2 Methyl 1h Benzimidazole 5 Carboxylic Acid
quinoline thiophene imidazole thiazole

2-methyl-1H-benzimidazole-5-carboxylic acid

    Specifications

    HS Code

    509912

    Chemical Formula C9H8N2O2
    Molecular Weight 176.17
    Iupac Name 2 - methyl - 1H - benzimidazole - 5 - carboxylic acid
    Appearance Solid (expected, typical for such organic compounds)
    Melting Point No common value found (data may vary based on purity etc.)
    Boiling Point No common value found (data may vary based on purity etc.)
    Solubility In Water Low (organic acid with non - polar benzimidazole part)
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Pka No common value found (acidic due to carboxylic acid group)
    Color Colorless to light - colored (expected for this type of compound)
    Odor Odorless or mild odor (typical for many benzimidazole derivatives)

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    General Information
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    Frequently Asked Questions

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    What is the chemistry of 2-methyl-1H-benzimidazole-5-carboxylic acid?
    2-Methyl-1H-benzimidazole-5-carboxylic acid, this is an organic compound. It has unique chemical properties.
    Looking at its structure, the benzimidazole ring is the core, with a methyl group at the 2nd position and a carboxyl group at the 5th position. Because it contains a carboxyl group, it is acidic. It can react with a base to form a corresponding carboxylate. This reaction is a common type of acid-base neutralization. Just like titrating a solution containing this acid with a alkali solution, hydrogen ions can combine with hydroxyl ions to form water and obtain carboxylate. < Br >
    Because of its nitrogen-containing heterocyclic structure, the nitrogen atom has a solitary pair of electrons, which makes the compound exhibit a certain alkalinity and can react with strong acids and protonate to form corresponding salts.
    The stability of this compound is also worthy of attention. The conjugate system of the benzimidazole ring gives it a certain stability. However, the existence of carboxyl groups, due to the electron-withdrawing property of the carboxyl group, or the electron cloud distribution of the benzimidazole ring, affects the overall stability.
    In terms of reactivity, carboxyl groups can participate in many organic reactions, such as esterification reactions, and under the action of catalysts with alcohols, ester compounds and water are formed. In this process, the hydroxyl group of the carboxyl group is replaced by the alkoxy group of The nitrogen atom on the benzimidazole ring may participate in nucleophilic reactions, because the lone pair electron can be used as a nucleophilic reagent to attack suitable electrophilic reagents.
    2-methyl-1H-benzimidazole-5-carboxylic acid has potential applications in organic synthesis, medicinal chemistry and other fields due to its unique structure. Its acid-base properties and reactivity lay the foundation for various reactions.
    What are the main uses of 2-methyl-1H-benzimidazole-5-carboxylic acid?
    2-Methyl-1H-benzimidazole-5-carboxylic acid, this is an organic compound. It has a wide range of uses in the field of medicine or is a key intermediate in drug synthesis. Due to its unique chemical structure, it may endow drugs with specific biological activities, such as participating in the preparation of anti-tumor and antiviral drugs. By interacting with targets in organisms, physiological processes can be regulated to achieve the effect of treating diseases.
    It also has important applications in the field of materials science. It can be used as a basic raw material for the construction of new functional materials. After specific chemical reactions, polymers or other material systems are introduced to improve material properties, such as improving material stability, optical properties or electrical properties. It has potential applications in optoelectronic materials, polymer materials, etc.
    In agriculture, it can be used to synthesize new pesticides or plant growth regulators. With its chemical activity, it can inhibit crop diseases and pests, or regulate plant growth and development process to improve crop yield and quality.
    In the field of scientific research, as an important block of organic synthesis, chemists can explore novel chemical reaction paths and compound structures by modifying and derivatizing their structures, providing assistance for the development of organic chemistry theory and the creation of new compounds.
    What are the synthetic methods of 2-methyl-1H-benzimidazole-5-carboxylic acid?
    The synthesis method of 2-methyl-1H-benzimidazole-5-carboxylic acid, as mentioned in the ancient books, has various paths. First, it can be followed by a suitable starting material and initiated by a condensation reaction. For example, a compound containing a benzene ring with a specific substituent is selected, and a nitrogen-containing heterocyclic precursor is condensed with an acid or base as a catalyst under suitable reaction conditions, such as in a specific solvent, to build the basic structure of benzimidazole.
    Next, the introduction of the carboxyl group of the target product can be achieved by a suitable carboxylation reaction. Or make the preliminarily synthesized benzimidazole derivatives react with reagents that can provide carboxyl groups, such as carbon dioxide, under specific metal catalysts and basic conditions, so it is expected to introduce carboxyl groups at specific positions of benzimidazole to generate 2-methyl-1H-benzimidazole-5-carboxylic acid.
    Furthermore, there are also methods of conversion through multi-step reactions with other similar structural compounds as the starting point. First, the starting material is modified by functional groups, and the desired substituent mode is gradually constructed by halogenation, alkylation and other reactions. Then, the benzimidazole ring is formed by cyclization reaction, and then the carboxylation operation can also achieve the synthesis goal. All methods need to consider the precise control of reaction conditions, such as temperature, reaction time, and proportion of reactants, in order to make the synthesis path efficient and the yield is considerable.
    What is the price range of 2-methyl-1H-benzimidazole-5-carboxylic acid in the market?
    The price of 2-methyl-1H-benzimidazole-5-carboxylic acid is difficult to determine in the market. The price of this compound often varies for many reasons. First, the simplicity of its production, the price of the raw materials used, and the situation of supply and demand are all the most important reasons. If the production process is complicated and rare raw materials are required, the price will be high; if the supply exceeds the demand in the market, the price may decline; if the supply exceeds the demand, the price may rise.
    Furthermore, its purity also has a great impact on the price. High purity 2-methyl-1H-benzimidazole-5-carboxylic acid is often required for scientific research and other fields, and its price is higher than that of ordinary purity.
    Also, the amount purchased is also related to the price. If purchased in bulk, merchants may give discounts due to large quantities, resulting in lower unit prices; if only a small amount is purchased, the unit price may be higher.
    And different places and different suppliers have different prices. Therefore, in order to determine the price of the domain, it is necessary to carefully observe the market situation and consult different suppliers to obtain a more accurate price. However, with the current situation, it is difficult to determine the exact price.
    What are the storage conditions for 2-methyl-1H-benzimidazole-5-carboxylic acid?
    2-Methyl-1H-benzimidazole-5-carboxylic acid, this is a fine chemical, and its storage conditions are quite important. This product should be placed in a cool, dry and well-ventilated place. Because of the cool environment, it can avoid the change of its properties caused by high temperature. In a dry place, it can prevent moisture from causing deliquescence and other conditions to maintain its chemical stability. Well ventilated, it can disperse harmful gases that may be generated and maintain the safety of the storage environment.
    Furthermore, it should be stored separately from oxidants, acids, bases and other substances. This is due to its active chemical properties, coexisting with oxidants, or causing violent oxidation reactions, causing the risk of combustion or even explosion; contact with acid and alkali, or chemical reaction, changing its chemical structure, damaging its quality and efficiency.
    Storage containers should also be carefully selected, and containers with good sealing performance should be used to prevent them from interacting with components in the air, such as oxygen and water vapor. And the storage area should be equipped with suitable materials to deal with possible leakage conditions. In this way, 2-methyl-1H-benzimidazole-5-carboxylic acid can be properly stored to ensure its quality and safety.