2 Chloromethyl 3h Benzo D Imidazole 5 Carbonitrile
quinoline thiophene imidazole thiazole

2-(chloromethyl)-3H-benzo[d]imidazole-5-carbonitrile

    Specifications

    HS Code

    895020

    Chemical Formula C9H6ClN3
    Molecular Weight 189.62
    Appearance Solid (predicted)
    Solubility In Water Low (predicted)
    Logp 1.99 (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading 2-(chloromethyl)-3H-benzo[d]imidazole-5-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2- (chloromethyl) -3H-benzo [d] imidazole-5-carbonitrile
    2-%28chloromethyl%29-3H-benzo%5Bd%5Dimidazole-5-carbonitrile, this is an organic compound with interesting chemical properties.
    From the structural point of view, it contains key groups such as chloromethyl, benzimidazole ring and nitrile group. Chloromethyl has high reactivity, and can participate in nucleophilic substitution reactions due to the presence of chlorine atoms. Nucleophiles easily attack the carbon atoms connected to the chlorine atoms, causing the chlorine atoms to leave and form new compounds. This reaction has a wide range of uses in organic synthesis, and can introduce different groups to expand the structure and function of the compound.
    Benzimidazole ring endows the compound with unique electronic properties and stability. The ring system has a conjugated structure and a uniform electron cloud distribution, which makes its chemical properties relatively stable. However, the nitrogen atom on the benzimidazole ring has a lone pair of electrons, which can be used as an electron donor to participate in coordination reactions and form complexes with metal ions, which has potential applications in the fields of materials science and biomedicine.
    Nitrile group (-CN) is also an active group. It can be hydrolyzed to form carboxyl groups (-COOH) or reduced to form amine groups (-NH2O). The hydrolysis reaction can occur under acidic or basic conditions, which is an important method for the preparation of carboxyl-containing compounds. The reaction of reducing nitrile groups to amine groups can introduce basic groups into the compounds, changing their acidity and alkalinity and biological activity. < Br >
    2-%28chloromethyl%29-3H-benzo%5Bd%5Dimidazole-5-carbonitrile Due to the characteristics of the groups contained, it exhibits diverse chemical properties and has potential application value in many fields such as organic synthesis, drug research and development, material preparation, etc., providing rich materials for chemical research and related industrial development.
    What are the main uses of 2- (chloromethyl) -3H-benzo [d] imidazole-5-carbonitrile
    2-%28chloromethyl%29-3H-benzo%5Bd%5Dimidazole-5-carbonitrile, this is an organic compound, which can be called 2- (chloromethyl) -3H-benzo [d] imidazole-5-formonitrile in Chinese. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. Gein benzimidazole compounds have various biological activities, such as antibacterial, antiviral, antitumor, etc. In this compound, the presence of chloromethyl and formonitrile groups endows it with specific reactivity and biological activity. By chemically modifying it, a series of derivatives with potential medicinal value can be synthesized.
    In the field of materials science, it may also have important applications. Due to its special structure, polymer materials can be introduced through specific reactions to improve the properties of the material, such as improving the stability and mechanical properties of the material, or endowing the material with special functionality. For example, it can be integrated into the polymer backbone by polymerization reaction, or functional materials with special optical and electrical properties can be prepared, which can emit light and conduct electricity in the field of optoelectronics.
    Furthermore, in organic synthetic chemistry, it is an important starting material for the construction of more complex organic molecules. With its active functional groups, it can participate in many classic organic reactions, such as nucleophilic substitution reactions, cyclization reactions, etc., thereby expanding the structural diversity of organic molecules, laying the foundation for the synthesis of new organic compounds, and promoting the development of organic synthetic chemistry.
    What is the synthesis method of 2- (chloromethyl) -3H-benzo [d] imidazole-5-carbonitrile
    To prepare 2 - (chloromethyl) - 3H - benzo [d] imidazole - 5 - formonitrile, the method is as follows:
    First take the benzimidazole compound as the starting material. In the structure of this material, the benzene ring and the imidazole ring fuse together, which is the basic structure of the reaction.
    One method can introduce a cyanyl group at a suitable position before the benzimidazole. Common cyanide-containing reagents, such as potassium cyanide or sodium cyanide, under appropriate reaction conditions, such as in an organic solvent, add a suitable catalyst, heat and reflux, so that the cyanyl group replaces the hydrogen atom at a specific position on the benzimidazole ring to obtain a cyanide-containing benzimidazole intermediate.
