4 Methyl 2 Phenyl 1h Imidazole
quinoline thiophene imidazole thiazole

4-Methyl-2-Phenyl-1H-Imidazole

    Specifications

    HS Code

    501348

    Chemical Formula C10H10N2
    Molecular Weight 158.20 g/mol
    Appearance Solid
    Color White to off - white
    Melting Point 144 - 146 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Odor Faint, characteristic organic odor

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    General Information
    Where to Buy 4-Methyl-2-Phenyl-1H-Imidazole in China?
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    Frequently Asked Questions

    As a leading 4-Methyl-2-Phenyl-1H-Imidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Methyl-2-Phenyl-1H-Imidazole?
    4-Methyl-2-phenyl-1H-imidazole is an organic compound. It has a wide range of uses and is important in various fields.
    First and foremost in the field of medicine, this compound is often a key intermediate in drug synthesis. Due to its unique chemical structure, it can interact with specific targets in organisms. For example, in the development of some antibacterial drugs, 4-methyl-2-phenyl-1H-imidazole can be integrated into the molecular structure of the drug through specific chemical reactions to enhance the drug's ability to inhibit or kill pathogens and help fight infectious diseases.
    It can also be seen in the field of materials science. It can be used as a raw material for the preparation of special polymer materials. Through polymerization, its structural units are introduced into the polymer chain to give the material special properties. Such as improving the heat resistance and mechanical strength of the material, or making it have specific optical and electrical properties, so as to meet the strict requirements of high-end fields such as electronic devices and aerospace.
    Furthermore, in the field of organic synthetic chemistry, 4-methyl-2-phenyl-1H-imidazole is often used as a reagent or catalyst for organic synthesis. Because it can promote the progress of specific chemical reactions, such as some catalytic condensation reactions, cyclization reactions, etc., it provides an effective path for the synthesis of complex organic compounds, helping organic chemists to create new compounds and expand the research boundaries of organic chemistry.
    In conclusion, 4-methyl-2-phenyl-1H-imidazole plays an important role in the fields of medicine, materials and organic synthesis due to its unique chemical properties, promoting the development and innovation of technologies in various fields.
    What are the physical properties of 4-Methyl-2-Phenyl-1H-Imidazole?
    4-Methyl-2-phenyl-1H-imidazole, this material has special properties and is related to the field of chemical medicine. Its shape is mostly white to light yellow crystalline powder, and its texture is fine, just like the dust of heaven gathered in one place.
    In terms of its melting point, it is about 160-164 ° C. When the temperature gradually rises, this material melts in the spring sun like ice, and gradually turns from a solid state to a liquid state. The temperature of this phase transition is the key indicator of its physical properties, and it is an important basis for purification and identification.
    Its solubility also has characteristics. In common organic solvents, such as ethanol and dichloromethane, it is quite soluble. Ethanol is like water, and this substance is like salt. When it enters it, it melts and fuses seamlessly. This is due to the attractive force between molecules, which makes it mutually friendly. However, in water, its solubility is very small, and the polarity of water is incompatible with the structural characteristics of 4-methyl-2-phenyl-1H-imidazole, so it is difficult to dissolve, just like oil floating in water, and each does not disturb.
    In terms of stability, this substance is relatively stable at room temperature and pressure, protected from light and dry, such as in a quiet room, holding its state. When encountering strong acids and alkalis, the molecular structure is easily changed by impact, and the chemical properties become active or react to form other substances.
    Although its density is not widely known, it is also one of its physical properties. About 1.15g/cm ³, this value characterizes the mass of its unit volume. Compared with other substances, it can be seen that its weight is dense, and it is necessary to consider the ratio of materials and process design.
    The physical properties of 4-methyl-2-phenyl-1H-imidazole are the cornerstone in the practice of chemical synthesis and pharmaceutical research and development. Only by understanding its physical properties can we make good use of it, so that it can be used in industry and medicine, and it can be used for the benefit of the world.
    What is the chemical synthesis method of 4-Methyl-2-Phenyl-1H-Imidazole?
    To prepare 4-methyl-2-phenyl-1H-imidazole, there are many methods, and the common ones are as follows.
    First, acetophenone and formamide are used as starting materials and can be obtained by cyclization. Take an appropriate amount of acetophenone first, place it in a clean reactor, slowly add formamide, and add a specific catalyst at the same time. This catalyst or a certain acid can promote the smooth progress of the reaction. Heat up to a suitable temperature and keep it for a certain period of time to fully react. This process requires careful regulation of temperature and reaction time. Too high or too low temperature, too long or too short time may affect the purity and yield of the product. After the reaction is completed, the target product can be obtained through various steps such as cooling, separation, and purification.
