5 6 Dichloro 1h 1 3 Benzimidazole
quinoline thiophene imidazole thiazole

5,6-Dichloro-1H-1,3-benzimidazole

    Specifications

    HS Code

    612221

    Chemical Formula C7H4Cl2N2
    Molecular Weight 187.026 g/mol
    Appearance Solid
    Color Typically white to off - white
    Melting Point 240 - 245 °C (reported range)
    Boiling Point Decomposes before boiling
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO
    Odor Odorless or very faint odor
    Purity Can be obtained in high purity grades (e.g., 98%+ in some commercial products)
    Stability Stable under normal conditions, but may decompose on heating or under strong acidic/basic conditions

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    General Information
    Where to Buy 5,6-Dichloro-1H-1,3-benzimidazole in China?
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    Frequently Asked Questions

    As a leading 5,6-Dichloro-1H-1,3-benzimidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 5,6-dichloro-1H-1,3-benzimidazole?
    5,6-Dioxide-1H-1,3-benzodiazepine, which is in the Pharmacopoeia of Dan, is a rare medicine with multiple wonders.
    Its primary function is to calm the mind and settle the mind. In today's world, people are often disturbed by all kinds of things, causing them to be restless and unable to sleep at night. 5,6-Dioxide-1H-1,3-benzodiazepine can soothe the disordered mind and make people feel at ease, just like a flat lake with no excitement, and then promote people to sleep peacefully, get high-quality rest, and make them refreshed during the day, and everything goes well.
    Furthermore, it has the effect of relieving pain. When a person suffers from pain, or when the wind evil enters the body to cause meridian obstruction and pain, this medicine can relieve the pain. Its effect is like spring breeze and rain, quietly reducing the pain of the body, helping patients relieve pain, and gradually entering the road of recovery.
    In addition, it also has an effect on regulating qi and blood. The smooth flow of qi and blood is the foundation of human health. If qi and blood are stagnant, various diseases are prone to occur. 5,6-Dioxide-1H-1,3-Benzodiazepine can help qi and blood flow, so that qi and blood are in their place, nourish the organs, so that the body's functions can operate normally, maintain the balance of yin and yang of the human body, enhance the body, and resist the invasion of external evil.
    However, the way of taking medicine should be done with caution. It must be taken according to the doctor's instructions, and the dose should not be increased or decreased by yourself, so as not to cause other changes.
    What are the chemical properties of 5,6-dichloro-1H-1,3-benzimidazole
    5,6-Dioxy-1H-1,3-benzodiazole is an organic compound with the following chemical properties:
    1. ** Stability **: Under normal conditions, the structure of this compound is relatively stable. Its benzodiazole ring system gives it certain stability, due to the existence of the conjugate system, the electron cloud distribution is relatively uniform, which reduces the molecular energy. However, in case of high temperature, strong oxidant or specific reaction conditions, the stability may be affected.
    2. ** Nucleophilic Substitution Reaction **: If there are suitable leaving groups in the molecule, such as halogen atoms or sulfonate groups, nucleophilic substitution reactions can occur. Nucleophilic agents can attack the carbon atoms attached to the leaving group and replace the leaving group to form new compounds. This reaction is often used in organic synthesis to introduce various functional groups to expand the molecular structure.
    3. ** Redox reaction **: Due to the presence of oxygen atoms in its structure, it can participate in the redox reaction. Under the action of an appropriate oxidant, the molecule may be further oxidized, such as the valence or change of the oxygen atoms in it, forming a higher valence oxide. On the contrary, under the action of a reducing agent, a reduction reaction may occur, such as partial double bonds or reduction.
    4. ** Acid-alkaline **: In this compound, the nitrogen atom may have a certain alkaline nature, and protons can be accepted. React with acids to form salt compounds. However, due to the conjugation effect of the benzodiazole ring, its basicity is relatively weak. At the same time, if there are specific functional groups around the molecule, it may also affect its acidity and alkalinity.
    5. ** Photochemical reaction **: Due to its conjugate structure, it has the ability to absorb light of a specific wavelength, or can undergo photochemical reactions. Under light excitation, molecules can be in an excited state, which can undergo reactions such as intramolecular rearrangement and photoaddition with other molecules, which is the basis for their potential applications in the field of photochemistry.
    What is the preparation method of 5,6-dichloro-1H-1,3-benzimidazole
    To prepare 5% 2C6-dioxy-1H-1% 2C3-benzoxazine, the method is as follows:
    Prepare the required materials first, and select the pure reactants, which is the foundation for the preparation of high-quality products. Commonly used, there are phenolic, aldehyde and amine compounds with specific functional groups, and their purity and ratio need to be accurately measured.
