5 Amino 1 Beta D Ribofuranosyl 1h Imidazole 4 Carboxamide
quinoline thiophene imidazole thiazole

5-amino-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide

    Specifications

    HS Code

    970572

    Chemical Formula C9H13N5O4
    Molar Mass 255.23 g/mol
    Appearance White to off - white powder
    Solubility In Water Soluble
    Pka Around 8.4
    Melting Point 179 - 182 °C
    Stability Stable under normal conditions
    Odor Odorless

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    General Information
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    Frequently Asked Questions

    As a leading 5-amino-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 5 - amino - 1 - (beta - D - ribofuranosyl) -1H - imidazole - 4 - carboxamide
    5-Amino-1 - (β - D-ribosyl) -1H-imidazole-4-formamide, which is an organic compound. Among its chemical structures, the core is the imidazole ring, which is quite common in many bioactive molecules.
    Looking at its structure, the 1-carbon of the imidazole ring is connected to the β-D-furan ribosyl group by glycosidic bonds. The β-D-furan ribosyl group is a carbohydrate structure with five carbon atoms, in the state of a furan ring, and its three-dimensional configuration is β-type, which has a profound impact on the recognition and reaction of the compound in vivo.
    Furthermore, the 4-position carbon of the imidazole ring is connected to the carboxyamide group. This functional group is rich in heteroatoms such as nitrogen and oxygen, and can interact with biological macromolecules through hydrogen bonding. The 5-position carbon is connected with an amino group, which is nucleophilic and can participate in many chemical reactions. It plays a key role in biosynthesis, metabolism and other processes.
    The structural characteristics of this compound endow it with unique physical, chemical and biological properties, which have attracted much attention in the fields of medicine, biochemistry, etc. It may be used as a lead compound for drug development, or play a key role in biological metabolism research.
    What are the medical applications of 5 - amino - 1 - (beta - D - ribofuranosyl) -1H - imidazole - 4 - carboxamide
    5-Amino-1 -(β - D-nitrofuran) -1H-imidazole-4-formamide is widely used in medical medicine.
    This substance plays a key role in the synthesis of nucleotides. It is an important intermediate for de novo synthesis of purine nucleotides, which helps greatly in the process of cell proliferation and differentiation. When cells grow and multiply, a large number of nucleotides are required to form nucleic acids. The presence of 5-amino-1 -(β - D-furan) -1H-imidazole-4-formamide can ensure the smooth synthesis of purine nucleotides and maintain the normal physiological function of cells.
    In the field of pharmaceutical research and development, it is also valued. Based on this, many drugs can be prepared. For example, the design of some anti-cancer drugs is based on its characteristics. Tumor cells proliferate rapidly and have a huge demand for nucleotides. In response to this, drugs developed based on the relevant mechanism of this substance can interfere with tumor cell nucleotide synthesis, inhibit its growth, and achieve anti-cancer effects.
    In addition, it also has manifestations in immune regulation. It can affect the metabolism and function of immune cells, or provide new avenues for the treatment of immune-related diseases. Such as autoimmune diseases, or it can use its regulation of immune cell nucleotide synthesis to correct abnormal functions of immune cells and improve the condition.
    In addition, it also has potential in the field of nutritional supplementation. It can provide the body with raw materials for nucleotide synthesis and help maintain normal physiological metabolism. Especially for people who are weak, postoperative or have low immunity, or can use supplements containing this substance to promote physical recovery and increase immunity.
    What is the production and preparation method of 5 - amino - 1- (beta - D - ribofuranosyl) -1H - imidazole - 4 - carboxamide
    5-Amino-1 - (β - D-ribosyl furanoyl) -1H-imidazole-4-formamide, the preparation method of this substance is as follows:
    First take an appropriate amount of β-D-furan ribose, place it in the reactor, add a specific proportion of protective reagents in a mild state to protect the specific hydroxyl groups on the ribose. This step is designed to create suitable conditions for subsequent reactions and prevent unnecessary side reactions. < Br >
    Then, the reactant containing amino and imidazole structures is introduced, and the condensation reaction with the protected ribose is promoted under the environment of precisely controlled temperature and pH. During the reaction, the reaction process is closely monitored, and the degree of reaction can be checked by thin-layer chromatography or other suitable analytical methods.
