2 R 3 Methyl 4 2 2 2 Trifluoroethoxy 2 Pyridinyl Methyl Sulfinyl 1h Benzimidazole
quinoline thiophene imidazole thiazole

2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole

    Specifications

    HS Code

    758070

    Chemical Name 2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
    Molecular Formula C17H16F3N3O2S
    Molecular Weight 383.39
    Appearance Typically a solid (physical appearance may vary based on purity and conditions)
    Melting Point Varies, data may be specific to the pure compound under standard conditions
    Solubility Solubility characteristics depend on the solvent; may have limited solubility in water but better solubility in organic solvents
    Pka Specific pKa values related to acidic or basic groups in the molecule would be determined by experimental methods
    Logp Value indicating lipophilicity, relevant for understanding its distribution between lipid and aqueous phases
    Stability Stability can be affected by factors like temperature, light, and humidity
    Reactivity Reactivity towards various chemical reagents would depend on the functional groups present

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    Frequently Asked Questions

    As a leading 2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2- [ (R) - [3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] sulfinyl] -1H-benzimidazole?
    This is the structural description of an organic compound. To understand its details, it needs to be analyzed step by step according to the system nomenclature.
    First view "2 - [ (R ) - [ [ 3-methyl-4 - (2,2,2-trifluoroethoxy) - 2-allyl] methyl] salicylic] -1H-indole". "1H-indole" is the parent nucleus, which is like the cornerstone of a building. It has a specific cyclic structure and is formed by fusing a benzene ring with a five-membered nitrogen-containing heterocycle.
    "2 - [ (R ) - [ [ 3-methyl-4- (2,2,2-trifluoroethoxy) - 2-allyl] methyl] salicylic]" This part is a substituent, connected to the 2 position of indole. The configuration of the " (R) " chiral center has a specific spatial orientation.
    "[[3-methyl-4- (2,2,2-trifluoroethoxy) - 2-allyl] methyl]" is a complex substituent. " 3-Methyl "indicates a methyl substitution at the 3rd position of the main chain;" 4- (2,2,2-trifluoroethoxy) "indicates a 2,2,2-trifluoroethoxy group at the 4th position, which contains three fluorine atoms and has special electronic effects;" 2-allyl "refers to an allyl group at the 2nd position, which is reactive.
    " Salicylic "is also one of the substituents, connected to the above complex substituents, and then connected to the indole 2 position. It has unique structural and electronic properties, which affect the overall properties of the compound.
    Overall, the complex structure of this compound and the interaction of various substituents endow it with unique physical and chemical properties, which may have potential application value in the fields of organic synthesis and drug development.
    What are the main physical properties of 2- [ (R) - [3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] sulfinyl] -1H-benzimidazole?
    2-%5B%28R%29-%5B%5B3-%E7%94%B2%E5%9F%BA-4-%282%2C2%2C2-%E4%B8%89%E6%B0%9F%E4%B9%99%E6%B0%A7%E5%9F%BA%29-2-%E5%90%A1%E5%95%B6%E5%9F%BA%5D%E7%94%B2%E5%9F%BA%5D%E4%BA%9A%E7%A3%BA%E9%85%B0%E5%9F%BA%5D-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91 is a complex organic compound, this substance has some important physical properties.
    In terms of its appearance, it often presents a specific shape, or is crystalline, with a regular crystal structure, reflecting the orderly arrangement of molecules; or is powdery, with fine and uniform texture, mostly white or close to white, and the color is whiter when the purity is high. This appearance characteristic is affected by the preparation process and purity.
    Melting point is of great significance to this compound and is a key indicator of its physical properties. Under different conditions, the melting point will fluctuate in a certain range. Accurate determination of the melting point is crucial for identification and purity judgment. Its purity can be evaluated by melting point measurement. The presence of impurities will reduce the melting point and widen the melting range.
    In terms of solubility, the compound has different performances in specific organic solvents. In some organic solvents such as ethanol and acetone, it may have good solubility and can form a uniform solution, which is convenient for chemical reaction and analysis; while in water, the solubility may be poor, which is related to the molecular structure and polarity. The molecular polarity is greatly different from water, making it difficult to dissolve in water. The solubility characteristics need to be taken into account when separating, purifying and selecting reaction solvents.
    Density is also an important physical property. Although it varies due to specific measurement conditions, it is relatively fixed. The density data is of great significance in material calculation, separation process and mixing with other substances, which helps to determine its position and behavior in the mixture.
    In addition, the compound may be volatile to some extent, but the volatility is weak, requiring specific conditions and instrument testing. Volatility affects its storage and use environment, and it needs to be sealed to prevent volatile loss and environmental pollution.
    2- [ (R) - [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] sulfinyl] -1H-benzimidazole What are the applications in the field of medicine?
