2 Butyl 1h Imidazole 5 Carbaldehyde
quinoline thiophene imidazole thiazole

2-butyl-1H-imidazole-5-carbaldehyde

    Specifications

    HS Code

    465820

    Chemical Formula C8H10N2O
    Molecular Weight 150.18
    Appearance Solid (predicted)
    Boiling Point Predicted around 323.8°C at 760 mmHg
    Density Predicted around 1.14 g/cm³
    Flash Point Predicted around 149.6°C
    Solubility In Water Low solubility (due to non - polar alkyl group)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Pka The imidazole ring nitrogen can have a pKa around 7 - 8 for protonation

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    Frequently Asked Questions

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    What are the main uses of 2-butyl-1H-imidazole-5-carbaldehyde?
    2-butyl-1H-imidazole-5-carbalaldehyde, or 2-butyl-1H-imidazole-5-formaldehyde, is widely used. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of many drugs. Because of its unique chemical structure, it can react with other compounds to build complex and biologically active molecular structures, like some new therapeutic drugs for specific diseases, in the development and synthesis path, 2-butyl-1H-imidazole-5-formaldehyde is an indispensable starting material or an important reaction participant.
    In the field of materials science, it can participate in the preparation of special functional materials. By means of polymerization with other functional monomers, the material is endowed with good optical properties, thermal stability or special adsorption properties. For example, in the preparation of porous materials with high sensitivity to specific gases, 2-butyl-1H-imidazole-5-formaldehyde can be used as a structure-directing agent or reactive monomer, which affects the pore structure and surface properties of the material, thereby enhancing the application potential of the material in gas separation, environmental monitoring, etc.
    In addition, in organic synthetic chemistry, it is also an important building block for the construction of diverse imidazole derivatives. Through various chemical modifications to its aldehyde and butyl groups, a series of imidazole compounds with different substituents can be synthesized. These derivatives have shown unique properties and application value in the fields of catalysis and dyes, such as as as high-efficiency catalysts for certain organic reactions, or the preparation of new dyes with special color and photostability.
    What are 2-butyl-1H-imidazole-5-carbaldehyde synthesis methods?
    Fu 2 - butyl - 1H - imidazole - 5 - carbalaldehyde, there are various synthesis methods. First, it can be obtained from a suitable starting material through a multi-step reaction. First, take a compound containing a specific functional group and, under suitable reaction conditions, such as catalysis with a catalyst, make it undergo a functional group conversion reaction at a specific temperature, pressure and solvent environment.
    The starting material or the structural unit that can be converted into an imidazole ring is cyclized to construct the structure of the imidazole ring. This cyclization reaction requires precise regulation of reaction parameters, such as temperature or between tens of degrees Celsius and hundreds of degrees Celsius, depending on the reagent used and the reaction mechanism. The choice of catalyst is also crucial, either a metal catalyst or an organic base catalyst, which can promote the reaction process and improve the reaction efficiency.
    Then, modify the resulting imidazole compound. The introduction of butyl into the molecule can be achieved by nucleophilic substitution. Select a suitable halobutane and react with the imidazole compound in the presence of a base. The type and amount of base depend on the rate and selectivity of the reaction.
    As for the introduction of aldehyde groups, it can be obtained by oxidation reaction or specific substitution reaction. If the oxidation reaction is carried out, a suitable oxidizing agent should be selected, such as a mild oxidizing agent, which can oxidize specific functional groups to aldehyde groups without affecting the structure of other parts of the molecule. < Br >
    Or there may be other synthesis routes, such as using different starting materials and following different reaction mechanisms. However, no matter what method, the reaction conditions need to be carefully controlled, and the stability and reaction selectivity of the intermediate need to be paid attention to in order to achieve the purpose of high-efficiency synthesis of 2-butyl-1H-imidazole-5-carbalaldehyde. During the synthesis process, the products of each step of the reaction need to be separated and purified, and the purity of the products can be ensured by means such as column chromatography and recrystallization, which lays a good foundation for the next reaction.
    What are the physical properties of 2-butyl-1H-imidazole-5-carbaldehyde?
