3-(N-phenyl-2-benzimidazole)phenylboronic acid

3- (N-phenyl-2-benzimidazole) phenylboronic acid, an organoboron compound, has important applications in many fields.
In the field of organic synthesis, it often acts as a key intermediate. With the unique reactivity of carbon-boron bonds, Suzuki-Miyaura coupling reactions can be used to combine halogenated aromatics or halogenated olefins to form carbon-carbon bonds, synthesizing complex organic molecules with specific structures, which are widely used in the synthesis of drugs, natural products and functional materials. For example, in drug development, molecular frameworks with specific biological activities can be synthesized by this method, laying the foundation for the creation of new drugs. < Br >
In the field of materials science, it also has outstanding performance. It can be used as a building unit to prepare organic materials with special optoelectronic properties. Due to its strong structural modifiability, it can change the electrical and optical properties of materials by adjusting the substituents, such as the preparation of Light Emitting Diode (LED) materials, organic solar cell materials, etc. Like some materials containing the boric acid structure, it exhibits excellent fluorescence properties and has great potential in the fabrication of optoelectronic devices.
In the field of chemical sensing, it also plays an important role. Due to the affinity of boron atoms to specific molecules or ions, sensors with selective recognition capabilities for certain substances can be designed. For example, for carbohydrate molecules, the property of forming reversible covalent bonds with boric acid can be used to develop sensors for detecting the concentration of carbohydrates, which is of great significance in biomedical detection and food analysis.
In summary, 3- (N-phenyl-2-benzimidazole) phenylboronic acid is widely used in organic synthesis, materials science and chemical sensing, and is of great significance to promote the development of related fields.

To prepare 3- (N-phenyl-2-benzimidazole) phenylboronic acid, the following method can be followed.
First take N-phenyl-2-benzimidazole as the base material, and combine it with the halogen containing the benzene ring under appropriate reaction conditions. This process requires careful selection of catalyst and reaction solvent so that the two can effectively combine to form 3- (N-phenyl-2-benzimidazole) phenyl halide.
Then, the prepared 3- (N-phenyl-2-benzimidazole) phenyl halide is reacted with a metal reagent, such as an organolithium reagent or a Grignard reagent. This reaction can replace the halogen atom with a metal atom to form a corresponding metal-organic compound.
Next, the metal-organic compound is reacted with a borate ester reagent, such as trimethoxyborate or triisopropoxyborate, under appropriate conditions. After the reaction is completed, the borate ester can be hydrolyzed into boric acid through a hydrolysis step, and the final product is 3- (N-phenyl-2-benzimidazole) phenylboronic acid.
During the whole process, the control of reaction conditions is crucial, such as temperature, reaction time, and the proportion of reactants, which all affect the yield and purity of the product. It needs to be optimized by many tests to find the best reaction conditions to achieve efficient and high-purity synthesis.

3- (N-phenyl-2-benzimidazole) phenylboronic acid, this is an organoboron compound with unique physical and chemical properties.
Its appearance, under normal conditions or white to light yellow crystalline powder, fine texture. Due to the molecular structure containing benzimidazole and phenylboronic acid groups, it is endowed with certain stability and special chemical activity.
In terms of melting point, it is about [X] ° C, and the specific melting point will vary due to impurities or crystal forms. This property is crucial for the identification and purification of this compound, and its purity can be judged by melting point measurement. < Br >
Solubility, slightly soluble in water, due to the large proportion of organic groups in the molecule, it is hydrophobic. However, it can be soluble in common organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. The solubility in different solvents is conducive to its operation as a reactant or intermediate in organic synthesis reactions. It can choose a suitable solvent according to the reaction requirements to improve the reaction efficiency and selectivity.
Good thermal stability, and can maintain structural and chemical stability within a specific temperature range. However, at high temperatures, decomposition reactions may occur, causing molecular structure changes and releasing decomposition products containing boron, nitrogen, etc. Therefore, it is necessary to control the temperature during storage and use to avoid high temperature decomposition.
In acidity, it has a certain acidity due to the presence of boric acid groups. In aqueous solution, boric acid groups can be weakly ionized and release protons, but their acidity is weaker than that of common inorganic acids. This acidic property makes this compound play a special role in some acid-base catalytic reactions, and can be used as a mild acid catalyst or participate in acid-base equilibrium related reactions.
3- (N-phenyl-2-benzimidazole) phenylboronic acid has rich physical and chemical properties, which lay the foundation for its application in organic synthesis, materials science and other fields.

I don't know the price range of 3- (N-phenyl-2-benzimidazole) phenylboronic acid in the market. The price of this chemical substance often varies due to many reasons. If the preparation is difficult, the price of the raw materials used, and the amount of demand can affect its price.
If the preparation of this boric acid requires complex processes and rare raw materials, its price must be high; on the contrary, if the preparation is easier and the raw materials are common, the price may be low. And when the market demand is large, the price may rise; when the demand is small, the price may be depressed.
And the price set by different merchants also varies, due to the different calculations of costs and profits of each merchant. Some merchants may sell it at a low price in order to occupy the market; some merchants price it slightly higher due to excellent quality and service.
To know the exact price, you should carefully investigate the chemical raw material market and consult multiple suppliers to compare their quotations before you can get a more accurate price range.

The stability of 3- (N-phenyl-2-benzimidazole) phenylboronic acid is related to many aspects. The structural characteristics of this compound have a great influence on its stability. In its molecule, benzimidazole and phenylboronic acid are partially connected to each other to form a specific spatial configuration and electron distribution.
From the perspective of chemical bonds, the covalent bond between benzimidazole and phenyl group, if the bond energy is quite high, the structure is relatively stable. Although the boron-oxygen bond in phenylboronic acid has a certain polarity, if the surrounding atoms or groups can provide electron cloud stabilization, it can also enhance the overall stability.
Furthermore, external environmental factors cannot be ignored. When the temperature rises, the thermal motion of the molecule intensifies, or the vibration of the chemical bond is enhanced, which may loosen the molecular structure and reduce the stability. In humid environments, water molecules may interact with boric acid groups, such as forming hydrogen bonds, or changing the intermolecular forces, which in turn affect the stability.
In organic solvents, the interaction between the solvent and the compound also affects its stability. If the solvent and the intermolecular force are appropriate, the molecular structure can be stabilized; conversely, if the force is too strong or too weak, it may cause molecular structure changes.
In terms of chemical reactivity, this compound has certain reactivity due to its boric acid group. If there are substances in the environment that are easy to react with, such as nucleophiles, etc., or a chemical reaction occurs, the structure of the original compound changes and the stability is naturally damaged.
In summary, the stability of 3- (N-phenyl-2-benzimidazole) phenylboronic acid is not only affected by its own structural characteristics, but also by external factors such as temperature, humidity, solvent and chemical reaction environment. All factors must be considered comprehensively to fully grasp its stability.