4,5-DICYANO-2-AMINOIMIDAZOLE

4,5-Dihydroxy-2-aminopyrimidine is an organic compound with many unique chemical properties. Its structure contains a pyrimidine ring, an amino group at the 2nd position, and a hydroxyl group at the 4th and 5th positions, which endows it with various chemical activities.
From the theory of acidity and alkalinity, the amino group has a certain alkalinity, and can bind protons under appropriate conditions, showing weak alkalinity; while the hydroxyl group can dissociate protons under certain conditions, showing weak acidity. This amphoteric property allows it to exist in different ion forms in different acid-base environments, affecting its solubility and chemical reactivity.
In terms of solubility, due to the presence of polar amino groups and hydroxyl groups, it can form hydrogen bonds with water molecules, so it has a certain solubility in water and good solubility in polar organic solvents.
In terms of reactivity, amino groups can participate in nucleophilic substitution reactions, such as reacting with halogenated hydrocarbons to form replacement products; hydroxyl groups can undergo esterification reactions and form ester compounds with acids under the action of catalysts. At the same time, due to its conjugation system, the substance can also participate in some electron transfer related reactions, such as oxidation and reduction reactions. In the field of organic synthesis, 4,5-dihydroxy-2-aminopyrimidine is often used as a key intermediate for the synthesis of complex bioactive molecules and drugs, and is an important research object in pharmaceutical chemistry and organic synthesis chemistry.

4,5-Dimethyl-2-hydroxypyrimidine, an important organic compound, has critical uses in many fields.
In the field of medicine, its uses are quite extensive. It is often used as a key intermediate in the synthesis of many drugs. The structural properties of the guyrimidine ring endow it with unique biological activities. By chemically modifying 4,5-dimethyl-2-hydroxypyrimidine, various drugs with specific pharmacological effects can be developed. For example, the preparation of some antibacterial drugs relies on this compound to build a core structure, thereby optimizing its antibacterial properties to effectively inhibit the growth and reproduction of pathogens.
In the field of pesticides, 4,5-dimethyl-2-hydroxypyrimidine also plays an important role. Based on it, a variety of high-efficiency pesticides can be created. Such pesticides can have effects on specific pests or diseases by virtue of their structure and activity characteristics. Or interfere with the physiological and metabolic processes of pests, hinder their growth and development; or inhibit the activities of some key enzymes of pathogens, so as to achieve the purpose of controlling crop diseases and insect pests and ensure crop yield and quality.
In the field of materials science, this compound also shows potential value. In the synthesis of some functional materials, 4,5-dimethyl-2-hydroxypyrimidine can be introduced as a structural unit, giving the material special properties. For example, some materials with optical and electrical properties, through the clever use of this compound, it is expected to improve the performance index of the material and meet the needs of special materials in different fields.
In addition, in organic synthetic chemistry, 4,5-dimethyl-2-hydroxypyrimidine is often used as an important starting material or reaction intermediate. Due to the existence of hydroxyl and methyl groups in its structure, it provides rich possibilities for various chemical reactions, which can be used to construct more complex and diverse organic molecular structures through various reactions such as substitution and addition, and promote the development of organic synthetic chemistry.

4,5-Dihydroxy-2-aminopyrimidine is an important organic compound, and the common synthesis methods are as follows:
** Method using urea and diethyl malonate as starting materials **:
First, urea and diethyl malonate are used under the action of basic catalysts such as sodium ethyl alcohol to carry out a condensation reaction. In this step, the corresponding condensation product can be obtained. The amino group of urea is condensed with the ester group of diethyl malonate to form an intermediate structure containing nitrogen and carbonyl groups. Subsequently, the intermediate product is subjected to a cyclization reaction, and the inner cyclization of the molecule is promoted by adjusting the reaction temperature, pH and other conditions to construct a pyrimidine ring. This process requires fine control of the reaction conditions. If the temperature is too high or too low, and the pH is not suitable, the reaction yield may be reduced or by-products may be formed. After cyclization, an appropriate hydroxylation reaction is carried out to introduce the required hydroxyl groups to achieve the synthesis of 4,5-dihydroxy-2-aminopyrimidine.
* Method of using acetonitrile derivatives as raw materials **:
Select a specific acetonitrile derivative, first react it with a suitable nucleophilic reagent, so that the nitrile group is converted, and the amino group and other related groups are introduced. After that, a series of reactions, such as nucleophilic substitution, addition, etc., gradually build the basic structure of the pyrimidine ring. In this process, the selection and reaction sequence of nucleophiles are extremely critical. Different nucleophiles have different activities. Improper reaction sequence can easily cause the reaction to fail smoothly or generate non-target products. After the initial formation of the pyrimidine ring, hydroxyl groups are introduced through oxidation, hydrolysis and other reactions to complete the synthesis of 4,5-dihydroxy-2-aminopyrimidine.
** Method of using halogenated pyrimidine as raw material **:
Select a suitable halogenated pyrimidine, use it as the starting material, and replace the halogen atom with an amino group through a nucleophilic substitution reaction. The nucleophilic substitution reaction requires the selection of appropriate nucleophilic reagents, such as ammonia or its derivatives, and the influence of reaction solvent, temperature and other factors on the reaction rate and selectivity needs to be considered. Then, other positions on the pyrimidine ring are hydroxylated, and hydroxylation reagents can be used to introduce hydroxyl groups under suitable conditions, and finally 4,5-dihydroxy-2-aminopyrimidine can be synthesized. However, in this way, the selection and purity of halogenated pyrimidine raw materials have a great impact on the quality and yield of the product.