    In the field of medicine, this compound "2 - [ (R) - [3 - methyl - 4 - (2,2,2 - trifluoroethoxy) -2 - pyridyl] methyl] sulfonylphenyl - 1H - benzimidazole" has important applications.
    One of its main applications is in the treatment of digestive system diseases. It can effectively inhibit gastric acid secretion, by inhibiting the proton pump on the cells of the stomach wall, thereby reducing gastric acid production. Diseases such as gastric ulcers, duodenal ulcers, and reflux esophagitis are mostly caused by excessive gastric acid secretion or acid reflux. This compound plays a key role in alleviating the symptoms of these diseases and promoting ulcer healing. For example, for patients with gastric ulcers, long-term administration of drugs containing this compound can significantly improve symptoms such as stomach pain and acid reflux, and improve the quality of life of patients.
    In addition, this compound also plays an important role in the treatment plan for the eradication of Helicobacter pylori. Helicobacter pylori infection is closely related to a variety of gastric diseases. Combining this compound with antibiotics can improve the eradication rate of Helicobacter pylori and prevent the recurrence and progression of gastric diseases. In practical clinical applications, this combination therapy has become one of the standard solutions for the treatment of Helicobacter pylori infection-related diseases, bringing hope for recovery to many patients.
    What are the synthesis methods of 2- [ (R) - [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] sulfinyl] -1H-benzimidazole?
    To prepare 2 - [ (R) - [3 - methyl - 4 - (2,2,2 - trifluoroethoxy) -2 - pyridyl] methyl] - 1H - benzimidazole, there are many synthesis methods.
    First, you can start from the compound containing pyridyl group. First, replace the specific position on the pyridine ring with a suitable reagent, introduce methyl, 2,2 - trifluoroethoxy and other groups, carefully control the reaction conditions, such as temperature, pH and reactant ratio, to ensure accurate substitution check point. Next, through a condensation reaction, the modified pyridyl group is connected to the benzimidazole parent nucleus. This process requires a high-efficiency catalyst to improve the reaction efficiency and selectivity.
    Second, benzimidazole is used as the starting material. The 2-position of benzimidazole is activated first, and then reacted with the pyridine-containing structure fragment. The construction of the pyridine fragment is crucial to ensure that the structures such as 3-methyl, 4- (2,2,2-trifluoroethoxy) and 2-pyridyl are properly assembled. In the construction of pyridine fragments, 2,2,2-trifluoroethoxy groups can be introduced by the reaction of halogenated hydrocarbons with sodium alcohol, and then methyl groups can be introduced through suitable alkylation reactions.
    Third, the stepwise construction method is adopted. First synthesize intermediates containing part of the target structure, and then splice these intermediates. For example, first synthesize intermediates containing pyridine fragments and part of the benzimidazole structure, and then build a complete benzimidazole ring through cyclization reaction. During this period, the reaction conditions need to be carefully regulated to avoid side reactions.
    When synthesizing this compound, the purity of the raw material, the precise control of the reaction conditions, and the separation and purification of the intermediate are all key, which have a great impact on the yield and purity of the final product.
    What are the market prospects for 2- [ (R) - [3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] sulfinyl] -1H-benzimidazole?
    There is now a product named 2- [ (R) - [[3-methyl-4- (2,2,2-trifluoroethoxy) -2 -pyridyl] methyl] sulfinyl] -1H -benzimidazole. I will analyze it in detail using the method of ancient times.
    Looking at the structure of this product, its chemical composition is unique, containing special groups and structures, which may give it unique physical, chemical and biological activities. In the field of medicine, such structures may have pharmacological potential. If they can exhibit good biological activity and low toxicity, they can be used as lead compounds for the development of new drugs. Nowadays, there is a strong demand for new drugs in the pharmaceutical market, especially for specific drugs for difficult diseases. If this product can be developed into an effective treatment drug, its market prospect may be extremely broad, and it can be paid attention and invested by many pharmaceutical companies.
    In the chemical industry, its unique structure may make it possible to apply in materials, catalysts, etc. With the pursuit of high-performance and special functional materials in the chemical industry, if this product can meet specific needs, such as improving material stability and catalytic activity, it can also occupy a place in the chemical market.
    However, to gain a good market prospect, it also faces many challenges. The research and development process requires a lot of manpower, material resources and time to confirm its safety, effectiveness and quality controllability. And the market competition is fierce, and similar or alternative products also pose a threat to it. If you can overcome the R & D difficulties and stand out with unique advantages, you will be able to achieve great results in the market and have a bright future; if it is difficult to break through the difficulties, it may be difficult to have significant market action.