4-(HYDROXYMETHYL)-1H-IMIDAZOLE

4- (hydroxymethyl) -1H-imidazole is one of the organic compounds. Its chemical properties are unique and have many wonderful properties.
This compound contains an imidazole ring, with hydroxymethyl groups attached to the fourth position of the ring. The imidazole ring is aromatic, making it stable to a certain extent. The presence of hydroxymethyl groups gives it hydrophilicity. Because the hydroxyl group can form hydrogen bonds with water molecules, the substance has a certain solubility in water.
Furthermore, the hydroxyl group has active chemical activity. It can participate in many chemical reactions, such as esterification reactions. When encountering carboxylic acids, under suitable conditions, the hydrogen atom of the hydroxyl group can remove a molecule of water from the carboxylic group of the carboxylic acid to form an ester bond. This reaction can be used to prepare various derivatives containing ester groups, which is of great significance in the field of organic synthesis.
At the same time, hydroxymethyl groups can also undergo oxidation reactions. Moderate oxidation can convert them into aldehyde or carboxyl groups, resulting in significant changes in the chemical properties and functions of compounds. For example, after oxidation to aldehyde groups, the substance can participate in nucleophilic addition reactions, react with nucleophilic reagents such as nitrogen and sulfur, and generate new compounds, expanding its application range.
In addition, the nitrogen atom on the imidazole ring has a lone pair electron, which can coordinate with metal ions to form metal complexes. This property has attracted much attention in the field of catalysis and can be used as a ligand to enhance the activity and selectivity of metal catalysts. The unique chemical structure of 4- (hydroxymethyl) -1H-imidazoline shows hydrophilicity, reactivity of hydroxyl groups, coordination ability of imidazole ring and other chemical properties, which has potential application value in organic synthesis, materials science, catalysis and many other fields.

4- (hydroxymethyl) -1H-imidazole has a wide range of uses and is useful in various fields.
In the field of medicine, it is a key intermediate. It can be used to create a variety of drugs, or to help regulate human physiological functions, or to cure various diseases. With its special chemical structure, it can interact with molecules in the body to achieve specific pharmacological effects. Or participate in the synthesis of antibacterial drugs to fight the invasion of pathogenic microorganisms; or be used to develop drugs related to the nervous system to help improve nervous function.
In the context of materials science, it also has its uses. It can be used as a monomer to participate in the synthesis of polymer materials, giving materials different properties. Such as enhancing the stability of materials and improving their mechanical properties. Because it contains active groups, it can react with other compounds to construct a material system with unique properties, which is used in aerospace, automobile manufacturing and other fields to meet the demand for high-performance materials.
In organic synthetic chemistry, 4- (hydroxymethyl) -1H-imidazole is also a commonly used reagent. With its unique reactivity, it can participate in many organic reactions and provide an effective way for the synthesis of complex organic compounds. It can be used to construct important chemical bonds such as carbon-nitrogen bonds, enabling chemists to create organic molecules with novel structures and functions, and promoting the development of organic synthetic chemistry. < Br >
And in the field of catalysis, it also shows certain potential. It can be used as a ligand to complex with metal ions to form an efficient catalyst, which can promote the progress of various chemical reactions, improve the reaction rate and selectivity, and play an important role in chemical production to optimize the production process and reduce costs.

To prepare 4- (hydroxymethyl) -1H-imidazole, the following method can be used.
First, a suitable starting material is obtained, usually starting with a compound containing the corresponding functional group. If a nitrile or amide compound with a suitable substituent is used as a starting material, this is because the nitrile or amide group can be specially converted to introduce the desired hydroxymethyl and imidazole ring structural unit.
First, the starting material is subjected to a specific reaction to initially construct the precursor structure of the imidazole ring. This step may require a suitable reagent to promote cyclization under specific reaction conditions. For example, basic reagents can be used to assist in condensation and cyclization in molecules, so that the atoms can be rearranged and combined to form the basic skeleton of the imidazole ring.
Wait until the imidazole ring skeleton is initially formed, and then introduce hydroxymethyl groups. Suitable hydroxymethylation reagents, such as formaldehyde and related derivatives, can be selected to react with them under suitable reaction conditions. During the reaction, factors such as reaction temperature, pH and reaction time need to be carefully adjusted to ensure that hydroxymethyl groups are accurately introduced into the target position and there are few side reactions.
During the reaction process, each step needs to be monitored in detail. A variety of analytical methods, such as thin-layer chromatography, can be used to observe the reaction progress in real time, and follow-up operations can be determined according to the reaction progress. When the reaction reaches the desired level, the product is separated and purified. Column chromatography, recrystallization and other means are often used to remove impurities to obtain pure 4- (hydroxymethyl) -1H-imidazole. In this way, the target compound can be obtained through multiple steps of delicate operation.

I have not obtained the exact number of 4- (hydroxymethyl) -1H-imidazole in the market price range. However, if you want to know its price, you can find it in various ways.
First, you can explore the chemical raw material trading platform. In today's world, the Internet is prosperous, and many chemical products can be found on the online platform. On the platform, you can see the price quoted by various suppliers for this product. The price varies depending on the supplier and quantity.
Second, you can ask the chemical raw material supplier. Many suppliers specialize in the trading of chemical products, and they are familiar with market conditions. Call or write to them to inquire about the price of 4- (hydroxymethyl) -1H-imidazole. He must give an approximate price according to the current situation.
Third, look at industry reports and information. The chemical industry often publishes reports to keep track of the market dynamics of various products, which may include price trends. Reading such information can also give a general solution to the price of 4- (hydroxymethyl) -1H-imidazole.
I regret that I cannot directly state the price range, but according to this method, I must be able to obtain the confidence of its market price range.

4- (hydroxymethyl) -1H-imidazole should be stored in a cool, dry and well-ventilated place. This material may be sensitive to heat and humidity, so it is important to avoid high temperature and humid places.
Its storage should be kept away from fire and heat sources, and should not be mixed with oxidizers, acids, etc. In case of such substances, or a violent reaction, it will cause a danger to the situation.
The storage device must be tightly sealed to prevent it from changing in contact with air. After taking it, it should also be sealed immediately to prevent it from being disturbed by the outside world.
In the storage place, appropriate fire protection and leakage emergency response equipment should be prepared. If there is a risk of leakage, timely response measures can be taken to prevent the spread of the scourge. And the storage place should be clearly marked, so that people can know at a glance where it is stored, how to store it, and what to do in case. In this way, 4- (hydroxymethyl) -1H-imidazole storage is safe and ready for timely use.