2 Methyl 4 5 Dihydro 1h Imidazole
quinoline thiophene imidazole thiazole

2-methyl-4,5-dihydro-1H-imidazole

    Specifications

    HS Code

    105154

    Chemical Formula C4H8N2
    Molar Mass 84.12 g/mol
    Appearance Typically a colorless to pale yellow liquid
    Odor Characteristic amine - like odor
    Boiling Point Data may vary, around 190 - 200 °C under normal pressure
    Density Approximate density around 1.0 - 1.1 g/cm³
    Solubility In Water Moderately soluble in water due to polar nature of the imidazole ring
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Flash Point Should be determined experimentally, but likely flammable as an organic amine - containing compound

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    Frequently Asked Questions

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    2-Methyl-4, what are the chemical properties of 5-dihydro-1H-imidazole?
    2-Methyl-4,5-dihydro-1H-imidazole is an organic compound with many unique chemical properties.
    From the structural point of view, this compound contains an imidazole ring, which is aromatic. Although the 4,5 positions are dihydro states, it still has a great influence on its properties. The methyl substituent at the 2 position can change the distribution of molecular electron clouds due to its electron-induced effect.
    In terms of basicity, the nitrogen atom of the imidazole ring has an isolated pair of electrons, which can accept protons, and is basic. The electron-given action of the methyl group increases the electron cloud density of the nitrogen atom and enhances the basicity.
    In the nucleophilic reaction, due to the electron-rich nitrogen atom, 2-methyl-4,5-dihydro-1H-imidazole can act as a nucleophilic reagent and react with the electrophilic reagent, such as with halogenated hydrocarbons. The nitrogen atom attacks the carbon atom of the halogenated hydrocarbon to form a substitution product.
    Regarding its stability, the aromatic structure of the imidazole ring imparts a certain stability to the molecule. However, the dihydrogen structure of the 4,5 position is slightly less stable than the imidazole of the complete aroma. Under certain conditions, reactions such as oxidation or addition can occur.
    In addition, 2-methyl-4,5-dihydro-1H-imidazoline contains nitrogen atoms, which can be complexed with metal ions to form coordination compounds. This property may have application potential in the fields of catalysis and materials science.
    In summary, the special structure of 2-methyl-4,5-dihydro-1H-imidazoline shows chemical properties such as alkalinity, nucleophilicity, specific stability and complexing ability, and has important research value and application prospects in many fields such as organic synthesis and pharmaceutical chemistry.
    What are the common uses of 2-methyl-4, 5-dihydro-1H-imidazole?
    2-Methyl-4,5-dihydro-1H-imidazole (2-methyl-4,5-dihydro-1H-imidazole) is one of the organic compounds and has its common uses in many fields.
    In the field of pharmaceutical chemistry, this compound is often used as a key intermediate in drug synthesis. Due to its unique structure, it can interact with specific targets in organisms. For example, when developing antibacterial drugs, the 2-methyl-4,5-dihydro-1H-imidazole structure can be modified to conform to the activity check point of specific enzymes in bacteria, thereby inhibiting bacterial growth and reproduction. Or when developing anti-tumor drugs, by modifying its structure, it can interfere with the metabolic pathway of tumor cells and achieve the purpose of inhibiting the proliferation of tumor cells.
    In the field of materials science, 2-methyl-4,5-dihydro-1H-imidazole can be used to prepare functional materials. For example, it can participate in the synthesis of polymers, giving polymers special properties. If it is introduced into polymer materials, it can improve the thermal stability and mechanical properties of the materials. Because its structure contains nitrogen heterocycles, it can form hydrogen bonds or coordination bonds with other molecules, which in turn affects the aggregate structure and properties of the materials.
    In the field of organic synthetic chemistry, 2-methyl-4,5-dihydro-1H-imidazole is an important synthetic building block, which can construct more complex organic molecular structures through various chemical reactions, such as nucleophilic substitution and cyclization. Chemists can use its active chemical properties to introduce different functional groups into its molecules to expand the structural diversity of organic compounds and provide rich possibilities for the creation of new compounds.
    What are the synthesis methods of 2-methyl-4, 5-dihydro-1H-imidazole?
    2-Methyl-4,5-dihydro-1H-imidazole is an organic compound, and its synthesis methods are various, so let me tell you one by one.
    First, glyoxal, acetaldehyde and methylamine are used as raw materials. Under suitable reaction conditions, the three are first condensed to form key intermediates, and then cyclized to obtain 2-methyl-4,5-dihydro-1H-imidazole. During this period, the reaction temperature, the proportion of reactants and the choice of catalyst all have a great influence on the reaction process and product yield. In general, controlling the reaction temperature in a moderate range, accurately adjusting the proportion of reactants, and selecting high-efficiency catalysts can promote the smooth progress of the reaction in the desired direction and improve the yield of the product.
