5 Aminobenzimidazole
quinoline thiophene imidazole thiazole

5-Aminobenzimidazole

    Specifications

    HS Code

    643139

    Chemical Formula C7H7N3
    Molecular Weight 133.15 g/mol
    Appearance Solid
    Melting Point 174 - 176 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol
    Odor Odorless
    Color White to off - white
    Stability Stable under normal conditions

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    General Information
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    Frequently Asked Questions

    As a leading 5-Aminobenzimidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-aminobenzimidazole?
    What are the main uses of 5-aminoquinoline and oxazoline?
    5-aminoquinoline has many applications in the field of medicine. It can be used as a key intermediate for the synthesis of antimalarial drugs. The prevention and treatment of malaria is an important part. Because of the development and proliferation process of Plasmodium in human red blood cells, 5-aminoquinoline compounds can interfere with its metabolic pathway, achieve the effect of killing Plasmodium, and thus cure malaria patients. And in the development of antimicrobial drugs, it may also be useful, interacting with bacterial targets in vivo through specific structures to inhibit bacterial growth and reproduction.
    oxazoline compounds have significant effects in the field of polymer materials. First, it can be used as a monomer for polymerization reaction, and the polymer with specific properties can be obtained by polymerization reaction. Such polymers may have good thermal stability and mechanical properties, and can be used in industries that require strict material properties such as aerospace and automobile manufacturing to manufacture specific parts. Second, oxazoline can be used as an auxiliary agent and added to polymer materials to improve the processing properties of materials, such as enhancing material fluidity, making the molding process smoother; or improving material aging resistance and prolonging material service life.
    In the field of organic synthesis, oxazoline is often used as an intermediate. Through a series of chemical reactions, it is converted into organic compounds with more complex structures and more diverse functions, providing rich raw materials and possibilities for the development of organic synthesis chemistry.
    What are the synthesis methods of 5-aminobenzimidazole?
    5-Aminoquinoline-pyridine compounds have attracted much attention in the field of organic synthesis chemistry today. The synthesis methods are many ingenious, and this is the way for you.
    First, based on quinoline and pyridine derivatives, the purpose can be achieved through condensation reaction. For example, select suitable halogenated quinoline and pyridylamine, and place them in an organic solvent under the catalysis of a base, heat and stir. In this process, the base can help the halogen of halogenated quinoline to leave, and the amino nucleophilic attack of pyridylamine will form a carbon-nitrogen bond, and then obtain the prototype of 5-aminoquinoline-pyridine. The key to the reaction lies in the structural selection of halogenated quinoline and pyridylamine, which must be adapted to the reaction conditions, and the type and dosage of bases, the polarity of the solvent, etc., are all related to the yield and selectivity of the reaction.
    Second, through cyclization reaction. Starting with a chain precursor containing an appropriate functional group, the functional group is first converted to introduce a cyclized activity check point. For example, compounds with alkenyl groups and amino groups can initiate intramolecular cyclization under the catalysis of transition metals. Transition metal catalysts can activate alkenyl groups, make amino groups and them addition cyclize, and construct a fused ring structure of quinolinopyridine. During this period, the type of metal catalyst and the design of ligands are very important, which can regulate the activity and selectivity of the reaction, and can also affect the stereochemistry of the product.
    Third, the multi-component reaction is used. Several simple raw materials, such as aldose, amine, alkyne, etc., are placed in the same reaction system. Aldose and amine are first condensed into imines, and imines are then cyclized and added to alkynes to form a complex structure of 5-aminoquinoline-pyridine in one step. The advantages of this method are that it is easy to operate, has high atomic economy, and can efficiently synthesize target products with diverse structures. However, the precise control of reaction conditions is essential, and factors such as the proportion of raw materials, reaction temperature, and time all affect the purity and yield of the product.
    This number method has its own advantages and disadvantages. In actual synthesis, when carefully considering the structural characteristics of the target product, the availability of raw materials, the cost and efficiency of the reaction, etc., the optimal method is selected to form 5-aminoquinolinopyridine compounds.
    What fields are 5-aminobenzimidazole used in?
    5-Hydroxytryptamine and oxytocin are used in many fields.
    In the field of medicine, 5-Hydroxytryptamine is closely related to physiological processes such as mood, sleep, and appetite. If its levels are unbalanced, it is easy to cause depression, anxiety and other psychiatric diseases. Therefore, many antidepressants are designed to regulate 5-Hydroxytryptamine levels and help patients relieve symptoms. Oxytocin is widely used in obstetrics and gynecology, which can stimulate uterine contraction, help childbirth, and reduce the risk of postpartum bleeding to ensure maternal safety.
    In the field of psychology, 5-Hydroxytryptamine can affect individual mood and cognition. Studies have shown that those with higher levels tend to have more positive emotions and better cognitive function. Oxytocin is associated with social behaviors such as trust and empathy, which can enhance interpersonal trust and intimacy, and may have potential roles in psychotherapy and interpersonal relationship regulation.
