4 5 Methyl 2 Mercapto Benzimidazole
quinoline thiophene imidazole thiazole

(4,5)-methyl-2-mercapto benzimidazole

    Specifications

    HS Code

    316066

    Chemical Formula C9H10N2S
    Molecular Weight 178.25
    Appearance Solid
    Color Off - white to light yellow
    Odor Characteristic sulfur - like odor
    Melting Point 176 - 178 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, acetone
    Pka Value Around 6.5
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

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    What is the main use of (4,5) -methyl-2-mercapto benzimidazole?
    (4,5) -Methyl-2-mercaptobenzimidazole, its main use is very important. This compound is used in many fields.
    In the field of medicine, it shows unique medicinal value. Due to its structural properties, it can be used as a key intermediate for some drugs. Through specific chemical reactions, pharmaceutical ingredients with antibacterial and antiviral effects can be derived. With such derived drugs, it can effectively resist the damage of various bacteria to the human body and escort human health.
    In the field of materials science, (4,5) -methyl-2-mercaptobenzimidazole also plays a role that cannot be ignored. It can be used as an additive and incorporated into specific materials. In this way, the properties of the material can be significantly improved, such as enhancing the stability of the material and improving its oxidation resistance. The material can maintain good physical and chemical properties in different environments, thus broadening the application range of the material.
    Furthermore, in industrial production, this compound can be used in the preparation of catalysts. With its special chemical activity, it can accelerate the process of specific chemical reactions, improve production efficiency and reduce production costs. In many industrial links such as chemical synthesis, with its unique properties, it helps the smooth progress of industrial production and contributes to industrial development.
    In summary, (4,5) -methyl-2-mercaptobenzimidazole plays a pivotal role in many key fields such as medicine, materials science, and industrial production, and has a wide range of important uses.
    What are the physical properties of (4,5) -methyl-2-mercapto benzimidazole
    (4,5) -Methyl-2-mercaptobenzimidazole is a kind of organic compound. Its physical properties are quite important and are considered in scientific research and industrial applications.
    Looking at its properties, it is mostly crystalline solids under normal conditions. This is due to the characteristics of molecular structure and the interaction between molecules. Its color is usually white to light yellow, and the color is relatively light, which is related to the absorption and reflection characteristics of the molecule.
    When it comes to melting point, (4,5) -methyl-2-mercaptobenzimidazole has a specific melting point value, which is about [X] ℃. The existence of the melting point is due to the fact that when the temperature rises, the molecule obtains enough energy to overcome the lattice energy and cause the solid state to transform into a liquid state. The characteristics of this melting point are of critical significance for the purification, identification and temperature control of substances during application.
    In terms of solubility, it has different solubility in common organic solvents. In some organic solvents such as ethanol and acetone, it can exhibit certain solubility, because the molecules and solvent molecules can form interactions such as hydrogen bonds and van der Waals forces, so that it can be dispersed in the solvent. However, in water, its solubility is poor, because the hydrophobic part of the compound molecule is large, and the interaction with water molecules is weak, making it difficult to form a stable dispersion system.
    In addition, the density of the compound is also one of its physical properties, and its density is about [X] g/cm ³. The density reflects the mass per unit volume of the substance. In practical applications, such as solution preparation, material separation, etc., the density data is helpful for accurate calculation and operation.
    In short, the physical properties of (4,5) -methyl-2-mercaptobenzimidazole, such as crystalline solid morphology, specific melting point, solubility and density, are indispensable basic information in chemical research, chemical production and related application fields, laying the foundation for further exploration of its chemical properties and applications.
    What are the chemical properties of (4,5) -methyl-2-mercapto benzimidazole
    (4,5) -Methyl-2-mercaptobenzimidazole, this is an organic compound with unique chemical properties. Its molecule contains a core structure of benzimidazole, with methyl added at the 4th and 5th positions and a thiol group at the 2nd position.
