4 5 Imidazoledicarboxylic Acid
quinoline thiophene imidazole thiazole

4,5-Imidazoledicarboxylic acid;

    Specifications

    HS Code

    153022

    Name 4,5-Imidazoledicarboxylic acid
    Chemical Formula C5H4N2O4
    Molar Mass 156.1 g/mol
    Appearance White to off - white powder
    Solubility In Water Soluble in hot water
    Pka1 ~2.3
    Pka2 ~4.9
    Melting Point 295 - 300 °C (decomposes)
    Crystal Structure May form various crystalline forms
    Ph In Solution Acidic, depending on concentration

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    General Information
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    Frequently Asked Questions

    As a leading 4,5-Imidazoledicarboxylic acid; supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4,5-imidazoledicarboxylic acid?
    4,5-diaminodiacetic acid, which is widely used in the fields of medicine and chemical industry.
    In medicine, it is a key raw material for the synthesis of many drugs. For example, the preparation of anti-tumor drugs, 4,5-diaminodiacetic acid has a unique chemical structure, which can precisely bind to specific targets of tumor cells, by blocking the proliferation signal pathway of tumor cells or interfering with their metabolic process, to inhibit the growth and spread of tumor cells. In cardiovascular drug synthesis, it can help build specific active groups and regulate the physiological functions of the cardiovascular system, such as affecting the activity of angiotensin converting enzyme, to stabilize blood pressure and maintain cardiovascular health.
    In the chemical industry, 4,5-diaminodiacetic acid plays a significant role in the synthesis of polymer materials. In the preparation of high-performance engineering plastics, it can be introduced into the polymer chain as a cross-linking agent or comonomer. By polymerizing with other monomers, the material is endowed with excellent mechanical properties, thermal stability and chemical stability. For example, in the preparation of high-end engineering plastics used in the aerospace industry, 4,5-diaminodiacetic acid participates in the construction of a special molecular structure that allows the plastic to maintain excellent performance under extreme temperatures and complex chemical environments, ensuring the reliable operation of aircraft parts. In addition, in the Product Research & Development of coatings, adhesives, etc., it can also optimize product performance, such as improving coating adhesion and durability, and enhancing adhesive strength.
    What are the physical properties of 4,5-imidazoledicarboxylic acid?
    The physical properties of 4,5-diaminodibenzoic acid are quite specific. The color of this substance is white, and it is often shown as a powder, and it is delicate. Its melting point is quite high, about 250 degrees Celsius. At this temperature, it begins to melt into a liquid. This characteristic makes it stable in a solid state in a specific high temperature process to meet the needs.
    In addition, its solubility also has characteristics. In common aqueous solvents, it is difficult to dissolve. The interaction between the polarity of water and the structure of the substance makes it difficult to dissolve in water. However, some organic solvents, such as ethanol and acetone, have certain solubility. The polarity of ethanol and hydrogen bonding can disperse some of the molecules of 4,5-diaminodibenzoic acid. This difference in solubility is very useful in the separation, purification and preparation of related preparations.
    The density of 4,5-diaminodibenzoic acid is also an important physical property. Its density is slightly higher than that of ordinary light organics, about 1.5 grams per cubic centimeter. This density characteristic needs to be carefully considered in the measurement, mixing and design of related reaction systems of materials. Its powder texture, so that its specific surface area is relatively large, when participating in chemical reactions, can provide more reaction check points, so that the reaction is more likely to occur, which in turn is related to the subtle relationship between its physical properties and chemical activity, in the chemical industry, material synthesis and many other fields, are valued by researchers, in order to make good use of its physical properties, for better application results.
    What are the chemical properties of 4,5-imidazoledicarboxylic acid?
    4,5-Diaminodibenzoic acid is one of the organic compounds. It has many unique chemical properties.