    In the field of neuroscience, these two are of great significance for the development and function maintenance of the nervous system. 5-Hydroxytryptamine participates in neurotransmitter transmission and regulates nerve cell activity; oxytocin also plays a role in the development of the nervous system, affecting the formation and plasticity of neural circuits.
    Furthermore, at the level of animal behavior, 5-Hydroxytryptamine and oxytocin affect animals' social and reproductive behaviors. Many animal studies have shown that oxytocin can promote parental rearing behavior and enhance the connection between mother and baby; 5-hydroxytryptamine is associated with animal aggression, exploration and other behaviors.
    In summary, 5-hydroxytryptamine and oxytocin play key roles in many fields such as medicine, psychology, neuroscience and animal behavior, and have a profound impact on life activities and human social behavior.
    What is the market prospect of 5-Aminobenzimidazole?
    5-Hydroxyindolopyridine is an emerging compound that shows unique application potential in many fields such as medicine and materials. Its market prospects are as follows:
    ###Pharmaceutical field
    1. ** Anti-cancer drug research and development **: At present, cancer is still a major disease that seriously threatens human health, and the demand for anti-cancer drugs continues to grow. Studies have shown that the structure of 5-hydroxyindolopyridine may have the characteristics of inhibiting cancer cell proliferation and inducing cancer cell apoptosis. Over time, if new anti-cancer drugs with this as the core ingredient can be successfully developed, the market size will be extremely impressive. The global anti-cancer drug market size is increasing year by year. For example, in the US market alone, annual anti-cancer drug sales can reach tens of billions of dollars. If 5-hydroxyindolopyridine-related anticancer drugs can account for a certain share, its commercial value should not be underestimated.
    2. ** Treatment of neurological diseases **: The number of patients with neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease is increasing. 5-hydroxyindolopyridine may provide a new path for the treatment of neurological diseases by modulating neurotransmitters and inhibiting neuroinflammation. With the increasing aging of the population, the market for neurological diseases will also expand steadily, and this compound is expected to get a share of it.
    ##Materials
    1. ** Organic Light Emitting Materials **: In the field of display technology, organic Light Emitting Diode (OLED) is developing rapidly. 5-Hydroxyindolopyridine may be used as an OLED light-emitting layer material to improve the luminous efficiency and color saturation of display devices due to its unique optical properties. As OLED continues to increase in the market share of mobile phones, televisions and other display screens, the demand for new organic light-emitting materials is also rising. Once 5-Hydroxyindolopyridine is applied in this field, it will face a broad market space.
    2. ** Sensor Materials **: With its ability to selectively identify and respond to specific substances, 5-Hydroxyindolopyridine may be used to develop new sensors, such as the detection of environmental pollutants, biomarkers, etc. As people pay more attention to environmental monitoring and health diagnostics, the scale of the sensor market continues to expand, and 5-hydroxyindolopyridine may have opportunities to emerge in this field.
    ###Development challenges and opportunities coexist
    Although the market prospect of 5-hydroxyindolopyridine seems bright, it also faces many challenges. On the one hand, its synthesis process may still need to be optimized to improve yield, reduce costs, and enhance market competitiveness; on the other hand, a lot of in-depth research is needed to clarify its specific mechanism and safety in various fields. However, opportunities cannot be ignored. With technological progress and in-depth research, if the above problems can be overcome, 5-hydroxyindolopyridine will surely shine in many fields and open up a new market pattern.
    What are the physical and chemical properties of 5-aminobenzimidazole?
    5-hydroxyquinolinopyridine is an organic compound with unique physical and chemical properties.
    In terms of physical properties, 5-hydroxyquinolinopyridine is usually in a solid form and is quite stable at room temperature and pressure. Its melting point and boiling point depend on intermolecular forces and structural properties. Because the molecule contains a conjugated system, it can exhibit absorption and emission characteristics under specific wavelengths of light, or has fluorescence properties, which has potential applications in the field of fluorescence analysis and optical materials.
    From the perspective of chemical properties, the hydroxyl groups and nitrogen heterocycles in the molecule of 5-hydroxyquinolinopyridine give it reactivity. Hydroxyl groups can participate in reactions such as esterification and etherification, and can react with acid anhydrides, acyl halides, etc., to form corresponding ester derivatives, which provides the possibility for the synthesis of complex organic compounds. The nitrogen atom in the nitrogen heterocycle can act as a ligand to coordinate with metal ions to form metal complexes, which are widely used in catalysis, materials science and biomedical fields. For example, metal complexes may exhibit unique optical, electrical and magnetic properties, or have high activity and selectivity in catalytic reactions. In addition, the conjugated structure of the compound enables it to undergo electrophilic substitution reactions, and substituents can be introduced at specific positions in the aromatic ring, thereby modifying and optimizing molecular properties to meet the needs of different fields. With its unique physical and chemical properties, 5-hydroxyquinolinopyridine has broad application prospects in materials science, chemical synthesis, biomedicine and other fields, providing many opportunities for scientific research and industrial production.