5 6 Dichloro 1h Benzimidazole
quinoline thiophene imidazole thiazole

5,6-Dichloro-1H-benzimidazole

    Specifications

    HS Code

    609171

    Chemical Formula C7H4Cl2N2
    Molecular Weight 187.026 g/mol
    Appearance Solid
    Melting Point 240 - 242 °C
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents
    Stability Stable under normal conditions
    Hazardous Nature May be harmful if swallowed, inhaled or in contact with skin

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    General Information
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    Frequently Asked Questions

    As a leading 5,6-Dichloro-1H-benzimidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 5,6-dichloro-1H-benzimidazole?
    5,6-Dioxide-1H-indoleo-indolequinone is an important class of organic compounds with critical uses in many fields.
    In the field of medicine, it exhibits significant biological activity. Many studies have revealed that these compounds have inhibitory effects on the growth of tumor cells, or can play an anti-cancer role by affecting cell cycle regulation and inducing apoptosis. Some 5,6-dioxide-1H-indoleo-indolequinone derivatives have been experimentally verified to selectively act on specific tumor cell lines and have relatively low toxicity to normal cells, providing an important direction for the development of new anti-cancer drugs. At the same time, it also has potential value in the treatment of neurological diseases, or can regulate the release and metabolism of neurotransmitters, providing new ideas for the treatment of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
    In the field of materials science, 5,6-dioxy-1H-indole-indolquinone can be used as a building block for functional materials due to its unique molecular structure and electronic properties. For example, it can be used to prepare organic photoelectric materials. With its good photoelectric conversion properties, it shows potential application prospects in organic Light Emitting Diode (OLED), solar cells and other devices. Due to its intramolecular charge transfer properties, fluorescent sensors with high sensitivity to specific molecules or ions can be prepared to achieve rapid detection of environmental pollutants, biomarkers, etc.
    In the field of dye chemistry, the compound often has rich colors due to the presence of conjugated systems in its structure, and can be used as natural or synthetic dyes. Its bright color and good stability have application potential in fabric printing and dyeing, ink manufacturing and other industries, which can endow products with unique colors and excellent light resistance, washing fastness and other properties.
    In conclusion, 5,6-dioxy-1H-indolo-indolo-quinone has important uses in many fields such as medicine, materials, dyes, etc. With the deepening of research, its potential value will continue to be explored and applied.
    What are the physical properties of 5,6-dichloro-1H-benzimidazole
    5,6-Dioxide-1H-indolocarbazole is an extraordinary substance with unique physical properties, with the following numbers:
    The first is the melting point. This substance has a high melting point. Because of its strong intermolecular force, stable structure, and close bonding between atoms, it requires extremely high temperature to disintegrate the lattice, and the molecules break free from bondage and melt.
    and solubility, in common organic solvents, such as ethanol and acetone, its solubility is poor. Due to the molecular structure containing many rigid planes and strong conjugated systems, the polarity is small, and the interaction force with polar organic solvents is weak and difficult to miscible. However, in certain non-polar or weakly polar solvents, such as chloroform and dichloromethane, the solubility is slightly better. Because of its adaptation to the van der Waals force between the molecules of the solvent, it can be moderately dispersed and dissolved.
    The other is density, which is relatively large, resulting from the large number of atoms in the molecule, compact arrangement, and large mass per unit volume. This density characteristic makes it in some mixed systems, due to the action of gravity, there is a specific sedimentation or distribution performance.
    It also discusses stability. It has strong chemical stability, and the intramolecular conjugate structure forms a large π bond. The degree of electron delocalization is high, and the system energy is low. Moreover, the indolocarbazole skeleton structure is rigid, and it is not easy to break bonds and isomerize due to external factors. It can exist stably for a long time The color characteristics of
    cannot be ignored, and it often shows a specific color, which is caused by the transition of electrons in the molecule to absorb the specific wavelength energy of visible light. The existence of the conjugate system makes the energy difference between the excited state and the ground state of the electron in the visible light energy range, so it presents the corresponding color. It can be used as an optical material and has potential value in photochromic, fluorescent display and other fields.
