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What is the chemical structure of 2- [ (RS) - [ (3,5-dimethylpyridin-2-yl) methyl] sulfinyl] -5-methoxy-1H-benzimidazole?
I think this is a question about the structure of organic compounds. This compound has a variety of names and contains many groups. Its core structure may be 1H-indolopyridine, with a variety of groups modified on the side.
2- [ (RS ) - [ ( 3,5-dimethylbenzyl-2-yl) benzyl] sulfinyl] -5 -methoxy-1H-indolopyridine, 1H-indolopyridine is the key structure, which is a fused ring system with nitrogen heterocycles, which is common in many drugs and bioactive molecules. < Br >
At position 2, it is connected with (RS ) - [ ( 3,5-dimethylbenzyl-2-yl) benzyl] sulfinyl group. This group is complex, (RS) is chiral, or there are two enantiomers. (3,5-dimethylbenzyl-2-yl) benzyl is derived from the benzene ring and has dimethyl modification. It is connected to the main structure with a sulfinyl group. The sulfur atom in the sulfinyl group is connected to an oxygen atom and a hydrocarbon group, or affects molecular polarity and reactivity.
5 position is connected to methoxy, and methoxy is used as the power supply group, which can change the electron cloud density of the indolopyridine ring, and affect the electrophilic substitution reaction activity and molecular physical properties.
In summary, this compound has a complex structure, and each group affects each other. Its unique structure may endow special chemical and biological activities, which may have potential value in drug development, organic synthesis and other fields.
What are the main pharmacological effects of 2- [ (RS) - [ (3,5-dimethylpyridin-2-yl) methyl] sulfinyl] -5-methoxy-1H-benzimidazole?
2-%5B%28RS%29-%5B%283%2C5- dimethylbenzyl-2-yl% 29methyl% 5D salicylic% 5D-5-methoxy-1H-indole compounds have a variety of important pharmacological effects.
In the nervous system, it can regulate the release and transmission of neurotransmitters. For example, it has a certain ability to regulate the secretion of neurotransmitters such as dopamine and serotonin, which has potential effects on relieving symptoms of psychiatric diseases such as anxiety and depression. In some studies, it has been found that these compounds can affect the signal transduction pathways of nerve cells, repair damaged nerve cell connections, thereby improving cognitive function, or can be used to treat neurodegenerative diseases such as Alzheimer's disease.
In the field of cardiovascular system, it can act on vascular smooth muscle cells and regulate the contraction and relaxation of blood vessels. By affecting mechanisms such as calcium ion channels, blood vessels maintain proper tension, which helps to maintain normal blood pressure levels and has positive significance for the treatment of cardiovascular diseases such as hypertension. At the same time, it can also inhibit the aggregation of platelets, reduce blood viscosity, reduce the risk of thrombosis, and prevent cardiovascular blockage and other diseases.
In addition, these compounds have outstanding anti-inflammatory properties. They can inhibit the production and release of inflammatory mediators, such as inhibiting the activity of inflammatory factors such as interleukin and tumor necrosis factor, and reduce the damage of inflammatory reactions to tissues and organs. They have potential therapeutic value for inflammatory diseases such as arthritis and enteritis.
It has also emerged in the anti-tumor field, which can induce tumor cell apoptosis and inhibit the proliferation and metastasis of tumor cells. By acting on the signaling pathway of tumor cells, it blocks the growth and diffusion signaling of tumor cells, providing new ideas and potential drug options for tumor treatment.
What are the clinical application scenarios of 2- [ (RS) - [ (3,5-dimethylpyridin-2-yl) methyl] sulfinyl] -5-methoxy-1H-benzimidazole?
2-%5B%28RS%29-%5B%283%2C5- dimethylbenzyl-2-yl% 29methyl% 5D salicylic% 5D-5-methoxy-1H-indole such compounds have specific application scenarios in many fields.
