5 Amino 4 Imidazole Carboxamide Hcl
quinoline thiophene imidazole thiazole

5-Amino-4-Imidazole carboxamide HCL

    Specifications

    HS Code

    141431

    Chemical Formula C4H6N4O·HCl
    Molar Mass 174.58 g/mol
    Appearance White to off - white powder
    Solubility In Water Soluble
    Melting Point Approximately 169 - 172 °C
    Ph Of Solution Acidic (in aqueous solution)
    Odor Odorless
    Stability Stable under normal conditions
    Storage Conditions Store in a cool, dry place
    Cas Number 61-82-5

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    General Information
    Where to Buy 5-Amino-4-Imidazole carboxamide HCL in China?
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    Frequently Asked Questions

    As a leading 5-Amino-4-Imidazole carboxamide HCL supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 5-amino-4-imidazole formamide hydrochloride?
    5-Hydroxy-4-methoxyacetophenone benzoyl oxybenzoic anhydride is mainly used in a lot. This is a key intermediate in organic synthesis and has important uses in many fields.
    In the field of pharmaceutical chemistry, it can be used as a starting material for the synthesis of specific drugs. Due to the hydroxyl and methoxy functional groups contained in the molecular structure, it is endowed with unique chemical activities and pharmacological properties. Through a series of organic reactions, it can ingeniously construct drug molecular structures with specific physiological activities, which is of great significance for the development of drugs for the treatment of diseases such as cardiovascular diseases and nervous system diseases.
    In the field of materials science, it also has a place. It can be introduced into the structure of polymer materials by polymerization reaction or modification reaction. With its special chemical structure, it can improve the optical and electrical properties of polymer materials, such as enhancing the fluorescent properties of materials, or enhancing their conductivity, and then widely used in the preparation of optoelectronic devices, sensors and other materials.
    In the field of fragrance industry, because it has a specific aromatic smell, it can become an important part of fragrance after proper preparation and processing. It imparts a unique aroma to perfumes, flavors and other products, and enhances the quality and market competitiveness of products.
    In addition, in the field of fine chemicals, it can be used to synthesize various fine chemicals, such as special dyes, additives, etc. Through the modification and modification of its structure, fine chemicals that meet different needs can be prepared to meet the diverse needs of industrial production and daily life. From this point of view, 5-hydroxy-4-methoxyacetophenone benzooxybenzoic anhydride plays an indispensable role in many fields and contributes greatly to the promotion of technological development and product innovation in various fields.
    What are the physical properties of 5-amino-4-imidazole formamide hydrochloride?
    The physical properties of 5-amino-4-cyanobenzoate ethyl anhydride are as follows:
    This substance is often in the state of white to off-white crystalline powder. Looking at its appearance, the texture is uniform, the color is pure, and there is no obvious variegation and foreign matter.
    Its melting point is quite critical, and it is about a specific temperature range. This melting point characteristic is one of the important markers for the identification of this substance. Due to the relatively fixed melting point, at the corresponding temperature, the substance will gradually change from solid to liquid. The accuracy of this temperature range is of great significance for the determination of its purity.
    In terms of solubility, it shows specific solubility characteristics in common organic solvents. In organic solvents such as ethanol and acetone, there is a certain solubility. In ethanol, with the increase of temperature, the solubility increases, and a uniform solution system can be formed; in acetone, the dissolution rate is relatively fast, and it can be uniformly dispersed in a short time to form a clear solution. However, in water, its solubility is very small. Due to the large difference between the molecular structure of the substance and the polarity of water, it is difficult for the two to blend.
    Density is also one of its important physical properties. After determination, its density has a specific value. This property is not only related to the relationship between the weight and volume of the substance itself, but also has important reference value in many practical application scenarios, such as the ratio of materials in chemical production, storage and transportation space planning, etc.
    In addition, the stability of the substance cannot be ignored. Under normal temperature and humidity conditions, the properties are relatively stable, and chemical reactions such as decomposition and oxidation are not easy to occur. However, under extreme conditions such as high temperature, high humidity or strong acid and alkali, its chemical structure may be damaged, which in turn affects its physical properties and chemical activities.
    The many physical properties of this 5-amino-4-cyanobenzoate ethyl anhydride provide an important foundation for its application in chemical, pharmaceutical and other fields.
    Is 5-Amino-4-imidazolecarbamide hydrochloride chemically stable?
    5-Amino-4-chlorobenzoic acid ethyl ester amide anhydride, its chemical properties are relatively unstable.
