2 Chloromethyl 6 Fluoro 1h Benzo D Imidazole
quinoline thiophene imidazole thiazole

2-(CHLOROMETHYL)-6-FLUORO-1H-BENZO[D]IMIDAZOLE

    Specifications

    HS Code

    877979

    Chemical Formula C8H6ClFN2
    Molar Mass 184.598 g/mol
    Appearance Solid (likely)
    Melting Point Data may vary, check literature
    Boiling Point Data may vary, check literature
    Solubility In Water Limited solubility expected
    Solubility In Organic Solvents Soluble in common organic solvents
    Density Data may vary, check literature
    Flash Point Data may vary, check literature
    Pka Data may vary, check literature
    Vapor Pressure Data may vary, check literature

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    As a leading 2-(CHLOROMETHYL)-6-FLUORO-1H-BENZO[D]IMIDAZOLE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2- (chloromethyl) -6-fluoro-1H-benzo [d] imidazole?
    The main uses of 2-% (cyanomethyl) -6-cyano-1H-indolo [d] azole are quite extensive. In the field of medicine, it can be used as a key intermediate to create new drugs. Because of its specific chemical structure and activity, the compound can act on certain disease-related targets, helping to develop drugs with more efficacy and lower side effects, such as targeted therapeutic drugs for specific tumor cells, inhibiting tumor cell growth and diffusion by precisely acting on specific proteins or signaling pathways in tumor cells.
    In the field of materials science, it can participate in the synthesis of materials with special photoelectric properties. Its chemical structure endows molecules with unique electron cloud distribution and conjugation system, or can exhibit excellent fluorescence properties, semiconductor properties, etc. Using these properties, functional materials can be prepared for organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices, and the performance indicators such as luminous efficiency and photoelectric conversion efficiency of the devices can be improved.
    In addition, in the field of organic synthetic chemistry, it is also an important synthetic building block. With its multiple activity check points, chemists can use various organic reactions to modify and derive its structure, synthesize more complex and diverse organic compounds, and provide rich raw materials and intermediates for the development of organic synthetic chemistry, promoting the innovation and progress of organic synthesis methodology.
    What are the physical properties of 2- (chloromethyl) -6-fluoro-1H-benzo [d] imidazole
    2-% (cyanomethyl) -6-cyano-1H-indolo [d] -azole, this is an organic compound. Its physical properties are as follows:
    Looking at its appearance, it is often in a solid state, but the specific color state will vary depending on the purity and crystallization conditions, or it is a white to light yellow crystalline powder. Its melting point and boiling point are critical. The melting point determines the temperature of its solid-state and liquid-state transition, and the boiling point is related to the conditions of its liquid-state and gas-state transition. However, the exact value needs to be determined by professional experiments, and different literature reports or vary depending on the experimental methods and conditions.
    In terms of solubility, the compound has significant solubility properties in organic solvents. Generally speaking, it is easily soluble in common organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. This solubility is closely related to its molecular structure. The polar groups in the molecule interact with the non-polar parts, making it exhibit different solubility in polar and non-polar organic solvents. In water, due to its hydrophobic molecular structure, the solubility is relatively low.
    Density is also one of the important physical properties. Although the exact value needs to be determined accurately by experiments, it can be roughly inferred according to its molecular structure and the properties of similar compounds. Its density may be similar to that of common organic solids.
    In addition, the stability of this compound is also a consideration of physical properties. Under normal temperature and pressure, dark and dry environment, it is relatively stable. However, under specific conditions such as high temperature, strong acid, strong base or strong oxidant, the molecular structure may change, triggering a chemical reaction, and the stability will change accordingly.
    Is 2- (chloromethyl) -6-fluoro-1H-benzo [d] imidazole chemically stable?
    2-%28%E6%B0%AF%E7%94%B2%E5%9F%BA%29-6-%E6%B0%9F-1H-%E8%8B%AF%E5%B9%B6%5Bd%5D%E5%92%AA%E5%94%91%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E7%A8%B3%E5%AE%9A%E5%90%97%3F
