What is the chemical structure of (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3,4-d] imidazole-4-pentanoic acid 2,3,4,5,6-pentafluorophenyl ester

This is the chemical structure analysis of (3aS, 4S, 6aR) -hexahydro-2-oxo-1H-thiopheno [3,4-d] imidazole-4-pentanoic acid 2,3,4,5,6-pentafluorobenzene ester. Its structure consists of a thiophene imidazole ring system, which is formed by fusing the thiophene ring with the imidazole ring. It is located in a specific position in the ring, that is, at the 3a, 4, and 6a positions, and has a specific stereo configuration, which is the S, S, and R configuration, respectively.

Furthermore, the hexahydro structure implies that this ring system undergoes a hydrogenation process, and some double bonds are saturated. 2-oxygen indicates the presence of a carbonyl group at the 2 position on the ring. The valeric acid part adds a pentacarbon chain to the molecule, and the chain end is a carboxyl group. This carboxyl group is partially connected to 2,3,4,5,6-pentafluorophenyl ester to form an ester bond.

This chemical structure endows the compound with unique physical and chemical properties due to the specific ring system, stereo configuration and combination of substituents, and may have specific application value in organic synthesis, medicinal chemistry and other fields.

What are the physical properties of (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3,4-d] imidazole-4-pentanoic acid 2,3,4,5,6-pentafluorophenyl ester

(3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3,4-d] imidazole-4-pentanoic acid 2,3,4,5,6-pentafluorophenyl ester is an organic compound. Its physical properties are quite important and are related to many properties of this compound.

Looking at its morphology, it is often in a solid state, and it has good stability under conventional environmental conditions. Its melting point is an important indicator. The temperature at which the compound transitions from solid to liquid can be determined experimentally. This temperature data is of great significance for its subsequent processing and application. For example, if it is used in a specific chemical reaction, it is necessary to know the melting point to precisely control the reaction temperature range to ensure the smooth progress of the reaction.

In terms of solubility, it varies in organic solvents. In some polar organic solvents, such as dichloromethane, N, N-dimethylformamide, it exhibits a certain solubility. This property makes it widely used in the field of organic synthesis, making it easy to participate in various chemical reactions in solution systems, which is conducive to the full mixing of reactants and promotes the reaction process. However, the solubility in water is poor, because the hydrophobic part of the molecular structure accounts for a large proportion, resulting in weak interaction with water molecules.

The density of this compound is also a key physical property. Density data can provide a basis for its storage, transportation and practical application. In industrial production, knowing the density can accurately calculate its loading capacity in a specific volume container, avoiding safety problems or affecting production efficiency due to overloading or underloading.

In addition, its appearance color is also intuitive physical properties. In pure state, it may appear white to white powder shape, which helps to preliminarily judge its purity and quality during experiments and production processes. If the color changes significantly, it may suggest that the compound has impurities or chemical changes.

In summary, the physical properties of (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3,4-d] imidazole-4-pentanoic acid 2,3,4,5,6-pentafluorophenyl ester, from morphology, melting point, solubility, density to appearance color, etc., together constitute its unique physical properties, laying the foundation for its application in scientific research, industry and other fields.

What are the chemical properties of (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3,4-d] imidazole-4-pentanoic acid 2,3,4,5,6-pentafluorophenyl ester

(3aS, 4S, 6aR) -hexahydro-2-oxo-1H-thiopheno [3,4-d] imidazole-4-pentafluorobenzene pentafluoroate, this is an organic compound. Its chemical properties are unique and have specific physical and chemical characteristics.

Looking at its structure, this compound contains thiopheno-imidazole ring, and is connected with pentafluorophenyl group and pentafluorophenyl group. The existence of thiopheno-imidazole ring endows it with certain stability and special reactivity. The sulfur atom and nitrogen atom in the ring can participate in a variety of chemical reactions, such as nucleophilic substitution, oxidation reduction, etc. Because nitrogen and sulfur atoms have lone pairs of electrons, they can react with electrophilic reagents to form new chemical bonds. The introduction of the

valerate ester group affects the solubility and steric resistance of the compound. The ester group can undergo hydrolysis reaction, and under the catalysis of acid or base, the corresponding acid and alcohol are generated. This hydrolysis property may enable the compound to participate in the reaction process of esterification-hydrolysis equilibrium under specific conditions. The existence of the

pentafluorophenyl group greatly affects the electron cloud distribution and hydrophobicity of the compound. The fluorine atom has strong electronegativity and a significant electron-absorbing effect, which reduces the electron cloud density of the benzene ring. This electronic effect may affect the interaction between the compound and other molecules, such as the reactivity with nucleophiles or electrophilic reagents. At the same time, the high hydrophobicity of pentafluorophenyl affects the solubility and partitioning behavior of the compound in different solvents.

