5-amino-1h-imidazole-4-carboxamid

5-Amino-1H-imidazole-4-carboxamide, i.e. 5-amino-1H-imidazole-4-formamide, has the chemical formula\ (C_ {4} H_ {6} N_ {4} O\), and the chemical structure is as follows.
This compound consists of an imidazole ring forming the core structure. The imidazole ring is a five-membered heterocycle containing two nitrogen atoms, which are connected to the hydrogen atom at position 1, which is the structural basis of 1H-imidazole. A formamide group (\ (- CONH_ {2}\)) is connected to the 4 position of the imidazole ring. In the formamide group, the carbon atom is connected to the oxygen atom by a double bond, and the nitrogen atom is connected by a single bond. Two hydrogen atoms are also connected to the nitrogen atom. In the 5 position of the imidazole ring, an amino group (\ (- NH_ {2}\)) is connected, and the amino group is composed of a nitrogen atom and two hydrogen atoms. In this way, each atom is connected by a covalent bond to form a chemical structure of 5-amino-1H-imidazole-4-formamide.

5-Amino-1H-imidazole-4-carboxamide, that is, 5-amino-1H-imidazole-4-formamide, has a wide range of main uses.
In the field of medicine, this is an important pharmaceutical intermediate. It is used as the starting material for the synthesis of many drugs, and through a series of chemical reactions, drugs with specific pharmacological activities can be prepared. For example, in the development of some anti-tumor drugs, 5-amino-1H-imidazole-4-formamide plays a key role in its synthesis pathway, which plays a role in the growth and proliferation of tumor cells, and then provides an effective means for the treatment of cancer.
In the field of biochemical research, it is an important tool to explore the metabolic process of cells. Many metabolic pathways in cells are related to it, and scientists can gain insight into the mechanism of cell metabolism by studying the metabolic reactions they participate in. For example, in the biosynthetic pathway of purine nucleotides, 5-amino-1H-imidazole-4-formamide participates in the key steps. By studying this process, it is possible to better understand how cells synthesize the basic components of genetic material, which is of great significance to basic research in life sciences.
In the field of agriculture, there are also some potential uses. The development of some new pesticides or plant growth regulators may use 5-amino-1H-imidazole-4-formamide as the basic raw material. It may promote plant growth and enhance plant resistance to diseases and pests by regulating the physiological and biochemical processes in plants, thereby assisting agricultural production and improving crop yield and quality.

5-Amino-1H-imidazole-4-carboxamide (5-amino-1H-imidazole-4-formamide), this material property is special, related to chemistry. Its color state is also, at room temperature, or white powder, fine and uniform, looking like frost and snow, it has a greasy feeling to the touch. Its taste, or slightly specific, but not pungent, strong taste, only when you smell it, you feel a little different smell.
In terms of its solubility, it has a certain degree of solubility in water, just like ice crystals entering water, gradually melting into the invisible. Water is the source of life, and this substance is in contact with water. It can also be seen that the polar groups contained in its molecular structure interact with water molecules, so they are soluble. However, in organic solvents, such as ethanol and ether, their solubility varies. For ethanol, it is warm and well-soluble, and 5-amino-1H-imidazole-4-carboxamide is in it, and the solubility is higher than that of ether. For ether, it has strong volatility, and its intermolecular force interacts weakly with 5-amino-1H-imidazole-4-carboxamide, so the solubility is slightly inferior.
As for its melting point, which is an inherent characteristic of the substance, the melting point of 5 - amino - 1H - imidazole - 4 - carboxamide is also fixed. When the temperature gradually rises and reaches its melting point, the solid phase will gradually change the liquid phase, such as ice and snow melting, morphological changes. The value of this melting point can be the key to identifying this substance, and it is also of great significance in its purification and refining process.
Looking at its stability, it can be stable for a long time at room temperature and pressure, protected from light and moisture. However, in case of strong acid and alkali, or extreme conditions of high temperature and hot topic, its molecular structure is easily damaged, chemical reactions occur, and other substances are formed. This is like jade placed in a fire, although it is firm and melted. When storing and using, when avoiding such adverse conditions, its properties can be maintained.

The synthesis of 5-amino-1H-imidazole-4-formamide is an important topic in the field of organic synthesis. In the past, many experts have studied this method and followed the classical organic synthesis path.
One method can be started from a suitable imidazole derivative. First, imidazole with a specific substituent is used as a substrate, and an amino group is introduced under suitable reaction conditions. This step often requires the use of nucleophilic substitution reactions to select moderately active amination reagents, such as certain amine compounds, to react with imidazole substrates when the catalyst exists. The choice of catalyst is very important, either metal salts or organic bases, which can promote the reaction, improve the reaction rate and yield.
Second, the formamide group is introduced at the 4-position of the imidazole ring. This process can be used for acylation reaction, taking formylation reagents, such as formamide derivatives, and reacting with aminylated imidazole derivatives. The reaction environment needs to be carefully controlled, and factors such as temperature and solvent are all related to the success or failure of the reaction. The choice of solvent should be good for solubility of the reactants and does not interfere with the reaction process, such as some polar organic solvents.
There is another way to start with the construction of imidazole rings. The imidazole ring structure was constructed by multi-step reaction with nitrogen-containing and carbon-containing small molecule compounds as raw materials, and amino groups and formamide groups were introduced at appropriate positions on the ring. This approach requires precise design of reaction steps and orderly introduction of functional groups to achieve the synthesis of the target product. Each step requires careful consideration of reaction conditions to ensure the selectivity and efficiency of the reaction, so that 5-amino-1H-imidazole-4-formamide can be obtained.

5-Amino-1H-imidazole-4-carboxamide (5-amino-1H-imidazole-4-formamide), the price range in the market is difficult to determine. The price often changes due to various reasons, such as the abundance of materials, the simplicity of the craftsmanship, and the state of demand.
Looking at the city of the past, if the materials are sufficient, the craftsmanship is not very complicated, and there are not many applicants, the price may be slightly cheaper. However, if the materials are scarce, the craftsmanship is difficult, and there are many applicants, the price will be high.
According to normal conditions, its price per gram may be between tens of gold and hundreds of gold. If it is a high-purity product, and the preparation method is extremely exquisite, and it is widely sought in the market, its price may exceed hundreds of gold per gram. On the contrary, if the purity is slightly inferior, the preparation method is ordinary, and the supply is oversupplied, the price per gram may be tens of gold ears. However, this is a rough estimate, and the market situation changes, and it is difficult to be sure.