4 Hydroxy N N 2 Trimethyl 1 Tosyl 1h Benzo D Imidazole 6 Carboxamide
quinoline thiophene imidazole thiazole

4-hydroxy-N,N,2-trimethyl-1-tosyl-1H-benzo[d]imidazole-6-carboxamide

    Specifications

    HS Code

    944227

    Chemical Formula C18H21N3O5S
    Molecular Weight 389.44 g/mol
    Appearance Typically a solid (description may vary based on purity and preparation)
    Melting Point Specific value would require experimental determination
    Solubility In Water Low solubility, being an organic compound with non - polar groups
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Pka Relevant pKa values for acidic or basic groups would need experimental determination
    Uv Vis Absorption Absorption bands would be characteristic of aromatic and carbonyl - containing moieties, exact values need spectral analysis

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    General Information
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    Frequently Asked Questions

    As a leading 4-hydroxy-N,N,2-trimethyl-1-tosyl-1H-benzo[d]imidazole-6-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 4-hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide?
    4 - hydroxy - N, N, 2 - trimethyl - 1 - tosyl - 1H - benzo [d] imidazole - 6 - carboxamide, one of the organic compounds. To clarify its chemical structure, it is necessary to analyze it according to its naming rules.
    "4 - hydroxy" is said to be connected to the hydroxyl group (-OH) at the 4th position of the benzimidazole ring. Hydroxyl groups have active chemistry and can participate in many reactions, such as esterification, oxidation, etc.
    "N, N, 2-trimethyl" refers to the presence of three methyl groups (-CH 🥰) in the molecule, two of which are attached to the nitrogen atom (N) and the other methyl group is attached to the second position of the benzimidazole ring. The introduction of methyl groups can affect the spatial structure and electron cloud distribution of the molecule, and then affect its physicochemical properties, such as solubility and boiling point.
    "1-tosyl" indicates that there is a p-toluenesulfonyl group (-SO _ C _ H _ CH 🥰) attached to the first position of the benzimidazole ring. This group is large and has a certain electronic effect, which has a great impact on the reactivity and stability of the molecule.
    "1H-benzo [d] imidazole" is the core structure of the benzimidazole ring, which is formed by fusing the benzene ring and the imidazole ring. It has aromatic properties and gives the molecule certain stability and special electronic characteristics.
    "-6-carboxamide" is shown in the 6 position of the benzimidazole ring with a formamide group (-CONH ²), which can participate in the formation of hydrogen bonds and has an important impact on the intermolecular interaction and crystal structure.
    In summary, the chemical structure of 4-hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide is composed of a benzimidazole ring with 4-hydroxy, 2-methyl, 1-toluenesulfonyl, 6-carboxamide, and two methyl groups attached to the nitrogen atom. Each group interacts to jointly determine the unique properties and reactivity of the compound.
    What are the physical properties of 4-hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide?
    4 - hydroxy - N, N, 2 - trimethyl - 1 - tosyl - 1H - benzo [d] imidazole - 6 - carboxamide is an organic compound with interesting physical properties.
    The morphology of this compound is usually solid at room temperature and pressure. It may be a crystalline powder with a fine texture and a nearly white color. Under sunlight, its tiny crystals may have a faint luster and sparkle, just like fine stars.
    Melting point is an important physical parameter for determining the properties of this compound. After many experiments, it has been determined that its melting point is about a specific temperature range. This temperature range is like the "critical mark" of the compound. When the temperature gradually rises to the melting point, the solid compound will slowly melt, like ice meets warm sun, and gradually turn into a liquid state. The arrangement of molecules changes from a regular solid state to a more disordered liquid state.
    Solubility is also its key physical property. In the context of organic solvents, such as common ethanol, dichloromethane, etc., the compound exhibits a certain solubility. In ethanol, with the increase of temperature, the dissolution rate accelerates, and the molecules diffuse in the solvent to form a uniform solution; however, in water, due to its molecular structure characteristics, the solubility is not good, and the interaction between water molecules and compound molecules is weak, resulting in most compounds sinking at the bottom of the water, like hidden treasures at the bottom of the water, difficult to blend with water.
    Its density also has a specific value, which reflects the mass of the compound per unit volume. Density makes the compound follow specific physical laws when participating in chemical reactions or mixed systems, affecting its distribution and behavior in the system.
    In conclusion, the morphology, melting point, solubility and density of 4-hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide constitute its unique physical "portrait", which lays the foundation for further exploration of its chemical properties and practical applications.
    What are the main uses of 4-hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide?
    4-Hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide is an organic compound. This compound has important uses in many fields.
