5 Aminoimidazole 4 Carboxamide Riboside
quinoline thiophene imidazole thiazole

5-Aminoimidazole-4-carboxamide riboside

    Specifications

    HS Code

    497091

    Chemical Formula C9H15N4O5P
    Molar Mass 290.21 g/mol
    Appearance White to off - white powder
    Solubility In Water Soluble
    Melting Point 170 - 174 °C
    Pka Value ~3.5 (for the ribose - phosphate moiety)
    Cas Number 321-30-2
    Iupac Name [(2R,3R,4S,5R)-5-(4 - amino - 5 - formamido - 1H - imidazol - 1 - yl)-3,4 - dihydroxyoxolan - 2 - yl]methyl dihydrogen phosphate
    Biological Role Intermediate in purine nucleotide biosynthesis, activator of AMP - activated protein kinase
    Stability Stable under normal conditions, but sensitive to strong acids and bases

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    General Information
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    Frequently Asked Questions

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    What is the function of 5-aminoimidazole-4-formamide nucleoside?
    The use of 5-aminopyridine-4-methylpyridyl carbamide hydrazine is particularly important. 5-aminopyridine is often used as a key intermediate in the field of organic synthesis. It can participate in many reactions, such as condensation reactions with compounds such as alaldehyde and ketone, to prepare a variety of nitrogen-containing heterocyclic compounds. These heterocyclic structures are important in pharmaceutical chemistry, materials science and many other aspects.
    And 4-methylpyridyl carbamide hydrazine, in coordination chemistry, can be used as ligands, complexing with metal ions to form rich complexes. These complexes may have specific physical and chemical properties, such as luminescence, catalytic activity, etc. In the process of drug development, these compounds have been modified and modified, or have potential biological activities, such as antibacterial, anti-inflammatory, and anti-tumor effects.
    Combined with the two, 5-aminopyridine-4-methylpyridyl formamide hydrazine may be able to make a name for itself in the creation of new drugs and the development of high-performance materials. With its unique structure, it can introduce different functional groups to build complex molecular systems with specific functions. The practice of organic synthesis can provide chemists with novel strategies and paths to help them explore the unknown chemical space, paving the way for innovation and development in various fields.
    What are the applicable populations of 5-aminoimidazole-4-formamide nucleoside?
    5-Hydroxyquinoline-4-methylpyridone chelating agent can be used for many diseases related to the population, with important medicinal value.
    "Tiangong Kaiwu" cloud: "The use of medicine is related to people's livelihood." 5-Hydroxyquinoline-4-methylpyridone chelating agent has its suitability in various fields of medicine.
    First, it is suitable for people with unbalanced metal ions in the body. For example, lead, mercury and other heavy metal poisoning, this chelating agent can specifically combine with metal ions to form a stable complex, help them excrete from the body, and relieve the danger of poisoning. " The Compendium of Materia Medica also talks about the same principle as "antidote to the poison of gold stone".
    Second, it is beneficial for patients with neurodegenerative diseases. Like patients with Alzheimer's disease, the homeostasis of metal ions in the brain is unbalanced, and the chelating agent can regulate the concentration of metal ions and slow down the progression of the disease. Because abnormal deposition of metal ions can cause neurotoxicity, this chelating agent can prevent their accumulation and protect nerve cells.
    Third, it is also applicable in some inflammatory diseases. Metal ion metabolism changes in the body during inflammation, which can regulate related metal ions and help relieve inflammation.
    Fourth, it is used in scientific research related to cell culture. When studying the effect of specific metal ions on cells, this chelating agent can be added to adjust the concentration of metal ions in the environment, accurately simulate physiological and pathological conditions, and explore the way for medical research.
    When used, when following the doctor's instructions, because of its complicated effect, improper dosage or other changes. Doctors should understand the pharmacology, observe the condition, and use it cautiously, so that this good medicine can exert its effect and protect the common people.
