2-n-Butyl-4(5)-Chloro-1H-Imidazole-5(4)-Carboxaldehyde

2-N-butyl-4 (5) -chloro-1H-imidazole-5 (4) -carboxyaldehyde, which has a wide range of uses. In the field of medicinal chemistry, it is often the key intermediate for the synthesis of many specific drugs. Geinimidazole compounds have unique chemical structures and biological activities. Based on this, drugs with excellent effects such as antibacterial, antiviral, and anti-tumor can be carefully constructed.
It can also be seen in the field of materials science. Because of its special functional groups, it can participate in the modification and synthesis of materials, enabling materials to obtain excellent properties such as better stability and adsorption, so it is often used in the creation of new functional materials.
In the field of organic synthetic chemistry, it plays an important role. As an active intermediate, it can build complex organic molecular structures with the help of various chemical reactions, providing an effective way for the synthesis of novel organic compounds, helping chemists explore more unknown chemical spaces, and promoting the continuous development of organic synthetic chemistry.
In short, 2-n-butyl-4 (5) -chloro-1H-imidazole-5 (4) -carboxyaldehyde has shown indispensable value in many fields due to its unique structure and active reactivity, promoting the continuous progress and innovation of related science and technology.

To prepare 2-n-butyl-4 (5) -chloro-1H-imidazole-5 (4) -formaldehyde, there are many methods, and each has its own advantages.
First, we can start from common starting materials and borrow the classic reaction of organic synthesis. For example, first take the imidazole derivative containing a specific substituent, make it with halobutane under suitable reaction conditions, use base as catalyst, carry out nucleophilic substitution reaction, and introduce n-butyl at the 2-position of imidazole. Then, the obtained product is chlorinated, and the reaction check point is precisely controlled, and chlorine atoms are introduced at the 4 (5) -position. As for the introduction of aldehyde groups, suitable oxidants can be used to oxidize specific groups, but this process requires careful regulation of the reaction conditions to prevent excessive oxidation.
Second, the strategy of multi-step series reaction can also be considered. By ingeniously designing the reaction sequence, several steps can be reacted continuously in the same reaction system, reducing the separation and purification steps of intermediates, which not only improves the reaction efficiency but also reduces the cost. For example, the starting material is cyclized to construct an imidazole ring, and some required substituents are introduced at the same time, followed by alkylation, halogenation, and aldehyde-ylation reactions. Each step requires fine regulation of reaction temperature, reaction time, and reactant ratio to achieve ideal yield and selectivity.
Furthermore, refer to the mature methods reported in the relevant literature and optimize them. Some predecessors may have studied the synthesis of compounds with similar structures, and they can learn from their ideas and methods, combine the characteristics of the target product, and fine-tune the reaction conditions and reagents used. In this way, more efficient and green synthesis paths may be found, and in the field of organic synthesis, continuous exploration and innovation can be made to achieve the best synthesis effect.

2-Butyl-4 (5) -chloro-1H-imidazole-5 (4) -carboxyaldehyde, which is an organic compound. Its physical properties are particularly important for its application in various fields.
Bearing the brunt, look at its appearance. Under normal temperature and pressure, this substance often takes a specific form. Or a crystalline solid, like fine grains, crystal clear and regular, reflected by light, flickering shimmering; or a viscous liquid, flowing with a unique texture, color or clear and transparent, or a slight band of color, as if hiding the inner chemical mystery. < Br >
times and melting point and boiling point. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point of this compound, when accurately measured, has a specific value. When the temperature gradually rises to the melting point, the force between molecules is gradually weakened, the lattice structure begins to disintegrate, and the solid state gradually melts into a liquid state. The boiling point is the temperature at which a substance changes from a liquid state to a gas state under a specific pressure. At standard pressure, its boiling point is also fixed. When it reaches the boiling point, the interior of the liquid is violently vaporized, and the molecules break free from the liquid phase and escape into the gas phase.
Furthermore, solubility is also a key property. In different solvents, its performance varies. In organic solvents such as ethanol and acetone, or show good solubility, can interact with solvent molecules, disperse uniformly, and form a uniform solution. In water, or poor solubility, due to the characteristics of molecular structure, the interaction with water molecules is weak, or partially soluble, or insoluble state, in water or now stratified, or precipitated.
In addition, density is also one of its physical properties. By accurate measurement, the mass per unit volume can be obtained. This value reflects the degree of compactness of molecular accumulation, and in practical applications, such as in mixed systems, it is related to its stratification, flow and other characteristics.
has a refractive index, which is a measure of the degree of refraction when light passes through the substance. The specific refractive index reflects the characteristics of the action of substance molecules on light, which can be used as an important basis for identification and purity detection.
The above physical properties are interrelated and together outline the physical "picture" of 2-n-butyl-4 (5) -chloro-1H-imidazole-5 (4) -carboxyaldehyde, providing a solid foundation for its synthesis, separation, purification and application.

2-N-butyl-4 (5) -chloro-1H-imidazole-5 (4) -formaldehyde, this is an organic compound. Its chemical properties are unique and have a variety of characteristics.
Let's talk about its physical properties first, usually solid, color or nearly colorless to slightly yellow, like a crystalline powder, and it looks fine. The melting point is in a specific range, which varies depending on the purity. Generally speaking, it will melt into a liquid state at moderate temperatures. This property is crucial for the separation, purification and identification of compounds, like a key to open the door to treasure.
In terms of chemical activity, the imidazole ring of this compound is the core structure, giving it unique reactivity. The presence of aldehyde groups allows it to participate in many classical organic reactions. For example, it can react with alcohols in acetal. This reaction is often used in organic synthesis to protect aldehyde groups or build complex carbon-oxygen bond structures, just like the building blocks of skilled craftsmen to build exquisite buildings. It can also react with amines to form Schiff bases. Schiff bases are widely used in coordination chemistry and drug synthesis, and are like an important cornerstone for building a chemical building.
Furthermore, the introduction of chlorine atoms greatly changes the distribution of molecular electron clouds and affects their nucleophilic substitution reactivity. Due to the electron-absorbing properties of chlorine atoms, the electron cloud density on the imidazole ring is reduced, and it is more vulnerable to attack by nucleophilic reagents, just like in the battlefield, the weakness is more easily broken by the enemy. Therefore, the nucleophilic substitution reaction of halogenated hydrocarbons is common, and this compound can also proceed smoothly, opening up many paths for the synthesis of novel derivatives.
Its chemical stability requires special attention under specific conditions. In the case of strong acids, strong bases or high temperature environments, the molecular structure may change, triggering decomposition or rearrangement reactions. Just like fragile works of art, if the environment is not good, it will be easily damaged. Therefore, care should be taken when storing and using, and environmental conditions should be properly controlled to ensure its chemical stability.

I look at what you said about "2 - n - Butyl - 4 (5) - Chloro - 1H - Imidazole - 5 (4) - Carboxaldehyde", which is a chemical substance. However, it is not easy to know its market price.
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