4 Methyl 1h Imidazole 2 Carbaldehyde
quinoline thiophene imidazole thiazole

4-methyl-1H-imidazole-2-carbaldehyde

    Specifications

    HS Code

    558698

    Chemical Formula C5H6N2O
    Molar Mass 110.115 g/mol
    Appearance Solid (usually white or off - white)
    Melting Point Data may vary, typically in a certain range like around 120 - 130 °C (approximate, actual may need precise measurement)
    Solubility In Water Low solubility, due to relatively non - polar nature of the imidazole ring with a hydrophobic methyl group, but may have some solubility as the aldehyde group can participate in some weak hydrogen - bonding
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF, due to favorable interactions between the polar groups of the compound and the solvent molecules
    Pka No exact value given, but imidazole ring has basic nitrogen atoms, and the aldehyde group can influence the acidity/basicity of the molecule, so it would have a characteristic pKa related to its acid - base behavior
    Density Data may need experimental determination, but would be in a range typical for small organic solids based on its molecular weight and packing
    Odor May have a faint, characteristic organic odor related to the imidazole and aldehyde functional groups

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    Frequently Asked Questions

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    What is the chemical structure of 4-methyl-1H-imidazole-2-carbaldehyde?
    In the case of 4-methyl-1H-imidazole-2-carbalaldehyde, its chemical structure can be resolved as follows. In this compound, there is an imidazole ring, which is a five-membered nitrogen-containing heterocycle composed of two nitrogen atoms and three carbon atoms. "1H" shows that the hydrogen atom is attached to the nitrogen atom at position 1 of the imidazole ring. "4-methyl" shows that there is a methyl substituent at position 4 of the imidazole ring, and the methyl group is - CH 🥰, which is single-bonded to the carbon atom of the ring. And "2-carbalaldehyde" means that there is an aldehyde group (CHO) at the second position of the imidazole ring. The carbon and oxygen double bonds in the aldehyde group are connected to the imidazole ring by a single bond, the oxygen has two pairs of lone pairs of electrons, and the hydrogen is connected to the carbon of the aldehyde group by a single bond. The structure of this compound can be confirmed by chemical characterization methods, such as nuclear magnetic resonance, infrared spectroscopy, etc. Its atomic connection mode and spatial arrangement can be confirmed. This structure endows the compound with specific chemical properties, such as aldehyde groups can participate in oxidation, reduction, condensation and other reactions, while the nitrogen atom of the imidazole ring has certain alkalinity and can interact with acids or electrophilic reagents. The existence of methyl groups also affects the physical and chemical properties of molecules, such as molecular polarity and steric resistance.
    What are the main uses of 4-methyl-1H-imidazole-2-carbaldehyde?
    4-Methyl-1H-imidazole-2-formaldehyde, this is an organic compound. It has a wide range of uses and is often used as an intermediate in drug synthesis in the field of medicine. The creation of many drugs depends on the construction of specific chemical structures to give drugs the desired biological activity and pharmacological properties.
    In the field of materials science, it can be used to prepare functional materials. Due to its unique chemical structure, it can react or interact with other substances in a specific manner, thereby improving the properties of materials, such as enhancing their stability, conductivity or optical properties.
    In the field of organic synthesis, it is also an important starting material or intermediate. Chemists can derive many complex organic compounds by performing various chemical reactions on them, such as substitution reactions, addition reactions, etc., which greatly expand the types and functions of organic compounds and provide a rich material basis for chemical research and industrial production.
    In addition, it is also used in the preparation of some fine chemical products, which plays a key role in improving the quality and performance of products. In short, 4-methyl-1H-imidazole-2-formaldehyde plays an indispensable role in many fields and promotes the development and progress of related industries.
    What are 4-methyl-1H-imidazole-2-carbaldehyde synthesis methods?
    The synthesis of 4-methyl-1H-imidazole-2-formaldehyde is a key exploration in the field of organic synthesis. In the past, the method was often achieved by a specific starting material and a multi-step delicate reaction.
    One of the methods can be started from a nitrogen-containing heterocyclic compound. The condensation reaction between it and a specific aldehyde under suitable alkaline environment and catalytic conditions is performed. This reaction requires precise regulation of the ratio of temperature and reactants to ensure the formation of key intermediates. Then, a specific reduction step is applied to the intermediate product to skillfully convert a specific functional group into an aldehyde group, resulting in 4-methyl-1H-imidazole-2-formaldehyde. In this process, the choice of reducing reagents is of paramount importance. Different reagents not only affect the yield of the reaction, but also the purity of the product.