    When the condensation reaction achieves the desired effect, the previously introduced protective group is removed by a gentle method. This process requires strict control of the reaction conditions to avoid damage to the formed key structure.
    Next, the reaction product is separated and purified. The product can be extracted with an organic solvent first to enrich in the organic phase and remove most of the impurities. Subsequently, column chromatography was used to carefully select suitable stationary and mobile phases, and the product was further purified to obtain high-purity 5-amino-1 - (β - D-furan ribosyl) -1H-imidazole-4-formamide.
    The whole preparation process is very critical to the control of the reaction conditions, the sequence of each step and the proportion of the reactants. A little poor pool may cause the product to be impure or the yield to be low.
    What are the physicochemical properties of 5 - amino - 1- (beta - D - ribofuranosyl) -1H - imidazole - 4 - carboxamide
    5-Amino-1 - (β - D-nitrofuran) -1H-imidazole-4-formamide, this is an organic compound. It has a number of physical and chemical properties.
    Looking at its properties, it mostly shows the appearance of white crystalline powder under normal conditions, which is easy to identify and operate. As for solubility, it has a certain solubility in water, but in organic solvents, such as ethanol, ether, etc., the solubility is different. It is slightly soluble in ethanol or slightly soluble in ether, but poor solubility in ether. This property is related to its application and separation in different solvent systems.
    When it comes to melting point, it has been experimentally determined that the melting point of the substance is quite clear, and it is located in a certain temperature range. This temperature limit is an important physical identification of the compound, which is of great value in identification and purity judgment. Its stability is also an important property, and it can maintain a relatively stable state in a dry environment at room temperature; however, in case of high temperature, high humidity or specific chemical reagents, its structure may change, causing chemical properties to change.
    Furthermore, the compound contains specific functional groups, such as amino groups, amide groups, etc. These functional groups give it unique chemical activity. Amino groups have certain alkalinity and can react with acids to form corresponding salts; amide groups can participate in reactions such as hydrolysis under specific conditions. These reaction properties lay the foundation for their application in organic synthesis, medicinal chemistry, etc., and the desired derivatives can be prepared by rationally designing the reaction to expand their uses.
    5 - amino - 1 - (beta - D - ribofuranosyl) -1H - imidazole - 4 - carboxamide
    5-Amino-1 - (β - D-nitrofuran) -1H-imidazole-4-formamide, which has a good prospect in the field of pharmaceutical and chemical industry.
    It has significant effect on the medical end. At the level of immune regulation, it can stimulate the human immune system, greatly increase the vitality of immune cells, and has extraordinary effect on resisting external evil and maintaining the health of the body. In the field of tumor treatment, it has also emerged, which may inhibit the proliferation of tumor cells and induce their apoptosis. It is a powerful way to fight cancer, and compared with traditional therapies, the side effects may be smaller, bringing new hope to many patients.
    In the chemical industry, this substance is an important synthetic raw material. Based on it, a variety of high-value-added fine chemicals can be prepared, such as materials with special functions, new catalysts, etc. These downstream products are widely used in cutting-edge fields such as electronics and materials science, which greatly promotes the progress of related industries.
    From the perspective of market supply and demand, with the deepening of pharmaceutical research and development and the expansion of the chemical industry, the demand for it is on the rise. Pharmaceutical companies are increasingly demanding better drugs for research and development, and chemical companies are producing new materials. However, there is still room for improvement in their production processes, and some links are technically difficult and costly. This is the bottleneck that restricts their large-scale supply.
    Although it faces cost and technical challenges, it has great potential in the field of medicine and chemical industry. With the advancement of science and technology, if we can overcome production problems, optimize processes, and reduce costs, we will be able to shine in the market and create brilliant achievements for human health and industrial development.