    Then introduce chloromethyl to this intermediate. Chloromethylation reagents can be selected, such as chloromethyl methyl ether or a combination of triformaldehyde and hydrogen chloride. In a suitable reaction environment, such as in the presence of Lewis acid catalysts, such as anhydrous zinc chloride or aluminum trichloride, control the reaction temperature and time, so that the chloromethyl group is successfully connected to the target position of the benzimidazole ring, and the final result is 2- (chloromethyl) -3H-benzo [d] imidazole-5-formonitrile.
    Another method can be used to chloromethylate the initial benzimidazole compound first, and then introduce a cyanide group. This change in order also requires adjusting the reaction conditions, such as reaction solvent, temperature, catalyst, etc., to ensure the smooth progress of each step of the reaction, improve the yield and purity of the product, and finally obtain the required 2- (chloromethyl) -3H-benzo [d] imidazole-5-formonitrile.
    2- (chloromethyl) -3H-benzo [d] imidazole-5-carbonitrile What are the precautions during storage
    2-%28chloromethyl%29-3H-benzo%5Bd%5Dimidazole-5-carbonitrile, this is an organic compound, and many aspects need to be paid attention to during storage.
    First, temperature is very important. It should be stored in a cool place, because high temperature is prone to chemical reactions and changes in its properties. If the temperature is too high, it may cause changes in molecular structure, or accelerate the decomposition rate, which will damage its quality and purity.
    Second, humidity should not be underestimated. It should be placed in a dry place to avoid moisture. Moisture or interact with the compound, causing reactions such as hydrolysis, which affects its chemical stability.
    Third, light also affects. It needs to be stored in a dark place, and some organic compounds are easily irritated by light, causing them to deteriorate. This compound may undergo photochemical reactions due to light, changing its structure and properties.
    Fourth, the choice of storage container is also critical. Containers of suitable materials, such as glass or specific plastic materials, need to be used to ensure that they do not react with the compound, and are well sealed to prevent it from contacting with the air and from being oxidized or reacting with components in the air.
    Fifth, the storage environment needs to be protected from fire sources and oxidants. This compound may be flammable or react violently with oxidants, causing danger.
    Sixth, clear labeling is also important. The name, properties, storage conditions, etc. of the compound should be clearly marked on the container to facilitate access and management, and to prevent safety accidents caused by misoperation.
    In short, when storing 2-%28chloromethyl%29-3H-benzo%5Bd%5Dimidazole-5-carbonitrile, temperature, humidity, light, container, environment and labeling need to be properly handled to ensure its stability and safety.
    2- (chloromethyl) -3H-benzo [d] What is the impact of imidazole-5-carbonitrile on the environment?
    There is currently a substance 2 - (chloromethyl) -3H - benzo [d] imidazole - 5 - formonitrile, and its impact on the environment is worthy of investigation. This substance contains chloromethyl, and the chlorine atom has certain reactivity, or causes a series of chemical changes in the environment.
    If it enters natural water, or due to hydrolysis and other reactions, chlorine ions are released, which changes the chemical composition of the water body and affects the chemical environment in which aquatic organisms live. And the hydrolysis products may have different chemical activities, which interfere with the physiological functions of aquatic organisms, such as respiration and metabolism.
    In the soil environment, it may interact with soil particles, affecting the physical and chemical properties of the soil. Due to its structure containing aromatic rings and nitrile groups, or difficult to be rapidly degraded by soil microorganisms, it accumulates in the soil, disrupts the soil ecological balance, affects the absorption of nutrients by plant roots, or directly poisons plants, causing plant growth and development to be hindered.
    In the atmospheric environment, although its volatilization amount at room temperature may be limited, under specific conditions, such as high temperature, strong light irradiation, or volatilization into the atmosphere, through photochemical reactions, secondary pollutants are generated, which affect air quality and cause harm to human and biological respiratory systems.
    Furthermore, if this substance is transmitted through the food chain, due to bioenrichment, the concentration in high nutrient level organisms gradually increases, or it has a profound and complex impact on biodiversity and ecosystem stability.