Chemical Formula | C8H8N2OS |
Molar Mass | 180.23 g/mol |
Appearance | White to off - white powder |
Melting Point | 178 - 182 °C |
Solubility In Water | Poorly soluble |
Solubility In Organic Solvents | Soluble in some organic solvents like DMSO, DMF |
Pka Value | Around 6.5 (approximate, related to the acidic hydrogen of the mercapto group) |
Density | N/A (no common data available for density) |
Stability | Stable under normal conditions, but may react with strong oxidizing agents |
Odor | Faint, characteristic odor |
What are the main uses of 2-Mercapto-5-methoxybenzimidazole (MMBD)?
2-Mercapto-5-methoxybenzimidazole (MMBD) is widely used in chemical and pharmaceutical fields.
In the chemical industry, it is often used as a rubber auxiliary. The structure of sulfhydryl and benzimidazole can improve the vulcanization process of rubber and improve the physical properties of rubber. In the vulcanization system, it can be used as an accelerator to accelerate the vulcanization speed, improve the degree of crosslinking, and make rubber products better tensile strength, wear resistance and aging resistance. For example, in the manufacture of automobile tires, adding an appropriate amount of MMBD can make the tires more wear-resistant, prolong the service life, and maintain their stable performance under different road conditions.
As for the field of medicine, MMBD exhibits significant biological activity. Studies have shown that it has certain antibacterial and antiviral effects. Due to its structural characteristics, it can combine with key targets in microorganisms and interfere with their metabolism and reproduction. For example, targeting some Gram-positive and negative bacteria, MMBD can inhibit their growth. In addition, in the field of anti-tumor drug development, MMBD has also attracted attention. Studies have shown that it may induce tumor cell apoptosis, inhibit tumor cell proliferation by affecting tumor cell signaling pathways, and provide a new direction for the creation of anti-cancer drugs.
In summary, 2-mercapto-5-methoxybenzimidazole (MMBD) has important uses in the rubber manufacturing of chemical industry, as well as the research and development of antibacterial and anti-tumor in medicine, and occupies a key position in the development of modern industry and medicine.
What are the physical properties of 2-Mercapto-5-methoxybenzimidazole (MMBD)?
The physical properties of 2-mercapto-5-methoxybenzimidazole (MMBD) are quite impressive. At room temperature, this substance is mostly in the form of a solid state. Looking at its color, it is usually white to light yellow powder, with a warm color, like heaven. Its texture is delicate, and it feels soft to the touch, just like the accumulation of fine dust.
When it comes to solubility, the solubility of MMBD in water is quite low, due to its molecular structure. However, in some organic solvents, it can show good solubility. For example, in polar organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), it can be dissolved relatively smoothly. This property makes it convenient to select an appropriate solvent system in many chemical synthesis and experimental operations to promote the development of related reactions. The melting point of
MMBD is also one of its important physical properties. After fine determination, its melting point is in a specific temperature range. This melting point data provides a key reference for relevant researchers to identify and purify the substance. Accurate control of temperature conditions is crucial for obtaining high-purity MMBD.
In addition, the stability of MMBD cannot be ignored. Under normal environmental conditions, its chemical properties are relatively stable and can maintain its own structure and properties constant for a certain period of time. However, when encountering special conditions such as specific chemical reagents, high temperature or strong light exposure, its structure may change accordingly, which in turn affects its properties and functions. Therefore, when storing and using MMBD, it is necessary to fully consider the influence of external factors to ensure its intact performance.
What are the chemical properties of 2-Mercapto-5-methoxybenzimidazole (MMBD)?
2-Mercapto-5-methoxybenzimidazole (MMBD) has many unique chemical properties. In its structure, the benzimidazole ring endows it with certain aromatic stability. The methoxy group is attached to the benzene ring, and the electron cloud density of the benzene ring can be increased due to the methoxy group as the power supply group, which affects the electron distribution and reactivity of the molecule. In the electrophilic substitution reaction, the adjacent and para-sites of the methoxy group are more susceptible to attack by electrophilic reagents.
Furthermore, the presence of thiol groups adds another activity to the compound. The sulfur atom in the thiol group has a lone pair of electrons, so that MMBD can be used as a ligand to coordinate with metal ions to form a stable complex. This property may have applications in the field of metal ion detection and catalysis. And the thiol group is easily oxidized and can participate in the redox reaction. Under appropriate conditions, it can be converted into oxidation products such as disulfide bonds. This property has potential significance in organic synthesis and biochemical processes.
In addition, MMBD has a certain acidity and alkalinity due to the presence of benzimidazole rings and substituents. In different acid-base environments, the molecular structure or charge distribution will change, which will affect its solubility, stability and reactivity. In short, 2-mercapto-5-methoxybenzimidazole has a variety of chemical properties derived from its special structure, which has potential applications in many fields.
What is the preparation method of 2-Mercapto-5-methoxybenzimidazole (MMBD)?
The preparation method of 2-mercapto-5-methoxybenzimidazole (MMBD) is a very important chemical process. In the past, the preparation of this compound followed a specific chemical path.
First, it is often started with suitable starting materials, such as benzene ring derivatives containing methoxy groups and specific substituents. In the reaction system, the reaction reagents and conditions are carefully prepared. Generally speaking, a suitable catalyst is required to promote the smooth progress of the reaction. The choice of this catalyst depends on the reaction rate and yield.
In terms of reaction conditions, the control of temperature and reaction time is crucial. If the temperature is too high or too low, it may affect the reaction process, causing the product to be impure or the yield to be low. Usually, the reaction temperature needs to be maintained at a specific range and the reaction takes several hours to fully convert the reactants.
Furthermore, the choice of solvent in the reaction process should not be underestimated. Suitable solvents can effectively dissolve the reactants and help them mix evenly, thereby improving the reaction efficiency.
After the reaction is completed, a series of separation and purification steps are required. This process may involve filtration, extraction, crystallization and other means to obtain high-purity 2-mercapto-5-methoxybenzimidazole. Each step requires fine operation to obtain satisfactory products. As such, it is a common method for preparing 2-mercapto-5-methoxybenzimidazole.
2-Mercapto-5-methoxybenzimidazole (MMBD) What are the precautions during use
2-Mercapto-5-methoxybenzimidazole (MMBD) is a special chemical substance. During use, several terminals must be paid attention to.
First, it is related to safety protection. This substance may be toxic and irritating. When exposed, be sure to wear suitable protective equipment, such as gloves, goggles, gas masks, etc., to avoid contact with the skin, eyes and respiratory tract. If you come into contact inadvertently, rinse with plenty of water immediately and seek medical assistance according to the specific situation.
Second, storage conditions are very critical. Keep it in a cool, dry and well-ventilated place, away from fire sources and oxidants. Due to its active chemical nature, improper storage or deterioration can even cause safety accidents.
Third, the use operation should be accurate and standardized. Before use, you should be familiar with its chemical properties and reaction characteristics, and operate in strict accordance with experimental procedures or production requirements. Weighing, dissolving and other steps must be accurate to prevent improper operation from causing abnormal reactions or low yield.
Fourth, waste treatment should not be ignored. After use, waste containing MMBD should be properly disposed of in accordance with relevant regulations and should not be discarded at will to avoid polluting the environment. Appropriate treatment methods, such as chemical neutralization, incineration or deep burial, should be selected according to their characteristics, and ensure that the treatment process meets environmental protection standards.
In summary, when using 2-mercapto-5-methoxybenzimidazole, all aspects of safety protection, storage conditions, operating practices, and waste disposal need to be treated with caution to ensure that the use process is safe and compliant.