4,5-Dicarboxy-1-methyl-1H-imidazole

4,5-Dicarboxyl-1-methyl-1H-imidazole is widely used in various chemical, pharmaceutical and other industries.
In the chemical industry, it is often the key raw material for organic synthesis. Because of its special chemical structure, it can participate in multiple reactions to prepare other complex organic compounds. If it is combined with other compounds containing active groups through a specific reaction path, it can build a new type of organic framework structure. Such structures are used in the field of materials science or have unique physical and chemical properties, which can be used to develop novel functional materials, such as adsorbents with special adsorption properties, which can be used for environmental purification and have high adsorption and removal ability for specific pollutants; or it can be used to prepare new polymer materials, endowing the materials with unique mechanical properties and stability.
In the pharmaceutical industry, this compound also plays an important role. Due to its similarity in structure with some key substances in organisms, it can be used as a drug intermediate. After chemical modification and modification, a variety of biologically active drugs can be developed. Or it can be designed to fit the pathogenic mechanism of specific diseases. For example, in the research and development of anti-tumor drugs, with its structural characteristics, drugs that can precisely act on tumor cell targets can be constructed to inhibit tumor cell proliferation and induce apoptosis. In the field of anti-infective drugs, drugs that inhibit or kill specific pathogens can also be prepared through rational design to protect human health.
In addition, in biochemical research, 4,5-dicarboxyl-1-methyl-1H-imidazole can be used as a biochemical reagent to explore the chemical reaction mechanism in organisms, helping scientists to deeply understand the mysteries of life processes and contribute to the development of life sciences.

4,5-Dicarboxyl-1-methyl-1H-imidazole This substance is an organic compound. Its physical properties are specific, Rong Laofu will describe it in detail for you.
Looking at its properties, under normal conditions, it may be in a crystalline state, white and pure in color, delicate and uniform in quality. This crystalline substance has a shining light, just like a pearl.
When it comes to the melting point, its melting point is quite clear. When it reaches a certain temperature, it gradually melts from a solid state and turns into a liquid. This temperature is its inherent nature and is one of the characteristics for identifying this substance. The same is true of the boiling point. Under a specific pressure, when heated to a certain temperature, it will boil and dissolve steam. This temperature is also its characteristic.
In terms of solubility, in the solvent of water, there is a certain degree of solubility. Water molecules interact with the imidazole compound molecule, and some molecules can be uniformly dispersed in water, but the amount of solubility is not infinite, which is restricted by many factors such as its molecular structure and the attractive force between water molecules. In organic solvents, such as ethanol and acetone, their solubility varies. In ethanol, it is better to dissolve or dissolve, because the molecular structure of ethanol and 4,5-dicarboxyl-1-methyl-1H-imidazole are in agreement, and they are similar to each other; in acetone, the dissolution may be different, more or less, depending on the strength of the intermolecular force between the two.
Furthermore, the density of this substance is also one of its physical properties. Its density is relatively fixed, and compared with water, it may be heavy or light. This property has important guiding significance in operations such as separation and purification.
In addition, the moisture absorption properties of this substance cannot be ignored. In the environment of high air humidity, it may be able to absorb water vapor, causing its own state to change, or deliquescence, or agglomeration. This requires caution when storing and using.
4,5-dicarboxyl-1-methyl-1H-imidazole has rich and diverse physical properties, such as properties, melting point, solubility, density, hygroscopicity, etc., which are related to each other and together constitute the unique physical properties of this substance. Applications in chemical, pharmaceutical and other fields depend on this.

4,5-Dicarboxyl-1-methyl-1H-imidazole This substance has an acid-base amphoteric. Because it contains a carboxyl group, it can react with bases, and the carboxyl group can give protons, which is acidic; and the nitrogen atom of the imidazole ring, which has lone pairs of electrons, can accept protons, and is basic.
Its solubility is quite special, soluble in water, because its carboxyl group can form hydrogen bonds with water molecules, and it enhances hydrophilicity after ionization; in organic solvents, it varies according to the properties of the solvent. In polar organic solvents, the solubility is good, and in non-polar solvents, it is poor.
In terms of chemical stability, it is relatively stable under normal conditions. When exposed to strong acids and bases, the structure of the carboxyl group and the imidazole ring may change. At high temperatures, it may decompose, triggering structural rearrangement or chemical bond breakage.
Reactive activity is quite high. The carboxyl group can participate in the esterification reaction and form esters with alcohols under the action of catalysts; it can also carry out amidation reaction and form amides with amines. The nitrogen atom of the imidazole ring can be used as a nucleophilic reagent to participate in nucleophilic substitution reactions and combine with electrophilic reagents such as halogenated hydrocarbons.
Because of its special chemical properties, it is often used as a key intermediate in the field of organic synthesis to prepare complex nitrogen-containing heterocyclic compounds; in pharmaceutical chemistry, or because it can interact with specific parts of biological macromolecules, it

The preparation method of 4,5-dicarboxyl-1-methyl-1H-imidazole is not directly mentioned in the classic "Tiangong Kaiwu", but it can be deduced from the relevant process ideas in the book.
In ancient chemical processes, Duoli fire and water methods. To obtain 4,5-dicarboxyl-1-methyl-1H-imidazole, or its related raw materials can be found first. It can be deduced from common substances, or it can be started from natural substances containing imidazole structure, and then hydrolyzed and oxidized.
If a suitable natural substance containing imidazole parent is found, it can be extracted by water method first to dissolve the active ingredients. For example, the method of extracting pigments and drugs in Tiangong Kaiwu uses the power of water to dissolve to separate the required ingredients from impurities. After extraction, the filtrate is evaporated and concentrated to obtain a more concentrated imidazole-containing parent solution.
Then the method of oxidation, although the ancients did not have modern strong oxidants, they could borrow air, weakly oxidizing metal salts, etc. For example, catalyzed by copper salts, it was slowly oxidized in the air to introduce carboxyl groups at specific positions on the imidazole parent. This process requires temperature control and time control to prevent excessive oxidation. For example, in the metallurgical chapter of Tiangong Kaiwu, heat control is about success or failure, and the same is true for this oxidation step.
As for the introduction of methyl groups, alkylation reagents can be used. Although there are no exquisite reagents in ancient times, natural methyl-containing active substances can be found and reacted with imidazole matrix under appropriate conditions. This reaction condition needs to be mild, or can be adjusted moderately by acid and base, so as to promote the reaction to generate 4,5-dicarboxyl-1-methyl-1H-imidazole direction. After the reaction is completed, it is separated and purified. For example, by recrystallization, by the difference in solubility of substances at different temperatures, a pure 4,5-dicarboxyl-1-methyl-1H-imidazole can be obtained. In this way, the preparation method of this compound can be obtained by means of ancient technological ideas.

The price range of 4,5-dicarboxyl-1-methyl-1H-imidazole in the market is difficult to determine. The price often changes due to many reasons, such as the high quality, the situation of supply and demand, the difficulty of preparation, and the fluctuation of market conditions.
If the quality is high, it meets the demand of high specifications, or the cost increases due to the complex preparation process, the price should be high. On the contrary, if the quality is slightly inferior, the preparation is easier, the supply is abundant, and the price may decrease.
And the supply and demand situation has a great impact on the price. If the demand is strong and the supply is limited, the price will rise; if the demand is low, the supply is excessive, and the price may fall.
However, as far as I know, there is no exact public information to specify the price range. To know the details, or to consult the merchants specializing in such chemicals, or to check the latest market conditions of chemical products trading platforms, you can get a more accurate price. Because the chemical market is constantly changing, prices often vary from time to time, so in order to obtain accurate prices, real-time research is essential.