2 Methyl 5 Nitroimidazole 1 Et
quinoline thiophene imidazole thiazole

2-Methyl-5-nitroimidazole-1-et

    Specifications

    HS Code

    835424

    Chemical Formula C5H7N3O3
    Molar Mass 157.13 g/mol
    Appearance Solid
    Melting Point 190 - 192 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents
    Odor Odorless
    Color White to off - white

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    General Information
    Where to Buy 2-Methyl-5-nitroimidazole-1-et in China?
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    Frequently Asked Questions

    As a leading 2-Methyl-5-nitroimidazole-1-et supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2-Methyl-5-nitroimidazole-1-et?
    2-Methyl-5-nitroimidazole-1-ethanol, this is an organic compound. Looking at its name, it can be seen that its structure is formed by connecting several parts.
    The first is the imidazole ring, which has a dinitrogen atom and forms an unsaturated five-membered ring, which is structurally stable and highly reactive. At the second position of the imidazole ring, there is a methyl group, that is, -CH. The introduction of methyl groups, or the change of molecular space structure, has an impact on its physical and chemical properties, such as solubility and boiling point.
    At the fifth position of the imidazole ring, there is a nitro group, that is, -NO. The nitro group is a strong electron-absorbing group, and its existence greatly increases the polarity of the molecule, and affects the electron cloud distribution of the imidazole ring, which in turn affects the reactivity and chemical properties of the compound.
    The first position of the imidazole ring is connected to the ethanol group, that is, -CH -2 CH -2 OH OH. The ethanol group contains hydroxyl-OH, which is hydrophilic, or can increase the solubility of the compound in polar solvents, and the hydroxyl group can participate in a variety of chemical reactions, such as esterification, dehydration, etc.
    In summary, the structure of 2-methyl-5-nitroimidazole-1-ethanol is composed of imidazole ring as the core, combined with methyl, nitro and ethyl alcohol groups, and the interaction of each part determines the unique physicochemical properties and reactivity of the compound.
    What are the main uses of 2-Methyl-5-nitroimidazole-1-et?
    2-Methyl-5-nitroimidazole-1-ethanol has a wide range of uses. In the field of medicine, this is an important pharmaceutical intermediate and is often the key starting material for the synthesis of antibacterial and antibacterial drugs. For example, nitrazole drugs are effective in combating anaerobic bacteria, trichomonas and other infections, while 2-methyl-5-nitroimidazole-1-ethanol is indispensable for the synthesis of such drugs. Due to its structural characteristics, it can participate in complex chemical reactions and undergo a series of transformations, giving the final drug unique pharmacological activity, helping the drug to accurately act on pathogens and achieve therapeutic purposes.
    In the chemical industry, it also plays an important role in the field of organic synthesis. It can be used as a key component in the synthesis of special functional materials, imparting specific chemical properties and functions to materials. For example, in the preparation of some polymer materials with special requirements for stability and reactivity, it can participate in the polymerization reaction as a functional monomer, changing the microstructure of the material, so that the material has better chemical stability, thermal stability or special reactivity to meet the needs of different industrial scenarios.
    In addition, in terms of scientific research and exploration, it provides important samples for organic chemistry and medicinal chemistry research as compounds with specific structures and activities. Researchers can use the study of its reaction characteristics and structural modification to explore new chemical reaction paths, discover new biological activities, and open up new directions for the development of chemistry and medicine.
    2-methyl-5-nitroimidazole-1-ethanol, with its unique chemical structure, plays an important role in many fields such as medicine, chemical industry, scientific research, etc., and is of great significance for promoting technological progress and industrial development in related fields.
    What are 2-Methyl-5-nitroimidazole-1-et production methods?
    The preparation method of 2-methyl-5-nitroimidazole-1-ethanol has been known for a long time. There are many methods, and I will describe them here.
    First, 2-methyl-5-nitroimidazole is used as the starting material and interacts with ethylene oxide under suitable reaction conditions. When reacting, pay attention to temperature, pressure and reaction time. If the temperature is too high, side reactions will breed; if the temperature is too low, the reaction will be slow and difficult. The pressure also needs to be appropriate to make the reaction smooth. The reaction time also needs to be precisely controlled. If it is too short, the reaction will not be completed, and if it is too long, it will consume resources. In this process, the selection of a suitable catalyst can accelerate the reaction process and improve the yield of the product.
