2-(naphthalene-1-yl)-1-tosyl-1H-benzoimidazole

2-% 28 naphthalene-1-yl% 29-1-p-toluenesulfonyl-1H-benzimidazole, this is an organic compound. Its chemical structure is quite complex and delicate.
The core structure of this compound is a benzimidazole ring, which is fused from a benzene ring and an imidazole ring, giving it unique chemical activity and stability. Above the 1 position, there is a p-toluenesulfonyl group, which contains a benzene ring and a sulfonyl group. The benzene ring adds a conjugated system of molecules, which makes the electron cloud distribution of the molecule more extended, and the strong electron-absorbing properties of the sulfonyl group have a significant impact on the electron cloud density and reactivity of the whole molecule. < Br >
At the second position, naphthalene-1-yl is connected. Naphthalene is a fused aromatic hydrocarbon with a large conjugate system. The introduction of naphthalene bases greatly expands the conjugate range of the molecule, enhances the rigidity and planarity of the molecule, and then affects its physical and chemical properties, such as photophysical properties and intermolecular interactions.
This compound may have potential applications in many fields such as materials science and medicinal chemistry due to its unique chemical structure. In the field of materials, or with its conjugated structure and electronic properties, it can be applied to organic optoelectronic materials, such as organic Light Emitting Diodes, organic solar cells, etc.; in the field of medicinal chemistry, its complex structure may provide a variety of possibilities for interaction with biological targets. After structural modification and optimization, it may be developed into drugs with specific biological activities.

2-% 28naphthalene - 1 - yl% 29 - 1 - tosyl - 1H - benzoimidazole, that is, 2 - (naphthalene - 1 - yl) - 1 - p-toluenesulfonyl - 1H - benzimidazole, this substance is widely used.
First, in the field of organic synthesis, it is often used as a key intermediate. With its unique chemical structure, other nitrogen-containing heterocyclic compounds can be derived through various chemical reactions. For example, through the nucleophilic substitution reaction under specific conditions, it can be combined with different nucleophilic reagents to build compounds with more complex structures, providing key starting materials for organic synthesis chemists to create novel molecular structures and develop new substances in the fields of drugs and materials.
Second, in the field of pharmaceutical chemistry, it has shown potential medicinal value. Studies have shown that such benzimidazole-containing compounds have affinity and activity for certain biological targets. Or they can be used as lead compounds. After structural modification and optimization, they can improve the selectivity and inhibition or activation ability of specific disease-related targets, and are expected to be developed into innovative drugs against diseases such as tumors and inflammation.
Third, in the field of materials science, due to its special electronic structure and optical properties, it can be applied to optoelectronic materials. Or materials with specific photoluminescence or electroluminescence properties can be prepared for optoelectronic devices such as organic Light Emitting Diodes (OLEDs) to improve the luminous efficiency and stability of the devices, and help the development of display technology and lighting.
Fourth, in the field of coordination chemistry, its nitrogen atom can be used as a check point to coordinate with metal ions to form metal complexes. These complexes may have unique physical and chemical properties, such as catalytic properties, magnetism, etc., and have potential applications in catalytic reactions, magnetic materials, etc.

To prepare 2 - (naphthalene - 1 - yl) - 1 - toluenesulfonyl - 1H - benzimidazole, the method is as follows:
First take an appropriate amount of 1 - naphthalamine and o-phenylenediamine, use an appropriate organic solvent as a medium, such as ethanol or dichloromethane, at a suitable temperature, such as 50 to 80 degrees Celsius, stir and mix, this step aims to make 1 - naphthalamine and o-phenylenediamine condensation reaction. During the reaction, pay attention to the change of the reaction system, observe the change of its color and state, and observe the reaction process.
After the first step of the reaction is completed, the reaction product is mixed with p-toluenesulfonyl chloride, and also in an organic solvent, such as dichloromethane, and an appropriate amount of acid binding agent, such as triethylamine, is added to promote the reaction. The reaction temperature should be controlled between room temperature and 40 degrees Celsius, and the two should be stirred continuously to fully react. The key to this step lies in the control of the amount of acid binding agent and the reaction temperature. Too much or too little dosage, too high or too low temperature may affect the yield and purity of the product.
After the reaction is completed, the product is separated and purified. The organic solvent is first removed by conventional methods, such as vacuum distillation. Then column chromatography was used to separate the product with silica gel as the stationary phase and a suitable proportion of petroleum ether and ethyl acetate mixture as the mobile phase to obtain a pure 2- (naphthalene-1-yl) -1 -toluenesulfonyl-1H -benzimidazole. During operation, pay attention to the flow rate and ratio of the mobile phase to ensure the separation effect.
Throughout the synthesis process, each step requires fine operation and attention to the control of reaction conditions, so as to obtain the target product.

2-% 28 naphthalene-1-yl% 29-1-p-toluenesulfonyl-1H-benzimidazole, this substance has unique properties and has multiple physical and chemical characteristics. Its appearance is often crystalline, white and pure, just like jade carving.
In terms of solubility, it can be better dissolved in organic solvents, such as dichloromethane, chloroform, etc., just like fish entering water. But in water, it is hard to find its trace, just like a hermit who does not enter the world, and it is extremely difficult to dissolve.
In terms of melting point, it is about a specific temperature range, and this temperature is like its "personality temperature". When it reaches it, it melts, showing the wonders of its physical state transformation.
In terms of stability, when it is quiet at room temperature and pressure, it is like a humble gentleman, stable and peaceful. However, if it encounters strong acids and alkalis, it seems to encounter foreign enemies, structure or change, and stability is challenged.
Its spectral properties are also considerable. In the infrared spectrum, specific chemical bonds such as benzene rings and imidazole rings, each with its own unique music notes, play the movement of characteristic absorption peaks, and draw a beautiful picture for its structure analysis. In the ultraviolet spectrum, and because of the conjugate system, a unique absorption band appears, just like a dark night star, indicating its existence and characteristics.

I am looking at the price range of "2- (naphthalene - 1 - yl) -1 - tosyl - 1H - benzoimidazole" you are inquiring about in the market. This is a fine chemical, and its price varies due to many reasons.
If it is difficult to say from its preparation, the synthesis of this compound may require multiple steps of reaction, and the requirements for reaction conditions may be strict, and the raw materials may be rare, resulting in high preparation costs and high prices.
Looking at the supply and demand in the market, if there are many people who need it, and there are few producers, the price will rise; on the contrary, if the supply exceeds the demand, the price may drop. < Br >
And its purity affects the price very much. High purity is more difficult to prepare, and the price is higher than that of low purity. Generally speaking, the laboratory purchases in small quantities, if the purity is ordinary, the price per gram may be between tens and hundreds of yuan; if high purity is required and large quantities are used in industrial production, due to economies of scale, the unit price may drop, but the price per kilogram may still be thousands of yuan. However, this is only a rough estimate. The actual price should be consulted with the chemical raw material supplier, subject to the current market price.