2-Cyclopropyl-1H-imidazole

2-Cyclopropyl-1H-imidazole is also an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. Due to its unique structure, it can be chemically synthesized to react with other compounds to obtain biologically active drug molecules. It is important for the development of antibacterial, anti-inflammatory, anti-tumor and other drugs.
In the field of materials science, 2-cyclopropyl-1H-imidazole also shows its value. It can be used as a ligand and complexed with metal ions to prepare metal-organic framework materials (MOFs). These materials have the characteristics of high specific surface area and regular pore structure, and have excellent performance in gas adsorption, separation and catalysis.
Furthermore, in the field of organic synthesis chemistry, 2-cyclopropyl-1H-imidazole can participate in many chemical reactions, such as nucleophilic substitution, cyclization, etc. By ingeniously designing the reaction path, complex and novel organic compounds can be synthesized, which contributes to the development of organic synthesis chemistry. Its application in the above fields depends on its own unique chemical structure and reactivity, providing assistance for progress in many fields.

The synthesis method of Fu2-cyclopropyl-1H-imidazole has been studied in the past. One method is to use cyclopropyl carboxylic acid as the starting material and obtain it through multi-step conversion. First, cyclopropyl carboxylic acid is reacted with sulfuryl chloride to obtain cyclopropanoyl chloride. In this step, the reaction temperature and the proportion of the material should be paid attention to to to prevent side reactions. Cyclopropanoyl chloride is then condensed with suitable amines to form amide intermediates. Then this intermediate is dehydrated and cyclized. Dehydrating agents such as phosphorus pentoxide are commonly used. In this process, the control of reaction conditions is crucial, and temperature and time will affect the yield and purity of the product. < Br >
There are also those who use cyclopropyl acetonitrile as the starting material. Cyclopropyl acetonitrile is first reacted with a specific reagent, a nitrogen-containing group is introduced, and it is converted into the corresponding carboxylic acid derivative through hydrolysis and other steps. Then, the imidazole ring structure is constructed through the internal cyclization reaction. In this route, the hydrolysis step needs to select suitable acid and base conditions to ensure the smooth progress of the reaction, and the cyclization step also needs to carefully select the catalyst and reaction environment to promote the reaction to generate the target product.
Another one uses halogenated hydrocarbons and imidazole salts containing cyclopropyl groups as raw materials. In a suitable solvent, the nucleophilic substitution reaction occurs under the action of a base. In this process, the polarity of the solvent, the strength and dosage of the base all affect the reaction process and the yield of the product. It is necessary to carefully optimize the reaction parameters in order to improve the production efficiency and quality of the target product 2-cyclopropyl-1H-imidazole.

2-Cyclopropyl-1H-imidazole, this is an organic compound with unique physical and chemical properties.
Its appearance is often white to off-white crystalline powder, which makes it easy to disperse and participate in reactions in many reaction systems. Looking at its melting point, it is about 150-155 ° C. The melting point characteristics provide a key reference for its heating or melting related operations, which can help determine its phase transition node and facilitate accurate control of reaction conditions.
In terms of solubility, it is slightly soluble in water, but soluble in common organic solvents, such as dichloromethane, ethanol, acetone, etc. The property of being slightly soluble in water makes it difficult to dissolve and disperse in the aqueous phase system; while it is soluble in organic solvents, so that it can use suitable organic solvents as the reaction medium in the field of organic synthesis to promote the reaction.
In terms of chemical properties, the imidazole ring in 2-cyclopropyl-1H-imidazole contains an electron-rich system, which endows it with significant nucleophilicity. Because the nitrogen atom on the imidazole ring has lone pair electrons, it is easy to react with electrophilic reagents, such as alkylation and acylation reactions. Taking the alkylation reaction as an example, under suitable basic conditions and the action of catalysts, the lone pair electrons of the nitrogen atom can attack alkylation reagents such as haloalkanes to generate alkylation products.
In addition, 2-cyclopropyl-1H-imidazole cyclopropyl also has special reactivity. Cyclopropyl has high ring tension, is relatively unstable, and is easy to open the ring under specific conditions, providing novel reaction pathways and product structures for organic synthesis. This unique structure and reactivity make 2-cyclopropyl-1H-imidazole attract much attention in the fields of medicinal chemistry and materials science. It is often used as a key intermediate to construct complex organic molecular structures and promote the development of related fields.

Today there is 2-cyclopropyl-1H-imidazole, and you want to know its price on the market. This is a fine chemical, and its price often varies depending on purity, order of magnitude, and supply and demand.
If you want a small quantity, low purity product, or for laboratory research, at a chemical reagent supplier, the price per gram may be in the tens of yuan. However, if its purity is high, it reaches the standard of pharmaceutical grade or higher, and the dosage is slightly larger, such as the order of hundreds of grams to kilograms, the price will be different.
When the purity is high and the quantity is large, the price per gram may be reduced to a few yuan to a dozen yuan due to economies of scale. However, this is only an approximation, and the actual price depends on the supplier, the time of purchase, etc. If the raw materials are scarce and the demand increases greatly, the price may rise; if the raw materials are abundant and the market competition is fierce, the price may decline.
As for the exact price, you must consult all chemical raw material suppliers, or check it in detail on the chemical product trading platform to get the exact number. Its price fluctuates constantly, and you need to inquire in real time to know the current real price.

2-Cyclopropyl-1H-imidazole is one of the organic compounds. I have not visited the workshop in the world today, but I know a thing or two.
In the land of China, there are many manufacturers who are skilled in organic synthesis, or involved in the production of this product. For example, some enterprises that focus on fine chemicals have exquisite skills and well-equipped equipment, and can often synthesize such compounds. They manage all matters of production with scientific methods and rigorous attitude.
I also heard that there are several overseas manufacturers involved. In Western countries, the chemical industry has a deep foundation and has made great achievements in the field of organic synthesis. Its research and development power is strong, and the production process may be more perfect.
If you want to know the detailed list of manufacturers, you need to search for chemical classics, industry records, or visit chemical markets, business offices, and consult experts before you can get the details. Or consult current chemical journals and online information, which may have factory advertisements and product directories, and carefully identify them, or find manufacturers that produce 2-cyclopropyl-1H-imidazole.