4 Hydroxymethylimidazole
quinoline thiophene imidazole thiazole

4-HYDROXYMETHYLIMIDAZOLE

    Specifications

    HS Code

    836794

    Name 4-HYDROXYMETHYLIMIDAZOLE
    Chemical Formula C4H6N2O
    Molecular Weight 98.10 g/mol
    Appearance White to off - white solid
    Melting Point 160 - 164 °C
    Solubility In Water Soluble
    Pka Around 14.5 (approximate value for imidazole ring)
    Stability Stable under normal conditions, but may react with strong oxidizing agents
    Odor Odorless (or very faint odor)

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    General Information
    Where to Buy 4-HYDROXYMETHYLIMIDAZOLE in China?
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    Frequently Asked Questions

    As a leading 4-HYDROXYMETHYLIMIDAZOLE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-HYDROXYMETHYLIMIDAZOLE?
    4-Hydroxymethylimidazole, an organic compound, has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. Taking an antibacterial drug as an example, through a specific chemical reaction, 4-hydroxymethylimidazole can participate in the construction of the active structure of the drug, enhance the antibacterial efficacy of the drug, and help the human body resist the invasion of pathogens.
    In the field of materials science, its role should not be underestimated. It can be used to prepare high-performance polymer materials. By polymerizing with other monomers, it gives the material unique properties, such as improving the heat resistance and stability of the material, so that it can still maintain good performance under high temperature or complex environments. It is used in aerospace and other fields that require strict materials. < Br >
    In the field of chemical production, it is often used as a catalyst or auxiliary agent. In some organic synthesis reactions, it can significantly accelerate the reaction rate, improve the reaction efficiency and yield, reduce the reaction time and cost, and then promote the efficient production of chemical industry, which contributes to the development of industry.
    In biochemical research, it also has important value. It can be used as a biological probe to label biomolecules, helping scientists to deeply explore the complex biochemical processes in organisms, clarify the mysteries of life activities, and provide strong support for the development of biomedicine.
    In conclusion, 4-hydroxymethyl imidazole plays a key role in many fields due to its diverse and important uses, and has a profound impact on human life and technological progress.
    What are the physical properties of 4-HYDROXYMETHYLIMIDAZOLE?
    4-Hydroxymethylimidazole is one of the organic compounds. Its physical properties are quite important and have unique characteristics.
    This compound is either solid at room temperature, looking at its shape, or in the shape of white crystals. Its appearance is pure, uniform and delicate, quite like snow frost. The value of its melting point is one of the key physical properties, and it is about a specific temperature range. This temperature limit is of great significance for the identification and purification of this substance. Because the melting point is relatively fixed, it can be accurately determined by melting point to judge the purity.
    In addition, 4-hydroxymethylimidazole also has characteristics in terms of solubility. It exhibits different degrees of solubility in many organic solvents. In polar organic solvents, such as ethanol, it can be moderately dissolved. Ethanol molecules are polar, and they interact with 4-hydroxymethylimidazole molecules through intermolecular forces, such as hydrogen bonds, to promote their dissolution. In non-polar organic solvents, such as n-hexane, the solubility is poor, because the molecular structure and the molecular force of non-polar solvents are weak and difficult to miscible.
    Its density is also one end of physical properties. Although the specific value varies slightly due to measurement conditions, it is roughly within a certain range. This density value has important reference value in practical operations such as separation and mixing of the substance.
    And the stability of the compound is also a key point for physical property consideration. Under normal environmental conditions, 4-hydroxymethylimidazole has certain chemical stability. However, under special conditions, such as high temperature, strong acid and alkali environment, its structure may change and its stability will be damaged. This stability is critical for the setting of its storage and use conditions. It needs to be stored in a suitable environment to maintain the stability of its chemical structure and properties, so that it can be effectively used in various chemical synthesis and related application fields.
    What are the chemical properties of 4-HYDROXYMETHYLIMIDAZOLE?
