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What is the chemical structure of 2-Ethoxy-3- [[4- [2- (1H-tetrazol-5-yl) phenyl] phenyl] methyl] -3H-benzoimidazole-4-carboxylic acid (C8)?
This is a description of an organic compound, which is named 2-ethoxy-3- [4- [2- (1H-tetrazolyl-5-yl) phenyl] phenyl] methyl] -3H-benzimidazole-4-carboxylic acid (C8). To clarify its chemical structure, let me tell you in detail.
Looking at its name, it can be seen that this compound contains multiple parts. "2-ethoxy" indicates that there is an ethoxy group attached to the No. 2 position of the benzimidazole ring. This ethoxy group is composed of ethyl and oxygen atoms. Ethyl is a group obtained by removing a hydrogen atom from ethane.
"3- [4- [2- (1H-tetrazolyl-5-yl) phenyl] phenyl] methyl]", this part reveals that at position 3 of the benzimidazole ring, a complex side chain is connected. This side chain is first a methylene (-CH ² -), and the methylene is then connected to a structure composed of two phenyl groups, in which position 4 of one phenyl is connected to another phenyl group, and position 2 of this phenyl is connected to 1H-tetrazolyl-5-group. The 1H-tetrazole-5-group is composed of a five-membered ring with four nitrogen atoms and one hydrogen atom in the ring, and is connected to the phenyl group at position 5.
"3H-benzimidazole-4-carboxylic acid", indicating that the compound has benzimidazole as the core structure, and benzimidazole is formed by fusing the benzene ring with the imidazole ring. The benzimidazole ring has the complex side chain mentioned above at position 3, and the carboxyl group (-COOH) at position 4, which is the functional group of the carboxylic acid.
In summary, the chemical structure of 2-ethoxy-3- [4- [2- (1H-tetrazole-5-yl) phenyl] phenyl] methyl] -3H-benzimidazole-4-carboxylic acid (C8) is composed of a benzimidazole ring with an ethoxy group at position 2, a complex side chain at position 3, and a carboxyl group at position 4. This structure determines its chemical properties and possible reactions, and is an important basis for organic chemistry research.
What are the main uses of 2-Ethoxy-3- [[4- [2- (1H-tetrazol-5-yl) phenyl] phenyl] methyl] -3H-benzoimidazole-4-carboxylic acid (C8)?
2-Ethoxy-3- [[4- [2- (1H-tetrazolium-5-yl) phenyl] phenyl] methyl] -3H-benzimidazole-4-carboxylic acid (C8), which has a wide range of uses.
In the development of medicine, it can be a key raw material for the creation of new anti-hypertensive drugs. The tetrazole group and benzimidazole structure can play a unique role in the regulation of blood pressure. The tetrazole group may mimic the biological activity of the carboxyl group and interact with the angiotensin ⅱ receptor to block its signal conduction, then dilate the blood vessels and lower the blood pressure. The structure of benzimidazole may also participate in the regulation of certain enzyme activities, helping to maintain the homeostasis of the cardiovascular system.
In the field of materials science, it may have the potential to become a special functional material. Due to its complex and unique molecular structure, it may endow materials with specific optical and electrical properties. For example, in the field of organic optoelectronic materials, the structure of such compounds can be cleverly designed to achieve precise regulation of light absorption and emission characteristics, and can be used to prepare high-efficiency Light Emitting Diodes or solar cell materials.
In the field of agricultural chemistry, it may be developed as a new type of pesticide. Its special structure may have specific biological activities against certain crop pests or pathogens. By modifying and optimizing its structure, it is expected to create high-efficiency, low-toxicity and environmentally friendly pesticides, which can not only effectively control pests and diseases, but also reduce the adverse impact on the ecological environment.
Furthermore, in the field of chemical research, as a special class of organic compounds, it provides an excellent research object for organic synthetic chemistry. Chemists can use various chemical reactions to explore novel synthetic methods and strategies, improve the understanding of organic reaction mechanisms, and promote the development of organic synthetic chemistry.
What are the physical properties of 2-Ethoxy-3- [[4- [2- (1H-tetrazol-5-yl) phenyl] phenyl] methyl] -3H-benzoimidazole-4-carboxylic acid (C8)?
2-Ethoxy-3- [[4- [2- (1H-tetrazolium-5-yl) phenyl] phenyl] methyl] -3H-benzimidazole-4-carboxylic acid (C8), this physical property is particularly important, related to its use and characteristics.
Looking at its properties, at room temperature, or solid, as for its color, or white, off-white powder, or crystalline, this form is easy to store and use. Its melting point is also a key physical property. The melting point is determined by the intermolecular force. When the temperature rises to a certain value, the molecule is energized enough to break free from the lattice and convert from solid to liquid. The boiling point is related to the critical temperature of liquid to gas, which has a great impact on its phase change under different conditions.
