grignard reagent can be used to react with halogenated indoles as substrates to make Grignard reagents first, and then react with carbon dioxide to obtain carboxyl groups after hydrolysis, thereby obtaining 5-% diethylamino-1H-indole-2-carboxylic acid.
    Second, it can also start from simple aromatic hydrocarbons. After the Fu-gram reaction, a suitable substituent is introduced into the aromatic hydrocarbons to gradually build the backbone of indoles. For example, using benzene derivatives as raw materials, through the Fu-gram acylation reaction, a carbonyl-containing substituent is introduced. Then through a series of reactions such as reduction and cyclization, the indole structure is formed. After cyclization, ethylamino is introduced first, and then carboxyl is constructed according to the above-mentioned similar method. In the step of introducing ethylamino, in addition to nucleophilic substitution, if the substrate is suitable, the method of reductive amination can also be used to react with aldehyde or ketone and ethylamine under the action of reducing agents such as sodium borohydride derivatives to form carbon-nitrogen bonds.
    Third, the strategy of splicing with heterocyclic synthesizers can also be considered. The heterocyclic synthesizer containing indole partial structure is selected, and the fragment containing ethylamino and carboxyl precursors is spliced through a suitable reaction. For example, the coupling reaction catalyzed by transition metals, such as the coupling reaction catalyzed by palladium, can precisely connect each fragment. After subsequent modification and adjustment, the synthesis of 5-% diethylamino-1H-indole-2-carboxylic acid can also be achieved. < Br >
    All methods have advantages and disadvantages. In actual preparation, the appropriate method should be carefully selected according to factors such as the availability of raw materials, the difficulty of reaction conditions, the requirements of yield and purity.
    What are the physicochemical properties of 5-difluoromethoxy-1H-benzimidazole-2-thiol?
    Dihydrate acetoxy-1H-indolocarbazole-2-arsenic acid is an extraordinary thing, and its physical and chemical properties are particularly important. Let me explain in detail.
    Looking at its physical properties, dihydrate acetoxy-1H-indolocarbazole-2-arsenic acid is usually presented in a specific form. Under normal temperature and pressure, or in a solid state, its appearance may have a unique color and texture, or it may be in a crystalline state with a regular crystal form, which seems to hide mysteries in the refraction of light. The melting point of this substance is one of the key physical properties. It requires a specific temperature to convert from solid to liquid. The accurate determination of this temperature is of great significance to distinguish its purity and characteristics. In terms of solubility, it varies in different solvents. In polar solvents, it may have a certain ability to dissolve, but in non-polar solvents, it may be difficult to dissolve. This property is closely related to the molecular structure, and the polar part interacts with the solvent to affect its solubility.
    In terms of chemical properties, the chemical activity of dihydro acetoxy-1H-indolocarbazole-2-arsenic acid is also worth exploring. The specific functional groups contained in its molecular structure give it unique chemical reactivity. The acetoxy group may participate in the substitution reaction. Under suitable conditions, the acetyl group can be replaced by other groups, thereby deriving a variety of derivatives and expanding its application range. The structure of indole carbazole has certain aromatic and electron cloud distribution characteristics, which is easy to react with electrophilic reagents, or introduce new substituents on the benzene ring and indole ring. As for the arsenic acid part, because it contains arsenic, it has a certain acidity and can neutralize with bases to generate corresponding salts. This reaction not only affects its stability in different acid-base environments, but also in the preparation and application process, the control of acid-base conditions is crucial. In addition, the substance exhibits specific reaction behaviors in redox reactions or due to the valence state changes of some atoms in the structure, which provides possibilities for its application in many chemical reaction systems.
    The physicochemical properties of dihydrate acetoxy-1H-indolocarbazole-2-arsenic acid are complex and delicate. In-depth study of these properties can better control this substance and exert its potential value in many fields such as chemical industry and medicine.
    What is the price of 5-difluoromethoxy-1H-benzimidazole-2-thiol in the market?
    Today there is a question, what is the market price of 5-dihydroxyethylamino-1H-benzimidazole-2-carboxylic acid? This is a specific chemical in the field of fine chemicals.
    5-dihydroxyethylamino-1H-benzimidazole-2-carboxylic acid, its price fluctuations are really influenced by many factors. The first one is the cost of raw materials. The synthesis of this chemical requires specific starting materials. If the raw materials are difficult to obtain or the market supply is scarce, the price will rise, and the cost of 5-dihydroxyethylamino-1H-benzimidazole-2-carboxylic acid will also rise, which will increase the price.
    Furthermore, the simplicity of the production process is also the key. If the production process requires complex reaction steps, harsh reaction conditions, or high-end equipment and technology, the cost of such production will increase greatly, and the price in the market will be high.
    The situation of market supply and demand also deeply affects its price. If there is a strong demand for 5-dihydroxyethylamino-1H-benzimidazole-2-carboxylic acid in a certain field at a certain time, but the supply is limited, this is a seller's market, and the price tends to go up; on the contrary, if the supply is abundant and the demand is weak, the price is easy to go down.
    In addition, the price varies for different purity grades. High-purity 5-dihydroxyethylamino-1H-benzimidazole-2-carboxylic acid, due to the need for finer purification processes, the price is usually higher than that of ordinary purity.
    To know the exact price, you can consult chemical product suppliers, browse chemical product trading platforms, or inquire from industry insiders, so as to obtain more accurate price information.
    What are the safety and toxicity of 5-difluoromethoxy-1H-benzimidazole-2-thiol?
    5-Diethylamino-1H-indole-2-formonitrile, this substance is related to the chemical industry. In terms of safety, if it is not handled properly, it may pose a latent risk. From the perspective of chemical properties, this substance may react with certain chemical reagents. If it is not mixed properly, it may cause dangerous situations such as heat, combustion or even explosion. Therefore, when storing, it is necessary to strictly follow the chemical storage specifications, and place it in a cool, dry and well-ventilated place, away from fire sources and oxidants.
    When it comes to toxicity, this substance may affect organisms to varying degrees. There are various ways of exposure, such as skin contact, or skin irritation, redness, swelling, itching and other symptoms; if inadvertently inhaled, it may affect the respiratory tract, causing cough, asthma, etc.; if eaten by mistake, it will cause great damage to the digestive system, or cause vomiting, abdominal pain and other serious consequences.
    The ancients said: "The scourge of husband often accumulates in the slightest, but Zhiyong is mostly trapped in drowning." When dealing with such chemicals, do not take it lightly. The operating procedures need to be strictly followed, and the operators should be equipped with professional protective equipment, such as protective gloves, goggles, gas masks, etc., to reduce the risk of exposure. At the same time, the workplace needs to have perfect ventilation facilities and emergency treatment equipment, just in case. Only by treating it with such caution can we ensure the safety of personnel and the environment is not