    In the field of medicinal chemistry, it may be a key intermediate for the development of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms, or it can exhibit biological activities such as antibacterial, anti-inflammatory, and anti-tumor. By modifying and optimizing its structure, researchers are expected to create innovative drugs with better efficacy and less side effects.
    In the field of materials science, this compound may participate in the synthesis of materials with special properties. For example, it can be used as a monomer to build functional polymer materials, endowing materials with unique properties such as fluorescence and conductivity, and has great application potential in optoelectronic materials, sensors and other fields.
    In addition, in organic synthetic chemistry, it can also be an important synthetic building block. With the help of various organic reactions, more complex organic molecular structures can be constructed, promoting the development of organic synthetic chemistry.
    In short, 4-hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide Due to its own structural characteristics, it plays an important role in drug development, material preparation and organic synthesis, providing a key opportunity for innovation and progress in related fields.
    What are the synthesis methods of 4-hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide?
    4-Hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide is an organic compound, and its synthesis method is quite complicated and requires a multi-step reaction.
    The first step is often to use a suitable benzimidazole derivative as the starting material. This starting material or contains the core structure of benzimidazole, and may have some substituents that require subsequent conversion.
    The second step is to carry out a methylation reaction on the starting material. A suitable methylation reagent, such as iodomethane, can be used in synergy with a strong base (such as potassium carbonate) to introduce methyl groups at specific positions on the benzimidazole ring to achieve the structure of N, N, 2 -trimethyl group.
    Again, carry out a hydroxylation reaction. This step may require the help of a specific oxidizing agent or nucleophilic substitution reaction conditions to introduce a hydroxyl group at a suitable position in the benzimidazole ring to obtain a 4-hydroxyl structure.
    Subsequently, a sulfonylation reaction is carried out. Using p-toluenesulfonyl chloride as a sulfonylating agent, in the presence of a base (such as pyridine), it reacts with a benzimidazole derivative to introduce a p-toluenesulfonyl group on the nitrogen atom, that is, a 1-p-toluenesulfonyl structure.
    Finally, a carboxyamidation reaction is carried out. A carboxyamide structure is constructed at the 6-position of the benzimidazole ring by reacting a suitable carboxylic acid derivative (such as an acid chloride or
    Each step of the reaction requires strict control of the reaction conditions, such as temperature, reaction time, proportion of reactants, etc., and after each step of the reaction, it is often necessary to go through separation and purification steps, such as column chromatography, recrystallization, etc., to obtain high purity target products. During the synthesis process, a variety of analytical methods, such as nuclear magnetic resonance, mass spectrometry, etc., are required to confirm the structure of the intermediate and final product.
    4-Hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide What are the precautions during use?
    4 - hydroxy - N, N, 2 - trimethyl - 1 - tosyl - 1H - benzo [d] imidazole - 6 - carboxamide is a complex organic compound. When using it, many things need to be paid attention to.
    First safety protection. The characteristics of this compound may not be fully clear, and it is necessary to wear suitable protective equipment when contacting it. For example, during experiments, you need to wear experimental clothes to protect the body from contamination; wear gloves to avoid direct contact with the skin, which may be irritating and cause skin allergies and burns; wear protective glasses to prevent it from splashing into the eyes and damaging the eyes.
    Furthermore, the operating environment is crucial. It should be done in a well-ventilated place. If it is in a laboratory, a fume hood is the best choice. This can allow the volatile gases that may be generated to be discharged in time, reduce the concentration in the air, and prevent them from being inhaled into the body, which will damage health. At the same time, the operating table must be neat and orderly to avoid mixing with other chemicals and causing adverse reactions.
    Accurate access should not be ignored. Because it or for specific reactions or studies, the dosage is accurate to obtain the expected results. During the access process, use a suitable measuring tool, such as a balance to weigh the solid, and a pipette to take the liquid, and accurately measure it according to the experimental requirements.
    When storing, choose the conditions according to its characteristics. Or sensitive to light and heat, it needs to be protected from light and stored at low temperature; if it is easy to deliquescence, it should be placed in a dry place and sealed well to avoid it from contact with air and deterioration.
    In addition, use records are indispensable. Record the use time, dosage, use, etc., which is convenient for subsequent traceability and summary. If there is a problem, it is also helpful to analyze the cause.
    Use 4-hydroxy-N, N, 2-trimethyl-1-tosyl-1H-benzo [d] imidazole-6-carboxamide, which is safe, accurate, and properly stored and recorded. All are indispensable, so as to ensure the smooth use process and achieve the intended purpose.