Solubility is also an important physical property. In water and organic solvents, the solubility varies. In water, or because of the different degree of interaction between molecular polarity and water molecules, the solubility may be limited; in organic solvents such as ethanol and dichloromethane, due to the similar principle of dissolution, or different dissolution effects, this property affects its dispersion and mass transfer in preparation, separation and reaction systems. < Br >
In terms of stability, under general environmental conditions, if it is not affected by extreme factors such as light, high temperature, and high humidity, the structure may remain relatively stable. In case of strong acid, strong base, or specific redox conditions, some bonds in its molecular structure may be affected, resulting in chemical reactions, resulting in changes in its structure and properties.
Density is also one of its physical properties. Although it is not often the focus of attention, it is affected by density differences in specific application scenarios, such as in liquid-liquid separation and mixing systems.
The many physical properties of this 2-ethoxy-3- [4- [2- (1H-tetrazolium-5-yl) phenyl] phenyl] -3H-benzimidazole-4-carboxylic acid (C8) are related to each other and together determine its application and performance in the fields of chemistry, medicine and so on.
What is the synthesis method of 2-Ethoxy-3- [[4- [2- (1H-tetrazol-5-yl) phenyl] phenyl] methyl] -3H-benzoimidazole-4-carboxylic acid (C8)?
To prepare 2-ethoxy-3- [[4- [2- (1H-tetrazolium-5-yl) phenyl] phenyl] methyl] -3H-benzimidazole-4-carboxylic acid (C8), the synthesis method is as follows.
First take appropriate starting materials, such as benzimidazole derivatives containing ethoxy groups, and benzene ring compounds with specific substituents, and the structures of the two are partially compatible with the target product. Dissolve in suitable organic solvents, such as dichloromethane or N, N-dimethylformamide, to form a uniform solution system. < Br >
Add an appropriate amount of catalyst at times, depending on the reaction mechanism, either metal catalysts such as palladium, or acid or alkali catalysts. At an appropriate temperature, or at room temperature, or heated to a certain extent to promote the reaction. A condensation reaction occurs between the starting materials, forming key carbon-carbon bonds, and gradually forming the basic structure of the product.
After the initial reaction is completed, the reaction mixture needs to be treated. Or by extraction, with a suitable extractant, the organic phase is separated from the aqueous phase to remove impurities. The product is further purified by column chromatography or recrystallization. During column chromatography, appropriate silica gel and eluent are selected to effectively separate the product from impurities; for recrystallization, a solvent with suitable solubility of the product is selected to cool down and crystallize to obtain a pure product.
In addition, during the reaction process, the reaction process should be closely monitored, and the degree of reaction can be determined by means of thin layer chromatography, high performance liquid chromatography, etc., and the reaction conditions can be adjusted in a timely manner to achieve the best synthetic effect. High purity of 2-ethoxy-3- [4- [2- (1H-tetrazolium-5-yl) phenyl] phenyl] methyl] -3H-benzimidazole-4-carboxylic acid (C8).
What are the safety precautions for 2-Ethoxy-3- [[4- [2- (1H-tetrazol-5-yl) phenyl] phenyl] methyl] -3H-benzoimidazole-4-carboxylic acid (C8)?
2-Ethoxy-3- [[4- [2- (1H-tetrazolium-5-yl) phenyl] phenyl] methyl] -3H-benzimidazole-4-carboxylic acid (C8) is a complex chemical substance. Regarding its safety precautions, it is extremely important, so let me elaborate.
Bear the brunt, and the properties and reactions of chemical substances need to be paid attention to in detail. This compound has a complex structure or has specific chemical activities. During operation, be sure to avoid contact with strong oxidants, strong acids, strong bases and other substances. Due to strong oxidizing agents or severe oxidation reactions, strong acids, strong bases or compounds decompose, and even cause dangerous chemical reactions, such as the generation of toxic gases, explosions and other serious consequences.
Furthermore, its toxicity cannot be ignored. Although the details of its toxicity are not known exactly, it should still be assumed that it is potentially toxic when operating. Therefore, operators must wear complete protective equipment, such as laboratory clothes, protective gloves, protective glasses, etc. If they accidentally touch the skin, they should immediately rinse with plenty of water. If it enters the eyes, they should immediately rinse with flowing water and seek medical attention. If accidentally inhaled, they should quickly go to a fresh air place. If the symptoms do not subside, they should also seek medical attention.
Storage is also important. Store in a cool, dry and well-ventilated place, away from fire and heat sources. Due to high temperature or unstable compounds, decomposition or other adverse reactions may occur. At the same time, it should be stored separately from other incompatible chemicals to avoid interaction.
In addition, in the experimental site, first aid equipment, eye washers, emergency spray devices, etc. should be readily available and ensure normal use. Operators should also be familiar with emergency handling procedures. In the event of an accident, they can respond quickly and properly. In this way, the safety of personnel and the smooth progress of the experiment can be guaranteed to the greatest extent.