    What are the side effects of 5-aminoimidazole-4-formamide nucleoside?
    5-Hydroxytryptamine and 4-acetylmuramate hydrazine are both important biochemical substances, and each has many wonderful side effects on the body.
    5-Hydroxytryptamine, also known as serotonin, is widely distributed in the body. In moderation, it can regulate mood, promote sleep, and control appetite. However, its levels are unbalanced, resulting in many drawbacks. If the content is too low, people are prone to depression and anxiety, often accompanied by insomnia and loss of appetite. Because 5-Hydroxytryptamine acts as a neurotransmitter in the nervous system, transmits nerve signals, and has a significant impact on physiological activities such as mood and sleep. When the content is insufficient, nerve signal transmission is blocked, mood regulation is abnormal, and sleep rhythm is also disrupted.
    4-Acetylmurate hydrazine, mainly exists in the synthesis process of bacterial cell wall. In the field of antibacterial drug action mechanism, if the drug interferes with the synthesis process of 4-Acetylmurate hydrazine, although it can inhibit the growth of bacteria, it may cause abnormal immune responses in the body. Due to changes in bacterial cell wall components, or misjudgment by the immune system, its normal cells are also targeted, triggering immune side reactions similar to allergies. In addition, long-term use of drugs that interfere with such synthesis may cause bacterial resistance. In order to survive, bacteria will change their own metabolic pathway, making the drug unable to act on the target of hydrazine 4-acetyl murinate synthesis, and gradually develop drug resistance, making antibacterial treatment more difficult.
    What is the use of 5-aminoimidazole-4-formamide nucleoside?
    In the "Heavenly Works", 5-methyltryptamine has not been used, and it has not been involved in this matter. As for the use of 4-methylimidazoprine, the ancients did not use this thing, so it is also mentioned in this article.
    The "Heavenly Works" is the work of a hundred industrial techniques, which was completed in the Ming Dynasty for ten years. The general works described, such as mulberry, smelting, Zhoujian, pottery, etc., are all based on the usual materials and techniques. The 5-methyltryptamine and 4-methylimidazoprine are the materials obtained by the research of modernization, and their properties and uses are not known to the ancients.
    5-methyltryptamine, also known as serotonin, is very important for human physiology, such as emotion, sleep, and food. 4-Methylimidazoprine, or the process of biological chemistry, is related to cell generation, gene table, etc. However, both of these are the results of chemical and biological research, which are beyond the reach of "Tiangong". Therefore, it is impossible to obtain it if you want to use it in "Tiangong".
    5-Aminoimidazole-4-formamide nucleoside is used in the treatment of which diseases
    5-Aminosalicylic acid and 4-methylpyriformamidoquinoline are used in the treatment of many diseases.
    5-Aminosalicylic acid is mostly used for intestinal diseases, such as ulcerative colitis. This drug can play a local role in the intestines, inhibit the generation and release of inflammatory mediators, reduce the inflammatory response of intestinal mucosa, relieve abdominal pain, diarrhea, mucus, pus and blood stool. When the first or recurrence of ulcerative colitis such as mild to moderate, it is often used as the main drug for treatment to help the intestines restore peace.
    4-methylpyriformamidoquinoline is quite useful in the field of antibacterial and anti-inflammatory. It has the ability to inhibit a variety of bacteria, can interfere with the metabolic process of bacteria, destroy the cell wall and cell membrane of bacteria, and then inhibit the growth and reproduction of bacteria. In some infectious diseases, such as respiratory tract infections, skin and soft tissue infections, etc., if the pathogenic bacteria are sensitive to them, they can be used to fight evil energy and restore righteousness.
    The application of the two is designed to heal diseases and protect human health. 5-Aminosalicylic acid focuses on the conditioning of intestinal inflammation, and 4-methylpyridine-formamidoquinoline focuses on the fight against bacterial infections. Doctors should accurately distinguish and choose the drug according to the specific condition and symptoms of the patient, so as to maximize the efficacy and help the patient get out of the disease as soon as possible and return to health.