In addition, the stereochemical structure of the compound, namely the (3aS, 4S, 6aR) configuration, also has an important impact on its chemical properties and biological activities. Compounds with different stereoconfigurations may exhibit very different chemical reactions in vivo, or affect their ability to bind and selectivity to biological targets.

What is the main use of (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3,4-d] imidazole-4-pentanoic acid 2,3,4,5,6-pentafluorophenyl ester

(3aS, 4S, 6aR) -hexahydro-2-oxo-1H-thiopheno [3,4-d] imidazole-4-valeric acid 2,3,4,5,6-pentafluorophenyl ester, this compound has unique uses in many fields.

In the field of pharmaceutical chemistry, or as a key intermediate for the delicate creation of drugs. The special thiopheno-imidazole ring in its structure, combined with pentafluorophenyl ester, endows the molecule with specific physical and chemical properties, or can precisely fit with specific targets in organisms, just like the correspondence between a key and a lock. Based on this, medical scientists can use ingenious modifications and modifications to carefully develop specific drugs for specific diseases, such as targeted anti-cancer drugs, which can precisely target cancer cells, but do little damage to normal cells, contributing to the solution of cancer problems.

In the field of organic synthesis, it is a precious cornerstone for building complex organic molecules. Because of its unique structure, it can be skillfully spliced with other organic fragments through various chemical reactions, such as esterification, substitution, etc., such as the ability of craftsmen to splice delicate components to build complex and functional organic macromolecules, opening up new paths for materials science, natural product synthesis and other fields, and promoting the birth of new functional materials.

In chemical biology research, molecules can be used as powerful tools. With their specific interactions with biomolecules, scientists can deeply explore complex biochemical processes in organisms, such as protein-protein interactions, enzyme catalysis mechanisms, etc., providing key information for revealing the mysteries of life.

What are the synthesis methods of (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3,4-d] imidazole-4-pentanoic acid 2,3,4,5,6-pentafluorophenyl ester

The synthesis of (3aS, 4S, 6aR) -hexahydro-2-oxo-1H-thiopheno [3,4-d] imidazole-4-pentafluorobenzene ester is the key to organic synthesis. The synthesis of this compound can follow several paths.

The first path is to build the core thiopheno-imidazole ring structure through a multi-step reaction, and then introduce the side chain of pentanoic acid, and finally esterify with 2,3,4,5,6-pentafluorophenol. The starting material is selected from compounds containing sulfur and nitrogen, and the thiopheno-imidazole ring is constructed through a condensation reaction. This step requires fine regulation of reaction conditions, such as temperature, pH and reaction time, to ensure the smooth progress of cyclization. Subsequently, the valeric acid group is introduced at a suitable check point, or achieved by nucleophilic substitution. Finally, under the catalysis of acid or base, the valeric acid derivative is esterified with 2,3,4,5,6-pentafluorophenol to obtain the target product.

Another route is to synthesize the thiophenimidazole precursor containing the side chain of valeric acid first, and then couple it with the 2,3,4,5,6-pentafluorobenzene fragment. In this case, when synthesizing the thiophenimidazole precursor, the reaction efficiency and selectivity can be optimized by modifying the structure and reaction sequence of the reactants. The coupling step requires selecting suitable coupling reagents and catalysts to improve the reaction yield and product purity.

During the synthesis process, every step of the reaction needs to be carefully monitored and purified, and the purity of the intermediate and final products should be ensured by means such as thin-layer chromatography and column chromatography. The atomic economy and environmental friendliness of the reaction should also be considered, and the synthesis method should be green and efficient. In this way, after many considerations and practices, a good synthesis method suitable for this compound can be found.