    Another method is to start with imidazole derivatives with suitable substituents. First, the specific position is selectively functionalized, halogenated, or alkylated. Subsequently, the desired methyl group is introduced by means of a metal-catalyzed cross-coupling reaction. Finally, the group at another position is successfully converted to an aldehyde group by a specific oxidation method. In the metal catalysis step, the activity of the metal catalyst, the choice of ligand, and the characteristics of the reaction solvent all have a profound impact on the reaction process and results.
    In addition, there are also attempts to synthesize more concise raw materials by one-pot method. It is about placing several key raw materials in the same reaction system, and by rationally designing the reaction sequence and conditions, they will react in sequence to directly generate the target product. Although this strategy seems simple, to successfully implement it, it is necessary to carefully consider the kinetics and thermodynamics of each step of the reaction to ensure that each reaction is orderly and efficient, and to avoid the excessive occurrence of side reactions. Only in this way can 4-methyl-1H-imidazole-2-formaldehyde be obtained with higher yield and purity.
    What are the physical properties of 4-methyl-1H-imidazole-2-carbaldehyde?
    4-Methyl-1H-imidazole-2-formaldehyde, this substance has unique properties and has many wonders. Looking at its physical properties, at room temperature, it is mostly in a crystalline state, white as snow, just like jade chips. Its melting point is quite critical, and after fine determination, it is about a specific temperature range. This temperature characteristic is very important in separation, purification and other processes, like a guiding light.
    Furthermore, its solubility is also its significant physical properties. In common organic solvents, such as ethanol and acetone, it can show good solubility, just like fish entering water and fusing seamlessly. In water, the degree of solubility is different. Due to the comprehensive influence of polar and non-polar groups in the molecular structure, there is a certain solubility difference. This property is of great significance in the fields of drug preparation and chemical reaction medium selection.
    In addition, the volatility of 4-methyl-1H-imidazole-2-formaldehyde is also worthy of attention. Because of its relatively stable structure and weak volatility, it can maintain its own state for a long time in normal environment, and it is not easy to dissipate and disappear. This point provides convenient conditions for related operations during storage and use, and there is no need to worry too much about the risk of rapid volatilization and content changes. Its physical properties are like a tightly intertwined web, with every detail closely linked to applications in many fields, making it a must-see in chemical research and industrial practice.
    What is the market outlook for 4-methyl-1H-imidazole-2-carbaldehyde?
    4-Methyl-1H-imidazole-2-formaldehyde, an organic compound, has potential applications in many fields, but its market prospects still depend on many factors.
    It is first mentioned in the field of medicine. With the advance of pharmaceutical research and development, the demand for novel active compounds is increasing. 4-Methyl-1H-imidazole-2-formaldehyde may be used as a key intermediate for the synthesis of drugs with special pharmacological activity. For example, in the development of anti-tumor drugs, it may provide a cornerstone for the construction of specific molecular structures, which will help to develop new anti-cancer drugs with better efficacy and fewer side effects. The demand in this field is growing, and a broad market space is opened up for it.
    Looking at pesticides again. At present, there is a high voice for high-efficiency, low-toxicity and environmentally friendly pesticides. With this compound as raw material, new pesticides may be created, which have a unique mechanism of action and can effectively control pests and diseases, and have little impact on the ecological environment. If the research and development is successful and promoted, the market potential is huge.
    In the field of materials science, it also has potential. With the development of science and technology, there is a growing demand for special performance materials. 4-Methyl-1H-imidazole-2-formaldehyde or participate in the synthesis of materials with special optical, electrical or mechanical properties, used in electronic devices, optical instruments and other fields.
    However, its marketing activities also face challenges. The complexity and cost of the synthesis process have a great impact on large-scale production and market competitiveness. If the process is cumbersome and costly, it will limit its market expansion. And regulations and policies have strict requirements on the safety and environmental protection of compounds, and relevant standards must be met before entering the market.
    Overall, 4-methyl-1H-imidazole-2-formaldehyde faces challenges, but with potential applications in medicine, pesticides, materials science and other fields, if the synthesis and regulatory problems can be overcome, the market prospect is bright.