4 1 2 3 Dimethylphenyl Ethyl 1h Imidazole Hydrochloride
quinoline thiophene imidazole thiazole

4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride

    • Product Name 4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride
    • Alias Clotrimazole hydrochloride
    • Einecs 66391-51-3
    • Mininmum Order 1 g
    • Factory Site West Ujimqin Banner, Xilingol League, Inner Mongolia, China
    • Price Inquiry sales9@alchemist-chem.com
    • Manufacturer Taiy Chemical
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    Specifications

    HS Code

    811399

    Chemical Name 4-[1-(2,3 - dimethylphenyl)ethyl]-1h-imidazole hydrochloride

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    Frequently Asked Questions

    As a leading 4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4- [1- (2,3-dimethylphenyl) ethyl] -1H-imidazole hydrochloride?
    4- [1- (2,3-dimethylbenzyl) ethyl] -1H-indole-2-carboxylic anhydrides are organic compounds with complex chemical properties and diverse properties.
    In this compound, the core structure of 1H-indole ring is rich in electrons, so it exhibits certain aromaticity and can undergo typical aromatic reactions such as electrophilic substitution reactions. For example, under appropriate conditions, it can be substituted with halogenated hydrocarbons at specific positions of the indole ring to form halogenated derivatives. This is because the electron cloud distribution of the indole ring makes some check points highly reactive to electrophilic reagents.
    Furthermore, 2-carboxylic anhydride is partially active and easy to hydrolyze in contact with water to form corresponding carboxylic acids. In an alkaline environment, the hydrolysis rate is faster and will be rapidly converted into carboxylic salts. The hydrolyzed carboxylic acid can further esterify with alcohols under the action of a catalyst to form ester compounds, which provides a path for the preparation of specific ester derivatives.
    In addition, the carbon chain structure of the 4 - [1 - (2,3 - dimethylbenzyl) ethyl] part has an impact on the physical properties of the compound. Longer carbon chains increase intermolecular van der Waals forces, resulting in relatively high melting points and boiling points, and their solubility in organic solvents is different from that of small molecule compounds. At the same time, the presence of benzyl and dimethyl affects the molecular steric resistance and has an effect on the selectivity of the reaction. For example, in the electrophilic substitution reaction, the steric resistance will limit the attack direction of the reagent, so that the reaction mainly occurs in the area with small steric resistance.
    From this perspective, the chemical properties of 4- [1- (2,3-dimethylbenzyl) ethyl] -1H-indole-2-carboxylic anhydride are determined by the synergistic structure of its various parts. In the field of organic synthesis, a variety of organic compounds with specific functions can be designed and synthesized by virtue of their characteristics.
    What are the uses of 4- [1- (2,3-dimethylphenyl) ethyl] -1H-imidazole hydrochloride?
    4- [1- (2,3-dimethylbenzyl) ethyl] -1H-indole-2-carboxylic anhydride has a wide range of uses. In the field of medicine, it can be used as a key intermediate to synthesize compounds with specific biological activities. For example, in the development of some new anti-tumor drugs, this substance can be cleverly connected with other active groups through a series of chemical reactions to construct molecular structures with targeted inhibitory functions on tumor cells, providing a strong material basis for the treatment of tumor diseases.
    In the field of materials science, it can be used to prepare materials with special photoelectric properties. Due to its unique electronic conjugate system with a molecular structure, it can be applied to photoelectric devices such as organic Light Emitting Diodes (OLEDs) or solar cells after appropriate modification and processing, thereby improving the luminous efficiency or photoelectric conversion efficiency of the device and promoting the development of materials science.
    In the field of organic synthesis chemistry, 4- [1- (2,3-dimethylbenzyl) ethyl] -1H-indole-2-carboxylic anhydride, as a multifunctional synthetic building block, can use a variety of organic reactions, such as nucleophilic substitution, cyclization reactions, etc., to construct complex and diverse organic compounds, greatly enriching the paths and product types of organic synthesis, injecting new vitality into the development of organic chemistry.
    What is the synthesis method of 4- [1- (2,3-dimethylphenyl) ethyl] -1H-imidazole hydrochloride?
    To prepare 4- [1 - (2,3 - dimethylbenzyl) ethyl] -1H - indole - 2 - carboxylic anhydride, the method is as follows:
    First take an appropriate amount of 2,3 - dimethyl benzyl halide, and a reagent containing an active group of ethyl, in a suitable solvent, followed by a matching base, temperature control and stirring, so that nucleophilic substitution reaction, to obtain 1 - (2,3 - dimethylbenzyl) ethane intermediate. After the reaction, the intermediate is refined by conventional separation and purification methods, such as extraction, distillation, recrystallization, etc. < Br >