For 4,5-dihydroxy-2-aminopyrimidine, many things must be paid attention to during storage and transportation.
This compound has specific chemical activity and is quite sensitive to environmental conditions. When storing, choose a dry place first. Moisture can easily cause it to hydrolyze or react with other impurities, which can damage quality and purity. Therefore, it should be placed in a dryer or equipped with dehumidification equipment in the storage space to maintain a dry environment.
Temperature is also critical. It should be stored in a cool place to avoid high temperature. High temperature may cause it to decompose, or accelerate the rate of chemical reactions, affecting its stability. Generally speaking, the storage temperature is 2-8 ° C, but the exact temperature depends on the specific nature and requirements.
The choice of storage containers should not be underestimated. Containers with good corrosion resistance and sealing must be used. Glass containers are suitable because of their high chemical stability; if they are aggressive to glass, specific plastic containers should be selected, and the container should be well sealed to prevent contact with air.
When transporting, ensure that the packaging is strong. Wrap with cushioning material to prevent damage to the container due to collision and vibration during transportation. And the transportation environment should also be maintained relatively stable to avoid large fluctuations in temperature and humidity.
Furthermore, due to its possible danger, transportation needs to comply with relevant regulations and safety standards. Transportation personnel should be professionally trained and familiar with emergency treatment measures. In the event of leakage and other situations, they can respond in time to ensure safety.

4,5-Dimethyl-2-hydroxypyrimidine, a class of organic compounds of great importance in the field of medicine and chemical industry. In terms of its market prospects, it can be viewed from the following aspects:
First, in the field of medicine, many drug development uses pyrimidine compounds as the key parent nucleus. 4,5-Dimethyl-2-hydroxypyrimidine, due to its specific chemical structure, can provide the core framework for the development of new antibacterial, antiviral and anti-tumor drugs. With the increasing global attention to health and the continued growth in demand for the treatment of various diseases, this compound is expected to become a popular basic raw material in the development of innovative drugs, and the demand may be on the rise.
It can be used as an intermediate in organic synthesis. With its unique chemical activity, it can participate in the synthesis process of many complex organic compounds, laying the foundation for the preparation of fine chemical products. With the pursuit of high-performance and high-value-added products in the chemical industry, 4,5-dimethyl-2-hydroxypyrimidine, an important intermediate, may play an increasingly critical role in the chemical synthesis route, and the market demand will also expand.
Furthermore, from the perspective of research and development trends, with the advancement of science and technology, new synthesis methods and technologies continue to emerge, which are expected to improve the synthesis efficiency and quality of 4,5-dimethyl-2-hydroxypyrimidine and reduce production costs. The cost reduction will further promote its wide application in various fields, thereby expanding the market scale.
However, it should also be noted that the market competition may become more intense. With its potential value being recognized by more enterprises and scientific research institutions, more companies may participate in the production and research and development of this compound. If enterprises and scientific research teams want to stand out in the market, they must constantly strengthen technological innovation, improve product quality, and optimize cost control.
To sum up, 4,5-dimethyl-2-hydroxypyrimidine has a promising market prospect due to its important use in the fields of medicine and chemical industry, and the cost optimization space brought about by the progress of R & D technology. However, it also faces the challenge of increased competition.