In the field of pharmaceutical research and development, due to its unique chemical structure, or have biological activity. For example, in the study of anti-tumor drugs, some indole-containing compounds can act on specific targets of tumor cells, affecting tumor cell proliferation and apoptosis-related signaling pathways. Special substituents in this compound, such as 3,5-dimethylbenzyl-2-yl and salicylidene, may endow them with unique pharmacological activities, providing direction for the development of new anti-tumor drugs. < Br >
In the field of materials science, it may exhibit optical and electrical properties. For example, some indole-containing derivatives can be used to prepare organic Light Emitting Diode (OLED) materials, which can achieve high-efficiency luminescence by virtue of their structural characteristics. The specific substituent of this compound may affect its electron cloud distribution and energy level structure, improve the luminous efficiency and stability of the material, and have potential application value in the field of display technology.
In the field of agriculture, it may become the basis for the creation of new pesticides. Some indole-containing compounds have inhibitory or killing effects on pests and diseases. The structural properties of this compound may make it have a control effect on specific crop diseases and pests, and the development environment is friendly, efficient and low-toxicity new pesticides.
What are the side effects of 2- [ (RS) - [ (3,5-dimethylpyridin-2-yl) methyl] sulfinyl] -5-methoxy-1H-benzimidazole?
2 - [ (RS) - [ (3,5-dibenzylallyl-2-yl) benzyl] salicylic] - 5-benzyloxy-1H-indolocarbazole has many properties that are of great significance in the fields of medicine and materials.
In the field of medicine, one of them may affect cell signaling pathways. The structural characteristics of the substance may bind to specific receptors or signaling molecules in the cell, like a key inserted into a keyhole, which may interfere with the normal signaling process. For example, in the cell proliferation and differentiation signaling pathway, its interference may cause uncontrolled cell growth, which may lead to diseases such as tumors. Second, it may also have an impact on the nervous system. It may interact with neurotransmitter receptors through the blood-brain barrier, thereby interfering with the normal transmission of neurotransmitters, resulting in adverse neurological reactions such as dizziness, headache, insomnia and even mental disorders.
In the field of materials, on the one hand, during the preparation of materials, it may affect the crystallization behavior of materials. Due to its complex structure, it may interfere with the growth and arrangement of crystals as an impurity, resulting in changes in the crystallinity of materials, which in turn affect the mechanical properties and thermal properties of materials. On the other hand, in the application environment of materials, this substance may chemically react with surrounding media. For example, in a humid environment, some of its functional groups may hydrolyze or form hydrogen bonds with water molecules, which not only alters the chemical composition of the material, but also may cause material properties to deteriorate, such as unstable electrical and optical properties of the material.
What is the metabolic process of 2- [ (RS) - [ (3,5-dimethylpyridin-2-yl) methyl] sulfinyl] -5-methoxy-1H-benzimidazole in vivo?
The metabolic process of fudemin 2 - [ (RS) - [ (3,5-dimethylbenzyl-2-yl) methyl] sulfoxyl] -5 -methoxy-1H-indole in vivo requires detailed investigation of its reaction mechanism and pathway.
The structure of this compound is slightly complex, and the key structural parts such as [ (3,5-dimethylbenzyl-2-yl) methyl] sulfoxyl are susceptible to the action of enzymes in vivo due to the characteristics of sulfur atoms contained in it. Many enzymes in the body, such as cytochrome P450 enzymes, often participate in the metabolic transformation of foreign compounds. The methoxy part of it may be separated from the methoxy group and converted into hydroxyl groups by the action of related methyltransferases through demethylation reaction, which is a common metabolic pathway.
For the indole ring structure, oxidation reaction may also occur. Under the catalysis of enzymes, oxygen atoms are introduced into specific positions of the indole ring to form products such as hydroxyindole. Furthermore, the stereochemical characteristics represented by the (RS) configuration may also affect its metabolic process. Different configurations or affinities with enzymes are different, resulting in differences in metabolic rate and product ratio.
In addition, the metabolic environment in the body is complex and changeable, and acid-base conditions, various coenzymes and cofactors can all affect the metabolism of the compound. In different tissues and organs, the metabolic pathways may vary due to the different enzyme expression profiles. As the main metabolic organ, the liver is rich in a variety of enzymes involved in the metabolism of foreign substances. The compound may undergo more complex reactions such as oxidation, reduction, hydrolysis and binding to generate a variety of metabolites, which are then excreted in urine or bile.