    After this purification, the intermediate of 1- (2,3-dimethylbenzyl) ethane, together with the indole-2-carboxylic acid derivative, is added to a specific organic solvent with a suitable catalyst to promote the condensation reaction at a certain temperature and reaction time. This process requires fine regulation of the reaction conditions to increase the yield of the target product.
    After the condensation reaction is completed, the reaction system is cooled, and the crude product is precipitated with a specific precipitant or separation method. After several washing, recrystallization and other purification steps, a pure 4- [1- (2,3-dimethylbenzyl) ethyl] -1H-indole-2-carboxylic acid is obtained.
    Finally, the carboxylic acid product is dehydrated to anhydride at a suitable temperature and reaction environment with an appropriate amount of dehydrating agent, such as acetic anhydride or phosphorus pentoxide. At the end of the reaction, the product was separated and purified by reduced pressure distillation, column chromatography, etc., to obtain 4- [1 - (2,3 - dimethylbenzyl) ethyl] -1H - indole - 2 - carboxylic anhydride. Throughout the synthesis process, each step needs to strictly control the reaction conditions, pay attention to the purity of raw materials, dosage, reaction time, temperature, pH and other factors to ensure the smooth progress of synthesis and the quality of the product.
    What Are the Quality Standards for 4- [1- (2,3-Dimethylphenyl) Ethyl] -1H-Imidazole Hydrochloride
    4 - [1 - (2,3 - dimethylbenzyl) ethyl] - 1H - indole - 2 - carboxylic acid quality standards, although not directly described in "Tiangong Kaiwu" for this specific compound standard, but it contains a lot of ancient wisdom on material quality control, which can be used for reference.
    The ancients were in things, and the heavy materials were excellent. In order to obtain high quality of this compound, the selection of raw materials should be the first priority. As "Tiangong Kaiwu" said, all the processes are heavy on the advantages of starting materials. 2,3 - dimethylbenzyl and related raw materials need to be selected with pure texture and no impurities, which is the quality foundation. If impurities exist, they will be in the reaction process or obstructed, resulting in impure products.
    The reaction operation is also about quality. The ancient people's workmanship paid attention to the heat and precise time. In the preparation of this compound, the reaction temperature and time must be strictly controlled. If the temperature is too high or too low, the reaction can be biased, the product may not be available, or there are too many by-products. Improper time, the reaction may not be complete, or the reaction may be overreacted, which will damage the quality of the product.
    Purification steps should also not be ignored. "Tiangong Kaiwu" records many purification methods, such as gushing, steaming, etc. This compound also needs to be suitable for purification to remove impurities and keep pure products. If the purification is not good, impurities will remain in the product, which will affect its quality and use.
    The properties of the product are also the key to quality. When checking its color, shape, etc. If the appearance of all kinds of products is described in the book, this compound should have a specific color and shape. If it is different from this, the quality may be poor.
    Content determination is also necessary. When an appropriate method is used to confirm that the content of 4- [1- (2,3-dimethylbenzyl) ethyl] -1H-indole-2-carboxylic acid in the product meets the standard, it is a qualified product.
    What is the market price of 4- [1- (2,3-dimethylphenyl) ethyl] -1H-imidazole hydrochloride?
    The market value of 4- [1- (2,3-dimethylbenzyl) ethyl] -1H-indole-2-carboxylic acid is difficult to determine. The price of the compound is not constant and is influenced by various factors.
    First, the source and cost of the material are also. If the raw material for the preparation of this compound is easy to obtain and the price is flat, the production price may also be lower; conversely, if the raw material is rare and difficult to find, the price of this compound will be high.
    Second, the complexity and simplicity of the process are crucial. If the preparation method is simple, requires less manpower, material resources, and financial resources, the price will also be lower; if the production process is complicated, requires many steps, and each step needs to be carefully controlled, and the equipment and reagents used are also exquisite, the cost will increase and the price will be high.
    Third, the supply and demand of the city is also due to this. If the city has a strong demand for this product, but the supply is small, the price will increase; if the demand is small and the supply is large, the price will be reduced.
    Fourth, the price may vary depending on the region. Due to differences in taxes, freight, and market conditions in various places, the price of the same compound may be different from that in other places.
    To determine the market price, it is necessary to review the fluctuation of raw material prices, changes in manufacturing, dynamics of supply and demand, and regional differences. Or to observe the market conditions of chemical transactions in detail, consult business experts, experts, or refer to professional market survey reports to obtain a more accurate price.