4-(N-phenyl-2-benzimidazole)phenylboronic acid

4- (N-phenyl-2-benzimidazole) phenylboronic acid, an organoboron compound, has a wide range of uses in the field of organic synthesis. Its main ways are as follows:
First, in the Suzuki-Miyaura coupling reaction, it is often used as an important reaction substrate. Suzuki-Miyaura coupling reaction is an effective method for constructing carbon-carbon bonds. 4- (N-phenyl-2-benzimidazole) phenylboronic acid can react with halogenated aromatics or aryl sulfonates in the presence of palladium catalysts and bases to form biaryl compounds with novel structures. Such biaryl compounds have important applications in pharmaceutical chemistry, materials science and many other fields. In drug research and development, biaryl compounds with specific structures may have unique biological activities and can be used as potential drug lead compounds; in the field of materials science, some biaryl compounds can be used to prepare organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices due to their special photoelectric properties.
Second, in terms of building complex organic molecular frameworks, 4- (N-phenyl-2-benzimidazole) phenylboronic acid can participate in multi-step organic synthesis reactions due to its unique structure, and gradually build complex molecular structures. Organic synthesis chemists can skillfully design reaction routes according to the structural requirements of target molecules, and use the compounds to perform selective functional group transformation and linking, thereby synthesizing organic molecules with specific structures and functions. For example, by modifying and reacting its benzimidazole and phenylboronic acid parts, other functional groups can be introduced to further expand the diversity of molecules to meet the needs of specific organic compounds in different fields.

The synthesis method of 4- (N-phenyl-2-benzimidazole) phenylboronic acid is not detailed in the classic "Tiangong Kaiwu", but it can be deduced from the ancient chemical process concept.
First, the compound containing benzimidazole and phenyl can be used as the starting material. First, find the substance with benzimidazole structure, and combine it with boron-containing reagents under appropriate reaction conditions. Among them, a suitable solvent needs to be selected. The ancient preparation often uses water and alcohol as solvents to assist the reaction.
Second, the structure of benzimidazole and phenyl can be gradually constructed. First, benzene is used as the starting point, through halogenation, nitrification and other steps, a specific functional group is introduced, and then through condensation, cyclization and other reactions, the ring system of benzimidazole is constructed. Subsequently, boric acid groups are introduced with boronation reagents. In this process, the control of reaction temperature and time is quite critical. Although ancient chemical operations did not have precise temperature control and time control instruments, they could be regulated according to experience and temperature perception.
Third, natural products are also considered as the starting point and chemically modified to obtain the target product. There are many substances with benzene rings and nitrogen-containing heterocycles in the natural world, which can be extracted, separated, and then chemically introduced into boric acid groups.
When operating, it is necessary to take care of the details of the reaction, such as the ratio of reagents, the cleanliness of the reaction environment, etc. Although there is no precision instrument monitoring today, the process and result of the reaction can be judged by observing the phenomenon of discoloration and gas escape of the reaction. After many attempts and adjustments, 4- (N-phenyl-2-benzimidazole) phenylboronic acid may be obtained.

4- (N-phenyl-2-benzimidazole) phenylboronic acid, this is an organic compound. Its physical and chemical properties are as follows:
Under normal temperature and pressure, it is mostly white to light yellow crystalline powder, just like fine jade chips, delicate and pure. This form is easy to store and use, and also reflects the order of its molecular arrangement to a certain extent.
When it comes to solubility, it shows a unique preference in organic solvents. Common organic solvents such as dichloromethane and chloroform can dissolve well, just like fish entering water and fusing freely. However, in water, the solubility is relatively limited, only slightly soluble. The difference in solubility is due to the characteristics of the organic group and the boric acid group in its molecular structure. The organic part is lipophilic, and the boric acid part has a certain polarity, but the whole is still biased towards the organic phase.
Another melting point, after precise determination, is about 220-225 ° C. When the temperature rises gradually, the thermal motion of the molecule intensifies, the lattice structure begins to disintegrate, and the substance slowly changes from solid to liquid. This melting point characteristic provides an important reference for its synthesis and purification process, and its purity can be judged by melting point measurement.
In terms of chemical properties, the boric acid group gives it Lewis acidity, which can coordinate with electron-rich molecules, just like tenon-mortise contact, to build a new chemical structure. At the same time, the N-phenyl-2-benzimidazole group makes the compound have a certain conjugate system, which shows potential application value in the fields of light and electricity, such as participating in photoluminescence, charge transfer and other processes, just like building a photoelectric bridge in the microscopic world.

4 - (N-phenyl-2-benzimidazole) phenylboronic acid, this compound is in the market, and its price range is difficult to determine. Its price often varies due to many reasons, such as the difficulty of preparation, the price of materials, the amount of demand, and the rise and fall of market conditions.
If it is easy to make, and the required materials are widely distributed and cheap, its price may be inexpensive; on the contrary, if the preparation is cumbersome and the materials used are rare, the price will be high. When demand is high, supply exceeds demand, and the price will also rise; if demand is weak and supply exceeds demand, the price may drop. Changes in market conditions also make its price fluctuate.
To know the exact price, please consult the chemical reagent supplier or check in detail on the relevant chemical trading platform. The prices quoted by different merchants may vary, and more comparisons are required to obtain their approximate price range. And prices often vary from time to time, and real-time market conditions need to be closely monitored.

4- (N-phenyl-2-benzimidazole) phenylboronic acid, the stability of this substance is related to many, and the preparation, storage, and reaction conditions are all affected.
When preparing, if the reaction conditions are not good, such as temperature, pH inappropriateness, or impurity of the product, it will affect the stability. Impurities exist in the product, or promote its degradation or cause other adverse reactions.
Storage is also critical. It is necessary to avoid moisture, heat, and oxygen. In humid environments, water molecules may interact with boric acid groups, causing hydrolysis reactions and destroying molecular structures. High temperature accelerates molecular movement, making chemical bonds easy to break and reducing stability. In the presence of oxygen, it may initiate an oxidation reaction and change the chemical properties of the molecule.
The reaction conditions also affect its stability. Different reaction systems have different pH, solvent characteristics, and proportions of reactants, which may affect their stability in the system. Strong acidic or basic conditions, boric acid groups may react and change their structure. Specific solvents interact with molecules, or promote their decomposition or change their reactivity.
Overall, the stability of 4- (N-phenyl-2-benzimidazole) phenylboronic acid depends on fine control of preparation, storage, and reaction conditions. Negligence in any link may compromise its stability.