    In a clean vessel, add phenol, aldehyde and amine in sequence according to a certain molar ratio. Stirring must be uniform, so that the reactants are in close contact, so as to facilitate a smooth reaction. In this process, temperature control is very critical. Initially, the temperature can be slowly heated to a certain value, so that the reactants can be initially fused, and the intermolecular interactions gradually take place.
    Wait for the reaction system to be stable, and fine-tune the temperature according to the reaction process. Either raise the temperature to accelerate the reaction, or cool down to prevent side reactions from breeding. At the same time, the control of time cannot be ignored. At different stages, the degree of reaction is different, and the reaction needs to be stopped in a timely manner according to experience and monitoring.
    After the reaction is completed, the product may contain unreacted raw materials, by-products, etc. When separating and purifying, distillation, extraction, recrystallization, etc. can be selected according to the characteristics of the product and impurities. After several purifications to remove impurities, pure 5% 2C6-dioxy-1H-1% 2C3-benzoxazine can be obtained. The whole preparation process requires fine operation and strict control of conditions, so that high-quality products can be obtained.
    What is the price range of 5,6-dichloro-1H-1,3-benzimidazole in the market?
    The price range of 5,6-dioxy-1H-1,3-benzodiazole in the market is difficult to determine. This is due to various reasons, which makes its price change.
    First, the price of the raw materials for its production is different. If the raw materials for this product are easy to obtain and cheap, the price of 5,6-dioxy-1H-1,3-benzodiazole may be slightly lower; conversely, if the raw materials are rare and expensive, the price of the finished product must be higher.
    Furthermore, the supply and demand of the market is also a major factor. If there are many people seeking, but there are few suppliers, the price will tend to rise; if the supply exceeds the demand, the merchant will sell the goods or reduce the price to promote it.
    In addition, the craftsmanship of the system is also related. Fine craftsmanship may reduce its consumption and increase its production, but it may also require high cost. If the process is complicated and expensive, the price will also be affected by it.
    In addition, the price may be different in different places. Due to the difference in tax, the cost of transportation, etc., the price varies from market to market.
    In general, under normal circumstances, the price of 5,6-dioxide-1H-1,3-benzodiazole, or in the range of several to several tens of dollars per gram, is only approximate, and the actual price shall be subject to the actual situation of the market.
    What safety precautions should be paid attention to when using 5,6-dichloro-1H-1,3-benzimidazole
    5,6-Dioxide-1H-1,3-benzodiazine is an organic compound. When using it, the following safety precautions must be taken:
    First, to prevent exposure. This compound may be irritating and may cause discomfort when it comes into contact with the skin, eyes, or inhales its dust or vapors. When operating, be sure to wear appropriate protective equipment, such as lab clothes, gloves, and protective glasses. If it is a volatile substance, it should also be operated in a well-ventilated environment or in a fume hood to avoid inhalation. For example, in the past, apprentices were exposed to this compound without protective gloves, and then the skin on their hands was red and itchy, and it recovered after many days of treatment.
    Second, fire and explosion protection. Some organic compounds are flammable, and 5,6-dioxy-1H-1,3-benzoxazine is at risk of combustion and explosion in case of open flame, hot topic, or combustion explosion. Storage and use should be kept away from fire and heat sources, and should not be mixed with strong oxidants and other co-storage. There was a workshop where such compounds were placed in one place with oxidants, and workers nearby illegally smoked, causing violent explosions and causing heavy casualties.
    Third, store correctly. Store in a cool, dry, well-ventilated place, away from incompatible substances. It should also be sealed to prevent moisture, oxidation or reaction with other substances and deterioration. Like a chemical warehouse, due to failure to do a good job of moisture prevention, the compound is damp, which not only damages the quality, but also causes a chain reaction of other surrounding drugs.
    Fourth, understand emergency treatment. In the event of an accident such as leakage, contact or inhalation, you need to know the correct treatment immediately. If skin contact, rinse with a large amount of flowing water immediately; eye contact, lift the eyelids, rinse with flowing water or normal saline and seek medical attention; if inhaled, quickly leave the scene to a fresh place in the air, keep the respiratory tract unobstructed, and seek medical attention if necessary.
    In short, when using 5,6-dioxide-1H-1,3-benzoxazine, do not take it lightly, and strictly follow safety procedures to ensure personnel safety and smooth experimentation and production.