    This substance is called 2- (methoxy methyl) -6-fluoro-1H-indoleo [d] azole, and its chemical properties are relatively stable. In this substance, the core structure of indoleozole endows it with a certain conjugate stability, and the conjugate system can disperse electrons and enhance molecular stability. The existence of methoxy methyl can stabilize the molecular charge distribution and improve the overall stability due to its electron supply effect. Although the fluorine atom has strong electronegativity, it interacts with surrounding atoms at a specific position in the molecule, does not overly destroy the molecular structure, but stabilizes the electron cloud distribution to a certain extent through its induction effect. Under common chemical reaction conditions, the substance can maintain a relatively stable chemical state without the action of strong oxidizing agents, reducing agents or special catalysts. However, under extreme conditions such as high temperature, high pressure or strong acid and base, some chemical bonds in its structure may be broken or rearranged. For example, in a strongly acidic environment, methoxy methyl may undergo protonation, which may lead to a series of substitution or elimination reactions; at high temperature, the indolazole structure may undergo cyclization and rearrangement reactions. Overall, under normal mild conditions, the chemical properties of 2 - (methoxy methyl) -6-fluoro-1H-indolo [d] azole are relatively stable.
    What are the synthesis methods of 2- (chloromethyl) -6-fluoro-1H-benzo [d] imidazole
    To prepare 2- (methoxy) -6-methyl-1H-indolo [d] pyrimidine, there are many methods, each with its own advantages and disadvantages. The following common methods are described in detail.
    One is to use raw materials containing methoxy groups and methyl groups, through the steps of condensation and cyclization. First take a suitable starting material and make it condensed under specific conditions. The conditions are very critical, such as temperature, solvent and catalyst. After the condensation is completed, the cyclization reaction is carried out, or a specific reagent needs to be introduced to promote the smooth progress of cyclization. During this process, the purity of the raw material and the subtle changes in the reaction conditions can have a significant impact on the yield and purity of the product.
    The second is to modify the parent of indolo [d] pyrimidine. First obtain the structure of indolo [d] pyrimidine, and then introduce methoxy and methyl groups at specific positions. Introducing methoxy groups can choose suitable methoxylating reagents and react under suitable reaction conditions. Similarly, introducing methyl groups also requires selecting the right reagents and conditions. The difficulty of this approach lies in the selective control of the reaction check point to avoid unnecessary side reactions.
    Third, the strategy of gradually constructing the ring system can be adopted. First construct the indole ring part, then try to connect to the pyrimidine ring, and introduce the required methoxy and methyl groups at the same time. Each step of construction requires careful design of the reaction route, considering the stability and reactivity of the intermediate.
    There are various methods for preparing 2- (methoxy) -6-methyl-1H-indolo [d] pyrimidine. In actual operation, it is necessary to comprehensively consider many factors such as experimental conditions, raw material availability and product requirements, and choose the most suitable method to achieve the purpose of efficient and high-purity preparation.
    What is the market price of 2- (chloromethyl) -6-fluoro-1H-benzo [d] imidazole?
    Wen Jun inquired about the price of 2- (methoxy) -6-methyl-1H-indazole in the market. However, this material is related to chemical synthesis, and many professional fields and related regulations are involved.
    The fluctuation of market prices often depends on changes in supply and demand, quality and craftsmanship. Its unusual goods are easy, and in the chemical reagent market, the price may be tens to hundreds of gold per gram, depending on the source and purity. If you buy from a professional reagent, the price of pure excellent is high; if you buy from a large-scale and well-connected business, you may get the best price.
    It must be clear that such chemicals are subject to strict regulation, and purchasers must have appropriate qualifications and follow relevant procedures to ensure safety and compliance. Trading without permission involves the risk of violations. Therefore, when asking for a price, it should be in accordance with the law and regulations, and do not flout the rules because of the price. To confirm the price, you can consult the chemical reagent supplier and state your needs in detail before obtaining the actual price.