    Is the chemical property of 5,6-dichloro-1H-benzimidazole stable?
    The chemical properties of 5,6-dioxy-1H-indolocarbazole are relatively stable under normal conditions. Due to its unique molecular structure, the molecule contains multiple conjugated systems. This conjugated structure can make the electron cloud distribution more uniform, thereby enhancing the stability of the molecule.
    From the perspective of chemical bonds, the chemical bond energy within the molecule is quite high, and in order to make its chemical bonds break and undergo chemical reactions, it is necessary to supply higher energy. Such as the general acid-base environment, it is difficult to have a significant impact on its structure. Even if heated within a certain temperature range, without specific chemical reaction conditions, its structure can remain relatively stable.
    However, it is necessary to understand that the stability of chemical substances is not absolute. Under extreme conditions, such as high temperature, high pressure and the presence of specific catalysts, or when coexisting with strongly oxidizing and strongly reducing substances, 5,6-dioxy-1H-indolocarbazole may still undergo chemical reactions, causing its chemical structure to change. However, in conventional experimental environments and natural environments, the substance can usually maintain a stable state and does not easily undergo chemical changes.
    What are the synthesis methods of 5,6-dichloro-1H-benzimidazole
    There are several common methods for the synthesis of 5,6-dioxy-1H-indole-carbazole:
    One is to gradually construct the skeleton of the target molecule through a multi-step reaction with appropriate starting materials. First take an aromatic compound with a specific substituent, and use nucleophilic substitution, cyclization and other reactions to form the initial shape of the indole structure. For example, with aromatic hydrocarbons containing amino and halogenated groups, under basic conditions, the amino group undergoes nucleophilic substitution of the halogenated group, and then the ring is closed to form an indole ring. Subsequent modifications are made to the indole ring, by introducing specific groups, such as carbonyl groups at suitable positions, to lay the foundation for the construction of the carbazole structure. < Br >
    Second, the strategy of transition metal catalysis can be adopted. With the help of transition metal catalysts, such as complexes of metals such as palladium and copper, carbon-carbon bonds and carbon-nitrogen bonds can be formed. Taking the coupling reaction catalyzed by palladium as an example, suitable halogenated aromatics and nitrogen-containing nucleophiles are selected. Under the action of palladium catalysts, ligands and bases, a coupling reaction occurs to gradually splice molecular fragments to construct the basic structure of indole-carbazole. During the reaction process, precise regulation of reaction conditions, such as temperature, reaction time, catalyst dosage, etc., has a great impact on the selectivity and yield of the reaction.
    Third, some synthesis routes utilize intramolecular rearrangement reactions. First synthesize a precursor with a specific structure. Under appropriate conditions, the precursor rearranges inside the molecule to form the unique structure of indole and carbazole. This process requires careful design of the structure of the precursor, so that the rearrangement reaction can proceed according to the expected path, and the reaction conditions need to be strictly controlled to ensure the efficiency and selectivity of the reaction. The above synthesis methods have their own advantages and disadvantages. In practical application, the selection should be based on factors such as the availability of starting materials, the difficulty of controlling the reaction conditions, and the purity requirements of the target product.
    What is the price range of 5,6-dichloro-1H-benzimidazole in the market?
    The price range of 5% 2C6-dioxy-1H-benzofuran in the market often varies due to factors such as quality, source, supply and demand.
    If its quality is excellent, the source is orthodox, and the market demand is strong, its price may be high. On the contrary, if the quality is average, the source is mixed, and the market supply is abundant, the price may decrease.
    Roughly speaking, the price per unit of 5% 2C6-dioxy-1H-benzofuran of ordinary quality may be between tens and hundreds of dollars. If the quality is high, finely refined, the impurities are rare, and it is purchased by many workshops and stores, the price may reach hundreds to thousands of dollars per unit.
    However, this is only an approximate price. In the case of inter-market transactions, the final transaction price can only be determined after detailed negotiation between the buyer and the seller depending on the specific circumstances. When the market situation changes, the price also fluctuates, and it is difficult to determine the exact number uniformly.