4(5)-iodo-2-methyl-1H-imidazole

4- (2- (5-iodine-2-methyl-1H-imidazole-1-yl) ethyl) morpholine, this compound has important uses in the field of pharmaceutical research and development.
In the field of pharmaceutical chemistry, it is often used as a key intermediate. By ingeniously modifying the structure of this compound, a series of derivatives with unique pharmacological activities can be constructed ingeniously. Taking the development of specific anticancer drugs as an example, researchers have carefully spliced it with other active groups to successfully create new compounds that can precisely target specific receptors or signaling pathways in cancer cells. These new compounds are like precision-guided "missiles" that can effectively inhibit the proliferation and spread of cancer cells, opening up a new path for the development of anti-cancer drugs.
In the field of neurological drug research, it has also emerged. After in-depth investigation, scientists found that after optimizing its structure, the obtained derivatives can have a positive impact on the metabolism and transmission of neurotransmitters. Some derivatives are like a precise "key" that can specifically act on specific targets on the surface of nerve cells, modulate the excitability and inhibition of nerve cells, and then provide potential effective drug lead compounds for the treatment of difficult neurological diseases such as Parkinson's disease and Alzheimer's disease.
In the field of organic synthetic chemistry, 4- (2- (5-iodine-2-methyl-1H-imidazole-1-yl) ethyl) morpholine is also a commonly used synthetic block. Due to its unique molecular structure and reactivity, it can be skillfully combined with many different types of organic compounds through various classical organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc., to build complex and diverse organic macromolecules. Like building building blocks, it provides an indispensable basic raw material for organic synthetic chemists to construct novel and specific organic materials and compounds.

The physical properties of 4- (5-iodine-2-methyl-1H-imidazole) depend on its shape, state, point of melting and boiling, as well as solubility and stability.
This compound, under normal conditions, may be solid, and its color may be white to yellowish. Its melting point has a specific value due to intermolecular forces. Due to the interaction of iodine atoms, methyl groups and imidazole rings in the molecular structure, the lattice energy is fixed, so the melting point varies. If heated to the boiling point, it can be vaporized.
Solubility is also an important physical property. In polar solvents, such as water, because the molecule contains a polar imidazole ring, or there is a certain dissolution, then the iodine atom increases the non-polar molecule, resulting in limited solubility. In organic solvents, such as ethanol and dichloromethane, the dissolution is better due to the similar miscibility.
Stability is related to the molecular structure. The imidazole ring is aromatic and stable to a certain extent. However, the iodine atom is active, or the compound reacts under specific conditions. If it encounters a nucleophile, the iodine atom may be replaced and a nucleophilic substitution reaction occurs. Factors such as light and high temperature may also affect its stability and cause decomposition or other chemical changes.
The physical properties of this compound are determined by its molecular structure, and are used in chemical synthesis, drug development, and other fields. Due to these physical properties, there are different applications.

In the synthesis of 4- (5-iodine-2-methyl-1H-imidazole-4-yl) benzoic acid, there are various paths. One is to introduce iodine atoms at a specific position through a halogenation reaction with suitable starting materials. This halogenation method, or using iodine elemental substance and suitable catalyst, under suitable reaction conditions, substitutes are substituted to obtain an intermediate containing iodine.
Next, methyl is introduced into a specific position of the imidazole ring through a methylation reaction. The methylating reagents, such as iodomethane, can be used to achieve this step of conversion under the catalysis of alkali to construct the structure of 2-methyl-5-iodine-1H-imidazole.
Then, through a series of reactions, a benzoic acid group is introduced into a specific position of the imidazole ring. Or by means of nucleophilic substitution, coupling reaction, etc., a suitable reagent containing benzoic acid structure reacts with the resulting imidazole intermediate to obtain the target product 4- (5-iodine-2-methyl-1H-imidazole-4-yl) benzoic acid. In the
reaction, each step requires fine regulation, such as temperature, reaction time, reagent dosage, etc., which are all related to the success or failure of the reaction and the yield. If the temperature is too high or too low during halogenation, side reactions may occur or the reaction rate may be too slow; the strength and dosage of base during methylation also affect the efficiency and selectivity of methylation; the reaction of benzoic acid groups is introduced, and the appropriate coupling method and catalyst are selected to obtain the target product efficiently.

There are 4- (5-iodine-2-methyl-1H-imidazole) of this product today, and the price in the market is geometric, which is difficult to determine. There are many factors that affect its price, and it is difficult to generalize.
Guanfu's "Tiangong Kaiwu", whose book discusses the genus of craftsmanship and products, does not involve the price of this product. And in today's market, the market is fickle, and the trend of supply and demand, the source of origin, the difference in quality, and the difficulty of preparation are all closely related to the price.
If there are many applicants and there are few suppliers, the price will tend to increase; on the contrary, if the supply exceeds the demand, the price may decrease. The origin is far and near, and it also has a relationship. If it is far away, the freight will be imposed on it, and the price will also increase. Those with good quality will always be higher than those with poor quality. It is difficult to prepare, and if you need complicated processes and precious raw materials, the price will be high.
Or you can consult merchants in the market of chemical raw materials, or visit the platform of chemical material trading, to get the approximate price. However, this price is not constant. As time goes on, market conditions change, and the price changes accordingly. Therefore, if you want to know the exact price, you must visit it in real time, and you cannot make assumptions based on old news.

4- (2- (5-iodine-2-methyl-1H-imidazole-1-yl) ethyl) morpholine, which is an important intermediate in the field of fine chemicals, is widely used in medicine, pesticide and other industries. Its storage conditions are crucial, related to the stability and quality of the substance.
This compound should be stored in a cool, dry and well-ventilated place. A cool environment can reduce the probability of chemical reactions caused by excessive temperature. Due to high temperature, molecular activity is often enhanced, or adverse reactions such as decomposition and polymerization are caused. Drying conditions are indispensable, because they may be hygroscopic, or deliquescent or deteriorated after moisture absorption, which affects performance and purity. Good ventilation can disperse volatile gases that may accumulate in time to avoid the formation of flammable and explosive environments.
Furthermore, keep away from fire and heat sources. Both fire and heat sources can cause a sudden rise in temperature and cause dangerous reactions. The storage area should be equipped with suitable fire equipment, just in case. At the same time, it should be stored separately from oxidants, acids, alkalis, etc., because of its active chemical properties, contact with the above substances or react violently.
In addition, storage containers should also be carefully selected. Corrosion-resistant, well-sealed containers should be used to prevent leakage. Regular inspection of the storage area should be carried out to check for signs of leakage and deterioration to ensure safe storage. The quality and stability of 4 - (2 - (5 - iodine - 2 - methyl - 1H - imidazole - 1 - yl) ethyl) morpholine can be effectively guaranteed by following the above storage conditions.