    Second, specific nitrogen-containing compounds can also be used to react with carbonyl compounds. Nucleophilic addition of nitrogen-containing compounds to carbonyl compounds is first performed, followed by intracellular cyclization, and the target product can also be obtained. In this method, it is equally important to control the reaction conditions, such as the choice of reaction solvent and the control of reaction time. Fine operation is required to ensure the high efficiency of the reaction and the purity of the product.
    Third, through the modification and synthesis of imidazole derivatives. Select suitable imidazole derivatives, introduce or modify them with specific groups, and then obtain 2-methyl-4,5-dihydro-1H-imidazole. This process requires in-depth understanding of the chemical properties of imidazole derivatives, ingenious design of reaction routes, and rational use of various organic synthesis methods to achieve the established synthesis goals.
    There are many methods for synthesizing 2-methyl-4,5-dihydro-1H-imidazole, but they all need to be based on the actual situation, such as the availability of raw materials, the ease of control of reaction conditions, the purity and yield requirements of the product, etc., carefully select the appropriate synthesis path, and carefully optimize the reaction conditions in order to achieve efficient and high-quality synthesis.
    2-Methyl-4, 5-dihydro-1H-imidazole is widely used in which areas?
    2-Methyl-4,5-dihydro-1H-imidazole is widely used in many fields such as medicine, materials science, and organic synthesis.
    In the field of medicine, it plays a crucial role. This compound has a unique chemical structure and properties, and can interact with specific targets in organisms. For example, many studies have shown that it may be used as a potential drug intermediate. After chemical modification, it is expected to develop new drugs for the treatment of specific diseases. Because its structure can participate in a variety of biochemical reactions, or can regulate physiological processes in organisms, it has great potential in the development of antibacterial, antiviral and antitumor drugs.
    In the field of materials science, 2-methyl-4,5-dihydro-1H-imidazole also exhibits unique properties. It can be used to prepare special polymer materials and endow materials with special properties. For example, when preparing functional polymers, introducing them into polymer structures may improve the thermal stability, mechanical properties and chemical stability of polymers. Because it can react with other monomers to form copolymers with special properties, it is used in aerospace, electronic devices and other fields that require strict material properties.
    In the field of organic synthesis, 2-methyl-4,5-dihydro-1H-imidazole is a commonly used intermediate in organic synthesis. Due to its reactivity, it can participate in many organic reactions, such as nucleophilic substitution, cyclization, etc. With the help of such reactions, chemists can construct complex organic molecular structures and provide an effective way for the synthesis of new organic compounds. And it may also have applications in the field of catalysis. It can be used as an organic catalyst to promote specific organic reactions, showing unique catalytic activity and selectivity.
    2-Methyl-4, 5-dihydro-1H-imidazole market prospects?
    2-Methyl-4,5-dihydro-1H-imidazole is one of the organic compounds. Its market prospects are multi-faceted.
    From the perspective of the pharmaceutical field, such compounds have great potential. Among many drug development, 2-methyl-4,5-dihydro-1H-imidazole is often a key intermediate. Its unique structure can be chemically modified to synthesize drug molecules with diverse biological activities. For example, the creation of antihistamines, based on this, can effectively regulate the body's immune response and relieve allergic symptoms. Due to the large number of allergy patients at present, the demand for anti-allergy drugs continues to grow, so in this field, the market prospect of 2-methyl-4,5-dihydro-1H-imidazole is broad.
    In the field of materials science, it is also promising. Because it contains specific functional groups, it can participate in the synthesis of polymer materials. The polymers prepared therefrom may have special physical and chemical properties, such as excellent thermal stability, mechanical properties, etc. These materials can be used in high-end fields such as aerospace and automobile manufacturing. Where the material properties are stringent, such unique materials are required. With the advancement of science and technology, the high-end manufacturing industry has an increasing demand for special materials, and the market for 2-methyl-4,5-dihydro-1H-imidazole is expected to expand in this field.
    However, its market development also faces challenges. The process of synthesizing this compound may have the disadvantages of high storage costs and cumbersome steps. If it is to be used on a large scale, it is necessary to optimize the synthesis route and reduce production costs. And the market competition is fierce, and many chemical companies are concerned about such compounds. Only by constantly innovating technologies and improving product quality can we gain an advantage in the market.
    In summary, although 2-methyl-4,5-dihydro-1H-imidazole has promising prospects in the fields of medicine and materials, it is necessary to deal with problems such as synthesis process and competition in order to fully explore its market potential. Through technological innovation and optimization strategies, we can seek broad market development space.