    Looking at its physical properties, it may be a solid under normal conditions, and the melting boiling point varies depending on the force between molecules. Due to the benzene ring, the structure has a certain stability, and the melting boiling point is not low. Molecular polarity is affected by substituents. The polarity of thiol groups is higher, and the weak electron donor of methyl groups affects the overall charge distribution and polarity of molecules, which in turn affects the solubility, and may have a certain solubility in polar solvents.
    When it comes to chemical properties, thiol groups have high activity and can participate in many chemical reactions. It is easy to oxidize and form disulfide bonds. This property is of great significance for the maintenance of the structure and function of biomolecules such as proteins and polypeptides. Under basic conditions, thiol hydrogens are easy to dissociate, acidic, and can complex with metal ions to form stable complexes for metal ion detection, separation and purification. The benzimidazole ring is aromatic and can undergo electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. The localization effect of the substituent depends on the reaction conditions and reagents. In addition, the compound may have certain biological activities and may have potential applications in the fields of medicine and pesticides. For example, as a drug lead compound, it can be structurally modified to develop drugs with specific pharmacological activities.
    What are the synthesis methods of (4,5) -methyl-2-mercapto benzimidazole
    The synthesis method of (4,5-methyl-2-mercaptobenzimidazole), although the ancient book "Tiangong Kaiwu" does not directly describe the synthesis of this substance, it can be deduced from many chemical synthesis principles contained in the book.
    Synthesize this substance in the past, or take a suitable benzimidazole matrix first, choose a suitable reaction vessel, use copper salt or other metal salts as catalysts, add an appropriate amount of methylation reagents, such as iodomethane or dimethyl sulfate. At a certain temperature and reaction time, the methyl group is successfully connected to the 4th and 5th positions of benzimidazole. During the reaction, careful temperature control is required. If the temperature is too high, side reactions will occur, and if it is too low, the reaction will be slow.
    After methylation is completed, a sulfhydryl group is introduced. Sodium hydrosulfide or thiourea and other sulfur-containing reagents are often used in alkaline environments, such as sodium hydroxide or potassium hydroxide solutions, through ingenious reactions, the sulfhydryl group is successfully connected to the 2 positions of benzimidazole. In this process, the control of the pH of the solution is crucial, and the alkalinity is too strong or too weak, which affects the effectiveness of the mercapylation reaction.
    In addition, it is also used as the starting material of o-phenylenediamine and carbon disulfide to first condensate to form benzimidazole-2-thione intermediates, and then methylation is carried out to achieve methylation at the 4th and 5th positions. This approach also requires careful study of the reaction conditions of each step, such as the choice of reaction solvent and the proportion of reactants, etc., in order to make the synthesis reaction smooth and obtain the target product (4,5-methyl-2-mercaptobenzimidazole).
    What are the precautions for (4,5) -methyl-2-mercapto benzimidazole during use?
    (4,5) -Methyl-2-mercaptobenzimidazole is an important chemical substance, and there are several precautions to be kept in mind during use.
    First, safety protection must be comprehensive. This substance may be harmful to the human body. When exposed, wear appropriate protective equipment, such as gloves, protective glasses and protective clothing, to avoid direct contact with the skin and eyes. If inadvertently exposed, rinse with plenty of water immediately and seek medical attention according to the specific situation.
    Second, storage conditions also need to be paid attention to. It should be stored in a cool, dry and well-ventilated place, away from fire sources and oxidants. Because it has certain chemical activity, improper storage or deterioration can even cause safety accidents.
    Third, when using, the operating specifications cannot be ignored. It is necessary to strictly follow the established operating procedures to precisely control the dosage and reaction conditions. Because the chemical reaction involved may be more complex, a slight deviation in the conditions may affect the reaction effect and even generate harmful by-products.
    Fourth, waste disposal must also be in compliance. The remaining substances and waste after use must not be discarded at will, and must be properly disposed of in accordance with relevant environmental regulations to prevent pollution to the environment.
    In conclusion, the use of (4,5) -methyl-2-mercaptobenzimidazole requires careful attention to safety, storage, handling, and disposal in order to ensure the safety and efficiency of the use process.