    Second, 2-methyl-5-nitroimidazole and halogenated ethanol can also be used as raw materials. The activity of halogen atoms in halogenated ethanol has a great impact on the reaction. Generally speaking, iodine ethanol has the highest activity, followed by bromine, followed by chlorine. The reaction is usually carried out in an alkaline environment, and the strength and dosage of bases need to be carefully considered. Too strong bases or too much base may cause the decomposition of raw materials or cause other side reactions.
    Furthermore, other more complex organic synthesis paths can also be used. For example, the specific functional group modification of 2-methyl-5-nitroimidazole is first carried out, and then converted into the target product through multi-step reaction. Although this path has many steps, the purity and structure of the product can be fine-tuned according to actual needs.
    Preparation of 2-methyl-5-nitroimidazole-1-ethanol, each method has its advantages and disadvantages, and it is necessary to comprehensively consider the actual production conditions, raw material availability, product purity requirements and many other factors, and carefully choose the appropriate method to achieve the best production effect.
    What are the physical and chemical properties of 2-Methyl-5-nitroimidazole-1-et
    2-Methyl-5-nitroimidazole-1-ethanol is an organic compound. Its physicochemical properties are crucial and are relevant to many fields of application.
    When it comes to its properties, it may be solid under normal conditions, and it has a certain stability due to the specific groups contained in the molecular structure. From the perspective of solubility, it may have a certain solubility in some organic solvents, but its solubility in water may be limited. Because the compound molecule contains hydrophobic methyl and nitro groups, it reduces its ability to interact with water molecules.
    Melting point and boiling point are also important physicochemical properties. The melting point depends on the intermolecular force. There are van der Waals forces and possible hydrogen bonds between the molecules of this compound, so that its melting point is in a specific range. The boiling point is the same, and it is determined by the intermolecular force and the relative molecular mass.
    In terms of chemical properties, because of its nitro and imidazole ring structure, it has certain reactivity. Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the imidazole ring and affect the substitution reactivity on the ring. In case of nucleophilic reagents, or nucleophilic substitution reactions occur at specific positions of the imidazole ring. And under appropriate conditions, the compound may participate in the redox reaction, and the nitro part can be reduced. Furthermore, due to the presence of alcohol hydroxyl groups, typical alcohols can react, such as esterification with acids, to form corresponding ester compounds. This reaction is widely used in the field of organic synthesis and can be used to prepare derivatives with specific functions.
    2-Methyl-5-nitroimidazole-1-et what are the precautions during use
    For 2-methyl-5-nitroimidazole-1-ethanol, there are many things to pay attention to when using it. This substance has specific chemical properties and uses, and needs to be treated with caution.
    First, it is related to storage. Be sure to store in a cool, dry and well-ventilated place, away from fire and heat sources. Because it may have certain chemical activity, improper storage environment or deterioration will affect its performance, and even pose a risk of safety.
    Second, when using the operation, it is necessary to uphold a strict attitude. Appropriate protective equipment, such as gloves, goggles, etc., should be worn. Due to its chemical characteristics, or irritation or even damage to the skin and eyes, protective equipment can protect the human body from harm. The operation should be carried out in a fume hood to prevent the accumulation of harmful gases and endanger personal health.
    Third, during use, the dosage must be precisely controlled. According to the needs of the experiment or production, strictly follow the established standards and procedures, and measure accurately. Improper dosage, or the reaction is not as expected, or an unexpected situation occurs.
    Fourth, pay attention to its compatibility with other substances. Before mixing with other chemical substances, it is necessary to clarify whether the two will have adverse reactions. Mixing rashly, or causing a violent reaction, can cause a safety accident.
    Fifth, after use, the residue and waste should be properly disposed of in accordance with relevant regulations. Do not discard at will, so as not to pollute the environment and prevent adverse effects on subsequent links.
    In short, the use of 2-methyl-5-nitroimidazole-1-ethanol, from storage, operation to waste disposal, all need to be careful and follow the norms to ensure safety and effectiveness.