Name | 5 - Aminoimidazole |
Molecular Formula | C3H5N3 |
Molar Mass | 83.09 g/mol |
Appearance | White to off - white solid |
Melting Point | 149 - 152 °C |
Solubility In Water | Soluble |
Solubility In Organic Solvents | Soluble in some polar organic solvents like ethanol |
Stability | Stable under normal conditions |
Odor | Odorless |
What is the chemical structure of 5-Aminoimidazole?
5 - Aminoimidazole is one of the organic compounds. Its chemical structure is quite unique, with an imidazole ring as the base, and an amino group (-NH 2) connected at the 5 positions on the ring. The imidazole ring has the structure of a five-membered nitrogen-containing heterocycle, composed of two nitrogen atoms and three carbon atoms. This ring is aromatic, and its chemical properties are active and rich due to the unique distribution of electron clouds in the ring. The amino groups connected at the 5 positions introduce basic properties to it, so that the compound can participate in a variety of chemical reactions. Gain amino groups have solitary pairs of electrons, which can be combined with protons, and can also act as nucleophiles and play a role in many reactions such as nucleophilic substitution reactions. 5 - The chemical structure of Aminoimidazole makes it an important position and application potential in the fields of organic synthesis, medicinal chemistry, etc. In organic synthesis, it is often used as a key intermediate to construct more complex organic molecular structures. In medicinal chemistry, or due to its unique structure and properties, it participates in drug development, providing the possibility for the creation of new drugs.
What are the main uses of 5-Aminoimidazole?
5-Aminoimidazole (5-aminoimidazole) is widely used in the field of organic synthesis and biomedicine.
In organic synthesis, it is a key intermediate and often involves the construction of heterocyclic compounds. Heterocyclic structures are common in many natural products and bioactive molecules. With its unique chemical structure, 5-Aminoimidazole can interact with other reagents through various reaction pathways to construct complex heterocyclic systems with specific functions. For example, it can be condensed with compounds containing carbonyl groups to form novel imidazole heterocyclic rings. This reaction opens up many possibilities for the synthesis of novel organic molecular frameworks.
In the field of biomedicine, 5-Aminoimidazole is also very important. It may be involved in the biosynthesis process of purine nucleotides. Purine nucleotides are raw materials for DNA and RNA synthesis, which are related to key life activities such as cell proliferation and genetic information transmission. 5-Aminoimidazole is involved in it, or has a profound impact on the regulation of cellular physiological functions. In addition, drugs developed on this basis may act on specific biological targets and show therapeutic potential for certain diseases, such as tumors and metabolic disorders. Scientists hope to obtain innovative drugs with high efficiency and low toxicity through structural modification and modification, so as to benefit human health.
Furthermore, 5 - Aminoimidazole is also emerging in emerging fields such as materials science. With the development of science and technology, more unique properties and uses may be discovered, injecting new impetus into the progress of many fields.
What are the physical properties of 5-Aminoimidazole?
5 - Aminoimidazole is an organic compound with unique physical properties. Let me tell you in detail.
The appearance of this compound may be a white to light yellow crystalline powder. Its color is pure and the quality is delicate, just like a natural wonder. Looking at it, it seems to have a shimmering light, just like morning dew shining on the sun, which has a unique charm.
When it comes to melting point, 5 - Aminoimidazole usually shows a phase transition within a certain temperature range, which is of great significance for its identification and purification. Like a precise door, a specific temperature opens, allowing it to sublimate from solid to liquid, showing a different form.
Solubility is also a key property. In water, its degree of solubility may be limited, but it can be better dissolved in some organic solvents, such as alcohols and ethers. Just like a fish entering water, it can stretch freely in a suitable solvent, and the molecules are evenly dispersed, showing the beauty of dissolution.
The density of 5-Aminoimidazole has its own characteristics compared with other similar compounds. Density is like the weight of a substance. Under specific conditions, it reflects its compactness and lays the foundation for its existence and application in different environments.
In addition, its stability cannot be ignored. Under normal temperature and pressure and dry environment, 5-Aminoimidazole is relatively stable, like a quiet place, safe. However, in case of high temperature, humidity or specific chemical reagents, the stability may be affected, and the molecular structure may change, just like the wind and clouds, triggering a series of chemical changes.
In summary, the physical properties of 5-Aminoimidazole, from appearance, melting point, solubility, density to stability, have their own characteristics and are related to each other, forming its unique material characteristics, paving a solid way for its application in many fields such as chemistry and medicine.
What are the synthesis methods of 5-Aminoimidazole?
5 - Aminoimidazole is an organic compound. Its synthesis method has been explored by many scholars in the past, and the number is briefly reported today.
One method is to prepare it by condensation reaction with appropriate nitrogen-containing and carbon-containing substrates. First, the nitrogen-containing reagent meets the carbonyl-containing compound, and under specific conditions, such as suitable solvents, temperatures, and catalysts, the two interact and condensate. In this process, the nitrogen atom and the carbon atom are connected to each other, gradually forming the desired imidazole ring structure, and the amino group is introduced at the appropriate position, and the final result is 5 - Aminoimidazole.
The second method, or modified from a compound with a similar structure. The imidazole derivative with similar structure is taken and chemically modified. For example, the substitution reaction is used to replace the original suitable group with an amino group. In the reaction system, precise reagents are selected and the reaction conditions are regulated, so that the substitution reaction occurs smoothly at the 5 position of the imidazole ring, so as to obtain the target product.
The three methods are also made up of a multi-step reaction strategy. First, the basic skeleton of the imidazole ring is built through several steps of reaction, and then in the subsequent steps, the amino group is introduced into the predetermined position through ingenious reaction design. This multi-step reaction requires detailed control of the conditions of each step, so that each step can achieve the desired result, and the steps cooperate with each other to successfully achieve the synthesis of 5-Aminoimidazole.
All these methods have their own advantages and disadvantages. In actual synthesis, the purpose of synthesis can be achieved only when careful choices are made based on factors such as the availability of raw materials, the difficulty of reaction, and cost considerations.
What are the applications of 5-Aminoimidazole in the field of medicine?
5-Aminoimidazole is widely used in the field of medicine. Gu Yun: "The effect of medicine depends on the symptom." This substance is first involved in the road of anti-tumor in the application of medicine. It can disturb the metabolism of cancer cells and prevent their proliferation. Like the ancient art of war, winning by surprise, 5-aminoimidazole is used in the metabolic path of cancer cells to find its key, cut off its supply, and make the reproduction of cancer cells trapped.
Furthermore, in the context of immune regulation, 5-aminoimidazole can also be used. The immunity of the human body is like the defense of a city. 5-aminoimidazole can help the activity of immune cells and enhance their ability to defend against foreign enemies. Like a brave soldier in the city, with its encouragement, the fighting spirit is high, and it can resist the invasion of germs.
And in terms of nerve protection, 5-aminimidazole has also emerged. The nerves of the brain, like the density of silk threads, are related to people's consciousness. 5-aminimidazole can protect nerve cells and slow their damage, just like the leaves of flowers, so that the energy of nerves can be maintained.
In the field of inflammation regulation, 5-aminimidazole can regulate the production of inflammatory factors. Inflammators, such as the chaos in the city, 5-aminimidazole can calm this chaos and make the body's state peaceful.
To sum up, 5-aminoimidazole is just like a good general in the field of medicine. It is useful in anti-tumor, immune regulation, neuroprotection and inflammation regulation, and contributes to the development of medicine.