    First of all, its physical characteristics, this compound is mostly solid under normal conditions, with a specific melting point and boiling point. The values of its melting point and boiling point can be accurately determined under specific experimental conditions, which is the key index to distinguish its purity and characteristics.
    In terms of chemical activity, in 4,5-diaminodibenzoic acid, the amino group (-NH 2) and the carboxyl group (-COOH) give it significant activity. The amino group is basic and can react with the acid to form the corresponding salt. For example, in the case of hydrochloric acid, amino nitrogen atoms can bind protons to form ammonium salts, and this reaction exhibits its basic characteristics. The carboxyl group is acidic and can neutralize with bases to form carboxylic salts and water. If reacted with sodium hydroxide, the hydrogen atom of the carboxyl group is replaced by sodium ions to form sodium carboxylate salts.
    In addition, the presence of benzene rings in this compound gives it aromatic-related properties. The structure of the benzene ring is stable, but under certain conditions, substitution reactions can also occur. For example, under suitable catalysts and reaction conditions, the hydrogen atom on the benzene ring can be replaced by other atoms or groups, such as halogenation reactions and nitrification reactions. This property is of great significance in the field of organic synthesis, which can be used to prepare a variety of derivatives and expand their application scope.
    Furthermore, the amino group and carboxyl group in 4,5-diaminodibenzoic acid can interact with each other, or can undergo intramolecular or intermolecular condensation reactions. Intramolecular condensation can form a cyclic structure, and intermolecular condensation can form polymers. These reactions are of great value in constructing complex organic molecular structures.
    4,5-diaminodibenzoic acid has rich and diverse chemical properties and has important uses in organic synthesis, pharmaceutical chemistry and other fields, laying a solid foundation for related research and applications.
    What are the synthesis methods of 4,5-imidazoledicarboxylic acid?
    There are several methods for the synthesis of 4,5-dimethylsebacic acid. One method is to start with 2-methyl-1,3-propylene glycol and methyl acrylate. First, 2-methyl-1,3-propylene glycol and p-toluenesulfonic acid are placed in a reactor, heated to 120-130 ° C, dehydrated and condensed to obtain Intermediate A. Next, intermediate A and methyl acrylate are reacted with Michael addition at 60-70 ° C under alkali catalysis to obtain Intermediate B. Intermediate B is then hydrolyzed with potassium hydroxide solution and then acidified to obtain 4,5-dimethylsebacic acid. < Br >
    Another method uses 3-methylglutaric anhydride and ethylene as raw materials. First, 3-methylglutaric anhydride is heated to melt, ethylene is introduced, and an addition reaction is carried out at 150-180 ° C and 3-5 MPa to obtain intermediate C. Subsequently, the intermediate C is reduced and esterified to obtain 4,5-dimethylsebacic acid.
    Another method starts with 4-methyl-1,6-hexanediol and diethyl malonate. Intermediate D was obtained by condensation of 4-methyl-1,6-hexanediol with diethyl malonate at 70-80 ℃ under the catalysis of sodium alcohol. Intermediate D was also obtained by hydrolysis, decarboxylation and other steps. This method has its own advantages and disadvantages, and it needs to be carefully selected according to actual needs, such as the availability of raw materials, cost, yield and other factors.
    What is the price range of 4,5-imidazoledicarboxylic acid in the market?
    4,5-Dimethyladipic acid is on the market, and its price range is difficult to determine. The price of this product often changes due to many reasons, such as the output of the place of origin, the situation of supply and demand, manufacturing costs, competition in the market, and even changes in seasons and regulations.
    In the past, if the place of origin is abundant, the supply exceeds the demand, the price may decline; if the price of raw materials rises, resulting in high manufacturing costs, or a large increase in demand, and the supply is not enough, the price may rise. However, the market situation changes, it is difficult to give a definite price range.
    If you want to know the exact price at this time, you can get the current more accurate price when you carefully consult the chemical product trading platform and consult the manufacturer or distributor. Therefore, if you want to know the market price range of 4,5-dimethyl adipic acid, you should carefully check the real-time information through multiple channels to obtain accurate information, not just based on past or guesswork.