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What are the main uses of 2-Mercapto-5-methoxyimidazole- [4,5-b] pyridine?
2-Mercapto-5-methoxyimidazolo [4,5-b] pyridine is a chemical substance. It has a wide range of uses and is often a key intermediate in the synthesis of many biologically active compounds.
In drug development, compounds constructed on this basis may have pharmacological activities such as antibacterial, antiviral, and antitumor. Due to its unique molecular structure, it can interact with specific targets in organisms, or affect cell metabolism and signal transduction pathways, thus demonstrating the potential of treating diseases.
In the field of materials science, it may also have its application. Or it can be chemically modified to have specific photoelectric properties, which can be used in the preparation of organic Light Emitting Diodes, solar cells and other materials. By adjusting its structure, the electrical and optical properties of the materials can be optimized.
In the field of organic synthetic chemistry, 2-mercapto-5-methoxy imidazolo [4,5-b] pyridine can be used as an important synthetic building block to participate in the construction of complex organic molecules. Chemists can use various chemical reactions, such as nucleophilic substitution, cyclization reactions, etc., to derive organic compounds with diverse structures, expand the boundaries of organic synthesis, and provide more possibilities for the creation of new functional materials and drugs.
What are the synthesis methods of 2-Mercapto-5-methoxyimidazole- [4,5-b] pyridine
The synthesis method of 2-mercapto-5-methoxyimidazolo [4,5-b] pyridine has been known since ancient times, and there are many kinds and ingenious ones.
First, pyridine derivatives are used as starting materials and can be obtained through multi-step reactions. First, take a suitable pyridine compound, put it in a specific solvent, use a suitable base as a catalyst, and substitution reaction with methoxy-containing reagents to introduce methoxy groups. This process requires precise control of the reaction temperature and time. If the temperature is too high, side reactions will occur, and if it is too low, the reaction will be delayed. After the methoxy group is successfully connected, the imidazole ring structure is introduced by special means. Usually, the imidazole fragment-containing reagents are used to carry out condensation reaction under appropriate conditions to construct the imidazolo [4,5-b] pyridine skeleton. Finally, through specific reagents and conditions, the thiol group is introduced at the appropriate position to prepare the target product.
Second, starting from imidazole compounds. The imidazole is modified first, and the methoxy group is connected in a suitable way to form an imidazole derivative with methoxy group. Subsequently, this derivative is reacted with pyridine-related reagents in a specific reaction system. The system needs to consider factors such as solvent, ratio of reactants, and pH of the reaction environment. After careful regulation, the two react to gradually build the structure of the pyridine moiety and imidazole parallel ring. In the last step, the thiol group is introduced through a specific chemical reaction to achieve the synthesis of 2-mercapto-5-methoxyimidazolo [4,5-b] pyridine.
Third, there is a multi-step aggregation synthesis strategy with simple small molecules as the starting material. First, the methoxy fragment, the imidazole fragment and the pyridine fragment are constructed respectively, and then the fragments are connected in sequence through ingenious reaction conditions and connection methods. Although this method is complicated, it can precisely control the structure of each part, and the raw materials are easy to obtain, the cost is relatively controllable, which is quite advantageous in large-scale preparation. During the synthesis process, each step of the reaction requires delicate operation and strict reaction conditions to ensure the purity and yield of the target product.
What are the physicochemical properties of 2-Mercapto-5-methoxyimidazole- [4,5-b] pyridine?
2-Mercapto-5-methoxyimidazolo [4,5-b] pyridine is a kind of organic compound. Its physical and chemical properties are particularly important, related to its application in various fields.
In terms of its physical properties, at room temperature, this compound may be in a solid state. As for the exact melting point, it often depends on its purity and crystalline form. If its structure is regular and its purity is quite high, the melting point is relatively fixed and clear. Its appearance may be white to light yellow powder, depending on the synthesis process and the amount of impurities. The solubility of this substance in water is poor, and its molecular structure is mostly hydrophobic groups, while hydrophilic groups are few. However, in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), it has good solubility, which facilitates its operation and application in organic synthesis reactions.
In terms of chemical properties, the sulfhydryl group (-SH) in the molecule of 2-mercapto-5-methoxyimidazolo [4,5-b] pyridine has high reactivity. The sulfhydryl group is easily oxidized and can react with many oxidants to form disulfide bonds (-S-S -). This property can be used in protein chemistry and some pharmaceutical synthesis to construct specific molecular structures. In addition, the heterocyclic structure of imidazolopyridine gives it a certain alkalinity, which can neutralize with acids to form corresponding salts. The heterocyclic ring is also a region with high electron cloud density, prone to electrophilic substitution reactions, such as halogenation reactions, nitrification reactions, etc., which helps to modify its structure to develop derivatives with different properties for use in drug development, materials science and other fields. At the same time, methoxy (-OCH), as a donor group, can affect the electron cloud distribution of molecules, which in turn affects their reactivity and chemical stability.
What is the price range of 2-Mercapto-5-methoxyimidazole- [4,5-b] pyridine in the market?
I look at your question, but I am inquiring about the price range of 2 - Mercapto - 5 - methoxyimidazole - [4,5 - b] pyridine in the market. However, the market valence of this compound often varies with the quality, source and quantity, and it is difficult to determine.
If its quality is good and the supply is thin, and the quantity is small, the price will be high; if the quality is average and the supply is wide, and the quantity is large, the price may be slightly lower. Today's market situation is complex and changeable. To know the details, you need to visit various chemical raw material suppliers and reagent suppliers. Because they are often involved in this industry, they must know the price changes.
Or you can go online, check the chemical trading platform, and observe the prices quoted by various companies to take the average value, or you can get an approximate price range. But this is not a fixed number and is for reference only. If you really want to buy this item, negotiate with the merchant to determine the price.
What are the application fields of 2-Mercapto-5-methoxyimidazole- [4,5-b] pyridine
2-Mercapto-5-methoxyimidazolo [4,5-b] pyridine is a unique organic compound. It has considerable use in various fields.
In the field of medicinal chemistry, this compound is often the key raw material for the creation of new drugs. Due to its unique chemical structure, it can be combined with specific targets in organisms, or it can exhibit significant pharmacological activity. For example, it can be used to develop drugs with antiviral, antitumor, antibacterial and other effects. Drug developers often take advantage of the properties of this compound and use clever molecular design and modification to develop new drugs with excellent efficacy and mild side effects.
In the field of materials science, 2-mercapto-5-methoxyimidazolo [4,5-b] pyridine also has its uses. It can participate in the synthesis process of specific materials, giving materials unique properties. It can improve the stability, conductivity, or improve its optical properties of materials, and has great potential in the preparation of new functional materials, such as photoelectric materials, sensor materials, etc.
Furthermore, in the field of organic synthesis chemistry, this compound is often used as an intermediate in organic synthesis. Due to its special structure, it can combine with other organic molecules through various chemical reactions to form more complex organic compounds, which can help organic chemists expand the synthesis path, prepare organic products with diverse structures and functions, and promote the development of organic synthetic chemistry.
In summary, 2-mercapto-5-methoxyimidazolo [4,5-b] pyridine plays an important role in many fields such as medicine, materials, and organic synthesis, providing strong support for progress and innovation in related fields.