2-Mercapto-5-(1-Pyrrolyl)Benzimidazole

2-Mercapto-5- (1-pyrrolyl) benzimidazole, which is used in many fields. In the field of medicine, it is often used as a key intermediate in drug synthesis because of its unique chemical structure and biological activity. It can participate in specific chemical reactions to build complex drug molecular structures, which is of great significance for the development of antibacterial, antiviral and anti-tumor drugs. For example, it can be cleverly combined with other active groups to precisely act on specific targets of pathogens or tumor cells, and exert therapeutic effects.
In the field of materials science, it also shows unique properties. It can be integrated into polymer materials as a functional additive to improve material stability and oxidation resistance. Adding an appropriate amount of this compound to the preparation of plastics, rubber and other materials can effectively delay the aging process of materials and prolong the service life. Because of its sulfhydryl group can react with some groups on the surface of the material to form stable chemical bonds and build an anti-oxidation protective layer.
In the field of chemical analysis, 2-mercapto-5- (1-pyrrolyl) benzimidazole can act as an analytical reagent. With its selective complexation characteristics with specific metal ions, sensitive detection and accurate quantitative analysis of metal ions can be achieved. In environmental monitoring, it is crucial to determine the content of specific metal ions in water and soil samples, providing key data for environmental quality assessment.

To prepare 2-mercapto-5- (1-pyrrolyl) benzimidazole, there are many methods, and the following are various synthesis methods.
First, the compound containing pyrrole group and the precursor containing mercapto group and benzimidazole structure can be made to undergo a specific reaction by organic synthesis under suitable reaction conditions to form the target product. For example, select a suitable pyrrole derivative, make it with the benzimidazole precursor with a specific substituent, with the help of a catalyst, heat and stir in a specific solvent, and after several reaction steps such as nucleophilic substitution, it is expected to be obtained.
Second, a series of step-by-step reaction strategies can be designed. First construct the basic skeleton of benzimidazole, then introduce a sulfhydryl group at a suitable check point, and then try to connect a 1-pyrrole group. In this way, the reaction conditions can be precisely controlled according to the characteristics of each step of the reaction to improve the purity and yield of the product. For example, when synthesizing the benzimidazole skeleton in the first step, adjust the reaction temperature, the proportion of reactants and other parameters to make the reaction proceed in the desired direction; introduce a sulfhydryl group step, select the appropriate sulfhydration reagent, and control the reaction time and pH; when connecting 1-pyrrolide, use a suitable coupling reaction to ensure its accurate connection.
Third, it can also be improved and optimized by referring to the mature methods reported in the literature. The steps of previous synthesis of similar compounds are carefully studied, and the reaction solvent, catalyst, reaction time and other factors are adjusted according to their own experimental conditions and requirements. If the reaction conditions used in some literatures are more harsh, you can try to find milder alternative conditions, or choose new catalysts to simplify the operation process and improve the reaction efficiency, so as to achieve efficient synthesis of 2-mercapto-5- (1-pyrrolyl) benzimidazole.

2-Mercapto-5- (1-pyrrolyl) benzimidazole is an organic compound. Its physical and chemical properties are quite unique, and it is of certain importance in scientific research and chemical industry.
In terms of its physical properties, under normal conditions, this substance is mostly in a solid state, but the specific form may vary depending on the preparation method and purity, or in a crystalline state, or in a powdery state. As for the color, it often appears white to light yellow. Its melting point is also one of the key physical properties. It has been experimentally determined that the melting point is within a certain temperature range. This property can help identify and purify the substance. In terms of solubility, it exhibits a certain solubility in common organic solvents, such as ethanol and dichloromethane, but its solubility in water is relatively low. This difference in solubility provides an important basis for its application in different chemical reaction systems.
When it comes to chemical properties, in the structure of 2-mercapto-5 - (1-pyrrolyl) benzimidazole, mercapto (-SH) interacts with benzimidazole ring and pyrrolyl group, giving it unique chemical activity. The sulfhydryl group has high reactivity and can participate in many chemical reactions, such as oxidation reactions. Under appropriate oxidation conditions, the sulfhydryl group can be oxidized to disulfide bonds (-S-S -), which is of great significance in the study of the structure and function of proteins and polypeptides. At the same time, benzimidazole ring and pyrrole also enable the substance to participate in nucleophilic substitution, electrophilic substitution and other reactions. Because its structure is rich in nitrogen atoms, it can be used as an electron donor to form coordination compounds with metal ions. This property has potential application value in the detection and catalysis of metal ions.
The physicochemical properties of 2-mercapto-5- (1-pyrrolyl) benzimidazole determine its application prospects in organic synthesis, medicinal chemistry, materials science and other fields. It is an organic compound worthy of further study.

I look at your question, but I am inquiring about the price range of 2 - Mercapto - 5 - (1 - Pyrrolyl) Benzimidazole in the market. However, the price of this chemical substance varies for many reasons.
First, its purity is crucial. If the purity is extremely high, it is almost flawless, and the price must be high; if it contains impurities, the price should drop. Furthermore, the market supply and demand trend also affects its price. If there are many people who want it, and there are few people who supply it, the price will rise; if the supply exceeds the demand, the price will fall.
Also, the difficulty of preparation also affects. If the preparation requires complicated methods and requires a lot of materials and effort, the price will be high; if the preparation is simple, the price will be low. And the price varies depending on the seller. Large merchants may have an advantage due to the benefit of scale; small merchants may have a slightly higher price due to cost.
However, I checked the classics all over, but I couldn't get a definite number. Today's market is changing, and it is difficult to make a rule. It is possible to count gold per gram, or tens of gold per gram. To know the exact price, you need to consult the chemical market merchants, or check the records of recent transactions, to get a rough estimate.

The manufacturer of 2-mercapto-5- (1-pyrrolyl) benzimidazole, through the ages, there have been many chemical creators in the world, but those who are proficient in this product need to be carefully investigated.
In today's world, there are many chemical leaders in China involved in the production of this product. Among them, there is a factory famous for fine chemicals, whose skills are exquisite, and they control all kinds of chemical synthesis. The synthesis process of 2-mercapto-5- (1-pyrrolyl) benzimidazole has been studied and improved for many years. With advanced equipment and strict quality control, the factory produces high-quality products and has a good reputation in the industry.
There are also companies that focus on the research and development of new materials. They have a long-term perspective, insight into the potential uses of 2-mercapto-5- (1-pyrrolyl) benzimidazole in the field of new materials, and invest a lot of manpower and material resources in production and innovation. Its production process focuses on green environmental protection, and strives to produce high-quality products while taking into account the protection of the ecological environment.
There are also many such manufacturers in overseas countries. There are established chemical enterprises in Europe and the United States, with a long history and profound technical background. In the production of 2-mercapto-5- (1-pyrrolyl) benzimidazole, following strict international standards, the products are sold all over the world, providing a stable supply for the global chemical market.
Another chemical enterprise in Japan and South Korea, with its rigorous attitude and innovative spirit, is unique in the production of this product. It pays attention to the refinement and differentiation of products, and constantly introduces new ones to meet the needs of market diversification.
All of these manufacturers, whether specialized in technology, innovative, or environmentally friendly, contribute to the production of 2-mercapto-5- (1-pyrrolidino) benzimidazole and jointly promote the development of this field.