    Second, 2-phenyl-1H-imidazole can also be used as raw material to react with methylating reagents. Dissolve 2-phenyl-1H-imidazole in a suitable solvent, which needs to have good solubility to both reactants and products and be stable in nature. Then add methylating reagents, such as iodomethane, etc. Alkali substances may be added to the reaction system to promote the reaction. Under appropriate temperature and stirring conditions, the reaction is carried out for a period of time. After the reaction is completed, the impurities are removed by extraction, distillation and other methods, and the product is purified to obtain 4-methyl-2-phenyl-1H-imidazole.
    In addition, there are other synthesis paths, but the above two are more commonly used methods. In practice, the appropriate synthesis method should be carefully selected according to the specific experimental conditions, the availability of raw materials, and the requirements for product purity and yield.
    What is the price range of 4-Methyl-2-Phenyl-1H-Imidazole in the market?
    I look at what you are asking, but I am inquiring about the price range of 4-methyl-2-phenyl-1H-imidazole on the market. However, the price of this product is difficult to determine, and it covers many reasons.
    First, it is about purity. If the purity is very high, it is almost flawless, and the price is high; while the purity is slightly inferior, the price may be slightly reduced. Second, the supply is different, and the price is also different. From a large factory, if the quality is certified, the price is often higher; produced by a small workshop, although the price is low, the quality cannot be fully trusted. Third, the purchase quantity is also a factor. Buy in bulk, merchants may give discounts, and if the quantity is small, the price may be high.
    If you have heard of such substances, those with high purity and small retail quantities, may be up to tens of gold per gram; if purchased in bulk and with moderate purity, they may range from a few gold per gram to more than ten gold. However, these are all approximate numbers. The market conditions change, the price changes at any time, or it may rise or fall due to changes in supply and demand, the price of materials, and the current situation. To know the exact price, you must consult the chemical material supplier, or observe the platform of chemical trading, in order to obtain the actual price.
    What are the relevant safety precautions for 4-Methyl-2-Phenyl-1H-Imidazole?
    4-Methyl-2-phenyl-1H-imidazole is an organic compound that is widely used in many fields, but it involves its safety. The following numbers must be paid attention to:
    First, it is related to toxicity. The toxicity of this compound may vary depending on the route, dose and time of exposure. Oral intake, inhalation or skin contact, or different effects on the human body. Animal experiments or reveal that high doses may cause digestive system disorders, such as nausea, vomiting, diarrhea, etc.; if long-term inhalation of dust or gas containing this compound may damage the respiratory system, cause cough, asthma, or even lung diseases; skin contact or cause allergies, irritation, redness, swelling, and itching. Therefore, when handling this substance, it is necessary to follow the specifications, avoid high concentration exposure, and take good protection.
    Second, the risk of fire and explosion. Organic compounds are flammable, and 4-methyl-2-phenyl-1H-imidazole is also the case. In case of open fire, hot topic, or severe combustion. If mixed with oxidant under specific conditions, there may be a risk of explosion. Storage and use should be kept away from fire and heat sources, and avoid co-storage and co-transportation with strong oxidants. In the place, fire extinguishing equipment must be complete and applicable, and personnel should also be familiar with fire extinguishing methods.
    Third, environmental impact. If this substance is released into the environment, or diffuses, migrates and transforms through different routes, it may have acute and chronic toxicity to aquatic organisms, affecting their growth, reproduction and survival. In the soil, or affect the soil microbial activity and ecological balance. Therefore, when producing, using and disposing, it is necessary to follow environmental regulations to prevent its uncontrolled release into the environment.
    Fourth, operation attention. Access to this substance should be carried out in a well-ventilated place or in a fume hood to reduce the concentration in the air. Operators must wear protective clothing, gloves and goggles to prevent skin and eye contact. Weighing, transferring and other operations, the action should be stable and prevent spillage. Once spilled, it should be handled according to emergency procedures, collect the residue, and clean the contaminated area with appropriate reagents.
    Fifth, storage requirements. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. The packaging must be sealed to prevent moisture absorption and volatilization. Different batches and purity items should be stored in categories and clearly marked. Periodically check the storage environment and containers to see if they have leakage or deterioration.
    In summary, the use of 4-methyl-2-phenyl-1H-imidazole requires a detailed understanding of its safety characteristics and strict operation and management in accordance with safety procedures to ensure the safety of personnel and the environment.