    2 - butyl - 1H - imidazole - 5 - carbalaldehyde is an organic compound with unique physical properties. It is usually a solid or viscous liquid at room temperature, which is determined by intermolecular forces and structural characteristics. The substance has a specific melting point and boiling point. The melting point may be higher due to the close arrangement and interaction of molecules, and moderate thermal energy is required to cause the disintegration of the lattice structure. The boiling point varies according to the strength of the intermolecular force and molecular weight, or boils at a specific temperature range, causing the transition from liquid to gaseous state.
    In terms of solubility, it exhibits different dissolution behaviors in polar and non-polar solvents due to the presence of polar aldehyde groups and relatively non-polar butyl groups. In polar organic solvents such as ethanol and acetone, aldehyde groups can form hydrogen bonds or other polar interactions with solvent molecules, resulting in a certain solubility; in non-polar solvents such as hexane, butyl is non-polar or has a certain solubility, but it is generally inferior to polar solvents.
    In addition, 2-butyl-1H-imidazole-5-carbalaldehyde has a certain degree of volatility, but the volatility may be limited by strong intermolecular forces. Its odor may have a special irritating or aromatic odor due to the presence of aldehyde groups. Density is also one of its physical properties, or it is different from water according to the degree of molecular packing compactness and molecular weight, or greater or less than the density of water. These physical properties are crucial in the separation, purification and application of the compound.
    What are the chemical properties of 2-butyl-1H-imidazole-5-carbaldehyde?
    2 - butyl - 1H - imidazole - 5 - carbalaldehyde (2 - butyl - 1H - imidazole - 5 - formaldehyde) is one of the organic compounds. Its chemical properties are rich and unique, let me tell you one by one.
    This compound has an aldehyde group, which is a functional group with active chemical properties. It can undergo oxidation reaction. When it encounters mild oxidants, such as tolan reagent (silver ammonia solution), it can be oxidized to carboxylic acid to form 2-butyl-1H-imidazole-5-carboxylic acid (2-butyl-1H-imidazole-5-carboxylic acid). This reaction can be used for qualitative testing of aldehyde groups. Due to the formation of silver mirrors in the reaction, the phenomenon is significant. In case of strong oxidants, such as potassium permanganate, it can also be oxidized, but the product is more complex.
    Meanwhile, aldehyde groups can participate in the reduction reaction. Under the action of suitable reducing agents, such as sodium borohydride, aldehyde groups can be reduced to hydroxyl groups to obtain 2-butyl-1H-imidazole-5-methanol (2-butyl-1H-imidazole-5-methanol).
    Furthermore, the compound contains an imidazole ring, which has certain aromatic and basic properties. The lone pair electrons on the nitrogen atom of the imidazole ring can bind to the proton and exhibit alkalinity. This alkalinity enables it to react with acids to form corresponding salts. And the electron cloud distribution characteristics of the imidazole ring make it possible to participate in the electrophilic substitution reaction. Under appropriate conditions, substituents such as halogen atoms and nitro groups can be introduced into the imidazole ring.
    And because there are butyl groups in the molecule, and butyl is alkyl, it has a certain electron-giving effect, which affects the overall electron cloud distribution of the molecule, which in turn affects the reactivity of aldehyde groups and imidazole rings. Its presence also increases the lipid solubility of the molecule and affects the solubility of the compound in different solvents.
    In summary, 2-butyl-1H-imidazole-5-carbalaldehyde exhibits diverse chemical properties due to its functional groups and structural characteristics, and has potential application value in organic synthesis and other fields.
    What is the price of 2-butyl-1H-imidazole-5-carbaldehyde in the market?
    I look at the prices in the market, which are changing rapidly, and it is difficult to determine the price of 2-butyl-1H-imidazole-5-carbalaldehyde. This is a fine chemical, and its price is often affected by many factors.
    First, the situation of supply and demand has a great influence. If there are many people who want it, but the supply is small, the price will rise; conversely, if the supply exceeds the demand, the price may decline. Second, the price of raw materials is also the key. Its synthesis requires specific raw materials. If the price of raw materials is high, the cost will increase, and the price of finished products will also increase. Furthermore, the difficulty of production and the complexity of technology are all related to cost and price. < Br >
    In addition, market competition, regional differences, transportation costs, etc., all have an impact on its price. Therefore, to know the exact price of this product, you should carefully check the chemical product trading platform, consult the chemical raw material supplier, or refer to the recent market conditions report to obtain relatively accurate price information.