    The chemical properties of 4-hydroxymethylimidazole are specific, and it is worth exploring. This substance has a certain stability, and can maintain the relative stability of its own structure at room temperature. In case of specific chemical reagents, it will also show active reactivity.
    It is hydrophilic, and because of the presence of hydroxymethyl groups, the molecule is easy to interact with water and can be dissolved in polar solvents. And the hydroxyl group of hydroxymethyl groups can participate in many chemical reactions, such as esterification reactions, which can be esterified with acids under appropriate conditions to form corresponding ester products.
    And because of the conjugated structure of the imidazole ring, 4-hydroxymethylimidazole is endowed with a certain electron cloud distribution characteristics, which affects its chemical activity. In an alkaline environment, the nitrogen atom of the imidazole ring can accept protons and exhibit a certain alkalinity; in an acidic environment, a corresponding protonation reaction will also occur, resulting in changes in the charge distribution and chemical properties of the molecule.
    In addition, the hydroxymethyl group of 4-hydroxymethylimidazole can be oxidized to form an aldehyde group or even a carboxyl group. This oxidation reaction can occur under the action of a specific oxidant, and the reaction process and product are strictly restricted by reaction conditions, such as temperature, reaction time, and the amount and type of oxidant.
    What is 4-HYDROXYMETHYLIMIDAZOLE production method?
    4-Hydroxymethylimidazole can be synthesized by various methods. One of the commonly used methods is the reaction of formaldehyde and glyoxal under the catalysis of ammonia or amine compounds. In this process, formaldehyde and glyoxal combine and undergo a series of chemical changes to gradually generate 4-hydroxymethylimidazole. During the reaction, temperature, the proportion of reactants and the amount of catalyst are all crucial. If the temperature is too high, it may cause side reactions and lead to impure products; improper proportions also affect the yield.
    In addition, other raw materials are also prepared by multi-step reaction. For example, with specific nitrogen-containing compounds and hydroxyl-containing compounds, the condensation reaction is first carried out, and then the modification and transformation steps are carried out to obtain 4-hydroxymethylimidazole. Although this path is more complicated, the reaction conditions and steps can be flexibly adjusted according to actual needs to obtain products with higher purity and yield.
    There are also attempts to synthesize by microbial fermentation method. Screen specific microbial strains and culture them in a suitable medium. During the growth and metabolism process, microorganisms can synthesize 4-hydroxymethylimidazole through their own metabolic pathways. This biosynthetic method has the advantages of green environmental protection, but it also faces challenges such as difficulty in screening strains and harsh fermentation conditions. < Br >
    All these methods have advantages and disadvantages. In actual production, it is necessary to comprehensively consider the cost of raw materials, product purity, production efficiency and many other factors to choose the most suitable production method.
    4-HYDROXYMETHYLIMIDAZOLE what are the precautions during use
    4-Hydroxymethylimidazole is a very important chemical substance. During use, many precautions must be paid attention to.
    Those who bear the brunt must be fully protected. This substance may be irritating to a certain extent, and when exposed, be carefully protected. When operating, appropriate protective equipment must be worn, such as protective glasses, gloves and protective clothing. To prevent it from accidentally touching the skin and eyes, if it comes into contact, rinse with plenty of water immediately, and seek medical attention in a timely manner according to the actual situation.
    Furthermore, the storage process cannot be ignored. It is advisable to store it in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties, if improperly stored or deteriorated, it may even cause safety accidents. And it should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed with storage to prevent dangerous chemical reactions.
    The use environment is also exquisite. The operating site should have good ventilation conditions to avoid the accumulation of its volatile gas in the air to prevent inhalation from endangering health. During the use process, strictly follow the specified operating procedures, precisely control the dosage, and do not increase or decrease at will.
    In addition, after use, properly dispose of the remaining 4-hydroxymethymethylimidazole and related waste. Do not discard at will, follow relevant environmental regulations, and dispose of it in a correct way to avoid pollution to the environment. Thus, to ensure the use of 4 - hydroxymethylimidazole process safety, compliance and environmental protection.