    This compound contains various functional groups such as amino groups, chlorine atoms, ester groups, amide groups and acid anhydrides. The part of the acid anhydride is easily hydrolyzed in contact with water to form the corresponding carboxylic acid. The hydrolysis reaction is due to the nucleophilic nature of the oxygen atom in the water molecule, which attacks the carbonyl carbon of the acid anhydride, causing the acid anhydride bond to break and forming carboxylic acids. This hydrolysis process usually occurs under mild conditions, such as in humid air or in an aqueous environment, the acid anhydride part is gradually hydrolyzed.
    The ester group also has certain activity, and the hydrolysis reaction can occur under the catalysis of acid or base. Under acidic conditions, the carbonyl group of the ester group is protonated in advance, which enhances the positive electricity of the carbonyl carbon, which is conducive to the attack of water molecules. After a series of reactions, carboxylic acids and alcohols are formed; under alkaline conditions, the hydroxide ion nucleophilic attacks the carbonyl carbon, and the reaction is more rapid, forming carboxylic salts and alcohols.
    Furthermore, the amino group has a certain alkalinity and can react with acids to form salt compounds. Although the chlorine atom is relatively stable, under certain conditions, such as high temperature, strong base or when there is a suitable catalyst, a substitution reaction can occur and be replaced by other nucleophilic reagents.
    In summary, 5-amino-4-chlorobenzoic acid ethyl ester amide anhydride contains a variety of active functional groups, and its chemical properties are unstable. It is prone to various chemical reactions in different environments, resulting in changes in its structure and properties.
    What are the synthesis methods of 5-amino-4-imidazole formamide hydrochloride?
    The synthesis of 5-amino-4-cyanobenzoic acid ethyl ester amide anhydride covers many ways. The ancient Fang family has explored this method in depth, and the following are common methods:
    First, benzoic acid derivatives are used as the starting point. First, benzoic acid is taken, and a halogen atom is introduced at a specific position through halogenation. This halogen atom is highly active and can be used as the basis for subsequent reactions. Then, a cyanide reagent is used to react with it to introduce a cyanide group. This process requires fine regulation of the reaction conditions, such as temperature, pH, etc., so that the cyanide group can be accurately integrated. Then treated with an amination reagent to obtain 5-amino-4-cyanobenzoic acid. Finally, it is co-reacted with ethanol and a dehydrating agent to form an ester state. After amidation, cyclization and dehydration, etc., the target acid anhydride is obtained. Although there are many steps in this path, each step can be controlled. If the operation is skilled, a higher yield can be obtained.
    Second, benzonitrile is used as the starting material. Benzonitrile is first introduced into the carboxyl group precursor at an appropriate position through a specific electrophilic substitution reaction, and then hydrolyzed to obtain a carboxyl-containing benzonitrile derivative. Then an amination reaction is carried out, an amino group is added, and an esterification method is used to react with ethanol to form an ester. Subsequently, an appropriate amidation agent is used to form an amide state, and finally, under the action of a dehydrating agent, cyclization dehydrates to This approach starts with benzonitrile, and the raw materials are easy to obtain. However, the selectivity of each step of the reaction should be paid attention to in the reaction to avoid the growth of side reactions.
    Third, there are those obtained by ring-opening reaction of specific heterocyclic compounds. Select the appropriate heterocyclic ring, which needs to contain potential carboxyl groups, cyano groups, amino groups and ester groups. After specific ring-opening reagents and reaction conditions, it is opened and gradually converted to form the groups required by the target molecule in turn, and finally cyclized and dehydrated to form 5-amino-4-cyanobenzoic acid ethyl ester amide anhydride. Although this method is relatively new, it is extremely demanding for the selection of heterocyclic raw materials and the control of reaction conditions.
    What is the price range of 5-amino-4-imidazolecarbonamide hydrochloride in the market?
    The price of 5-hydroxy-4-methoxyacetophenone anhydride in the market varies with time, place and quality. In today's market, this product is often used in the pharmaceutical and chemical industries, and its price range, roughly speaking, may range from tens to hundreds of dollars per gram.
    If it is of high quality, and the preparation method is exquisite, and it is popular in the market, the price may increase, reaching hundreds of dollars per gram. However, if the quality is average, and the market supply is sufficient and the demand is small, the price may drop to tens of dollars per gram.
    Furthermore, the amount purchased is also related to the price. If a large quantity is purchased, the merchant may give a discount in order to promote the sale, and the price per gram may be slightly reduced.
    The movement of its price is like a wave of water, which changes with the supply and demand of the market, the quality of quality, and the change of time. To know its exact price, when you carefully observe the current situation of the market and consult all merchants, you can obtain a more accurate number.